Fragment List : JM9Y9
Number of Fragments : 858 Ligand Residue Name : SAM Ligand Fragment Number : 416
1(A:6798:ALA )
2(A:6799:SER )
3(A:6800:SER )
4(A:6801:GLN )
5(A:6802:ALA )
6(A:6803:TRP )
7(A:6804:GLN )
8(A:6805:PRO )
9(A:6806:GLY )
10(A:6807:VAL )
11(A:6808:ALA )
12(A:6809:MET )
13(A:6810:PRO )
14(A:6811:ASN )
15(A:6812:LEU )
16(A:6813:TYR )
17(A:6814:LYS )
18(A:6815:MET )
19(A:6816:GLN )
20(A:6817:ARG )
21(A:6818:MET )
22(A:6819:LEU )
23(A:6820:LEU )
24(A:6821:GLU )
25(A:6822:LYS )
26(A:6823:CYS )
27(A:6824:ASP )
28(A:6825:LEU )
29(A:6826:GLN )
30(A:6827:ASN )
31(A:6828:TYR )
32(A:6829:GLY )
33(A:6830:ASP )
34(A:6831:SER )
35(A:6832:ALA )
36(A:6833:THR )
37(A:6834:LEU )
38(A:6835:PRO )
39(A:6836:LYS )
40(A:6837:GLY )
41(A:6838:ILE )
42(A:6839:MET )
43(A:6840:MET )
44(A:6841:ASN )
45(A:6842:VAL )
46(A:6843:ALA )
47(A:6844:LYS )
48(A:6845:TYR )
49(A:6846:THR )
50(A:6847:GLN )
51(A:6848:LEU )
52(A:6849:CYS )
53(A:6850:GLN )
54(A:6851:TYR )
55(A:6852:LEU )
56(A:6853:ASN )
57(A:6854:THR )
58(A:6855:LEU )
59(A:6856:THR )
60(A:6857:LEU )
61(A:6858:ALA )
62(A:6859:VAL )
63(A:6860:PRO )
64(A:6861:TYR )
65(A:6862:ASN )
66(A:6863:MET )
67(A:6864:ARG )
68(A:6865:VAL )
69(A:6866:ILE )
70(A:6867:HIS )
71(A:6868:PHE )
72(A:6869:GLY )
73(A:6870:ALA )
74(A:6871:GLY )
75(A:6872:SER )
76(A:6873:ASP )
77(A:6874:LYS )
78(A:6875:GLY )
79(A:6876:VAL )
80(A:6877:ALA )
81(A:6878:PRO )
82(A:6879:GLY )
83(A:6880:THR )
84(A:6881:ALA )
85(A:6882:VAL )
86(A:6883:LEU )
87(A:6884:ARG )
88(A:6885:GLN )
89(A:6886:TRP )
90(A:6887:LEU )
91(A:6888:PRO )
92(A:6889:THR )
93(A:6890:GLY )
94(A:6891:THR )
95(A:6892:LEU )
96(A:6893:LEU )
97(A:6894:VAL )
98(A:6895:ASP )
99(A:6896:SER )
100(A:6897:ASP )
101(A:6898:LEU )
102(A:6899:ASN )
103(A:6900:ASP )
104(A:6901:PHE )
105(A:6902:VAL )
106(A:6903:SER )
107(A:6904:ASP )
108(A:6905:ALA )
109(A:6906:ASP )
110(A:6907:SER )
111(A:6908:THR )
112(A:6909:LEU )
113(A:6910:ILE )
114(A:6911:GLY )
115(A:6912:ASP )
116(A:6913:CYS )
117(A:6914:ALA )
118(A:6915:THR )
119(A:6916:VAL )
120(A:6917:HIS )
121(A:6918:THR )
122(A:6919:ALA )
123(A:6920:ASN )
124(A:6921:LYS )
125(A:6922:TRP )
126(A:6923:ASP )
127(A:6924:LEU )
128(A:6925:ILE )
129(A:6926:ILE )
130(A:6927:SER )
131(A:6928:ASP )
132(A:6929:MET )
133(A:6930:TYR )
134(A:6931:ASP )
135(A:6932:PRO )
136(A:6933:LYS )
137(A:6934:THR )
138(A:6935:LYS )
139(A:6936:ASN )
140(A:6937:VAL )
141(A:6938:THR )
142(A:6939:LYS )
143(A:6940:GLU )
144(A:6941:ASN )
145(A:6942:ASP )
146(A:6943:SER )
147(A:6944:LYS )
148(A:6945:GLU )
149(A:6946:GLY )
150(A:6947:PHE )
151(A:6948:PHE )
152(A:6949:THR )
153(A:6950:TYR )
154(A:6951:ILE )
155(A:6952:CYS )
156(A:6953:GLY )
157(A:6954:PHE )
158(A:6955:ILE )
159(A:6956:GLN )
160(A:6957:GLN )
161(A:6958:LYS )
162(A:6959:LEU )
163(A:6960:ALA )
164(A:6961:LEU )
165(A:6962:GLY )
166(A:6963:GLY )
167(A:6964:SER )
168(A:6965:VAL )
169(A:6966:ALA )
170(A:6967:ILE )
171(A:6968:LYS )
172(A:6969:ILE )
173(A:6970:THR )
174(A:6971:GLU )
175(A:6972:HIS )
176(A:6973:SER )
177(A:6974:TRP )
178(A:6975:ASN )
179(A:6976:ALA )
180(A:6977:ASP )
181(A:6978:LEU )
182(A:6979:TYR )
183(A:6980:LYS )
184(A:6981:LEU )
185(A:6982:MET )
186(A:6983:GLY )
187(A:6984:HIS )
188(A:6985:PHE )
189(A:6986:ALA )
190(A:6987:TRP )
191(A:6988:TRP )
192(A:6989:THR )
193(A:6990:ALA )
194(A:6991:PHE )
195(A:6992:VAL )
196(A:6993:THR )
197(A:6994:ASN )
198(A:6995:VAL )
199(A:6996:ASN )
200(A:6997:ALA )
201(A:6998:SER )
202(A:6999:SER )
203(A:7000:SER )
204(A:7001:GLU )
205(A:7002:ALA )
206(A:7003:PHE )
207(A:7004:LEU )
208(A:7005:ILE )
209(A:7006:GLY )
210(A:7007:CYS )
211(A:7008:ASN )
212(A:7009:TYR )
213(A:7010:LEU )
214(A:7011:GLY )
215(A:7012:LYS )
216(A:7013:PRO )
217(A:7014:ARG )
218(A:7015:GLU )
219(A:7016:GLN )
220(A:7017:ILE )
221(A:7018:ASP )
222(A:7019:GLY )
223(A:7020:TYR )
224(A:7021:VAL )
225(A:7022:MET )
226(A:7023:HIS )
227(A:7024:ALA )
228(A:7025:ASN )
229(A:7026:TYR )
230(A:7027:ILE )
231(A:7028:PHE )
232(A:7029:TRP )
233(A:7030:ARG )
234(A:7031:ASN )
235(A:7032:THR )
236(A:7033:ASN )
237(A:7034:PRO )
238(A:7035:ILE )
239(A:7036:GLN )
240(A:7037:LEU )
241(A:7038:SER )
242(A:7039:SER )
243(A:7040:TYR )
244(A:7041:SER )
245(A:7042:LEU )
246(A:7043:PHE )
247(A:7044:ASP )
248(A:7045:MET )
249(A:7046:SER )
250(A:7047:LYS )
251(A:7048:PHE )
252(A:7049:PRO )
253(A:7050:LEU )
254(A:7051:LYS )
255(A:7052:LEU )
256(A:7053:ARG )
257(A:7054:GLY )
258(A:7055:THR )
259(A:7056:ALA )
260(A:7057:VAL )
261(A:7058:MET )
262(A:7059:SER )
263(A:7060:LEU )
264(A:7061:LYS )
265(A:7062:GLU )
266(A:7063:GLY )
267(A:7064:GLN )
268(A:7065:ILE )
269(A:7066:ASN )
270(A:7067:ASP )
271(A:7068:MET )
272(A:7069:ILE )
273(A:7070:LEU )
274(A:7071:SER )
275(A:7072:LEU )
276(A:7073:LEU )
277(A:7074:SER )
278(A:7075:LYS )
279(A:7076:GLY )
280(A:7077:ARG )
281(A:7078:LEU )
282(A:7079:ILE )
283(A:7080:ILE )
284(A:7081:ARG )
285(A:7082:GLU )
286(A:7083:ASN )
287(A:7084:ASN )
288(A:7085:ARG )
289(A:7086:VAL )
290(A:7087:VAL )
291(A:7088:ILE )
292(A:7089:SER )
293(A:7090:SER )
294(A:7091:ASP )
295(A:7092:VAL )
296(A:7093:LEU )
297(A:7094:VAL )
298(A:7095:ASN )
299(A:7096:ASN )
300(B:4271:ALA )
301(B:4272:PHE )
302(B:4273:ALA )
303(B:4274:VAL )
304(B:4275:ASP )
305(B:4276:ALA )
306(B:4277:ALA )
307(B:4278:LYS )
308(B:4279:ALA )
309(B:4280:TYR )
310(B:4281:LYS )
311(B:4282:ASP )
312(B:4283:TYR )
313(B:4284:LEU )
314(B:4285:ALA )
315(B:4286:SER )
316(B:4287:GLY )
317(B:4288:GLY )
318(B:4289:GLN )
319(B:4290:PRO )
320(B:4291:ILE )
321(B:4292:THR )
322(B:4293:ASN )
323(B:4294:CYS )
324(B:4295:VAL )
325(B:4296:LYS )
326(B:4297:MET )
327(B:4298:LEU )
328(B:4299:CYS )
329(B:4300:THR )
330(B:4301:HIS )
331(B:4302:THR )
332(B:4303:GLY )
333(B:4304:THR )
334(B:4305:GLY )
335(B:4306:GLN )
336(B:4307:ALA )
337(B:4308:ILE )
338(B:4309:THR )
339(B:4310:VAL )
340(B:4311:THR )
341(B:4312:PRO )
342(B:4313:GLU )
343(B:4314:ALA )
344(B:4315:ASN )
345(B:4316:MET )
346(B:4317:ASP )
347(B:4318:GLN )
348(B:4319:GLU )
349(B:4320:SER )
350(B:4321:PHE )
351(B:4322:GLY )
352(B:4323:GLY )
353(B:4324:ALA )
354(B:4325:SER )
355(B:4326:CYS )
356(B:4327:CYS )
357(B:4328:LEU )
358(B:4329:TYR )
359(B:4330:CYS )
360(B:4331:ARG )
361(B:4332:CYS )
362(B:4333:HIS )
363(B:4334:ILE )
364(B:4335:ASP )
365(B:4336:HIS )
366(B:4337:PRO )
367(B:4338:ASN )
368(B:4339:PRO )
369(B:4340:LYS )
370(B:4341:GLY )
371(B:4342:PHE )
372(B:4343:CYS )
373(B:4344:ASP )
374(B:4345:LEU )
375(B:4346:LYS )
376(B:4347:GLY )
377(B:4348:LYS )
378(B:4349:TYR )
379(B:4350:VAL )
380(B:4351:GLN )
381(B:4352:ILE )
382(B:4353:PRO )
383(B:4354:THR )
384(B:4355:THR )
385(B:4356:CYS )
386(B:4357:ALA )
387(B:4358:ASN )
388(B:4359:ASP )
389(B:4360:PRO )
390(B:4361:VAL )
391(B:4362:GLY )
392(B:4363:PHE )
393(B:4364:THR )
394(B:4365:LEU )
395(B:4366:LYS )
396(B:4367:ASN )
397(B:4368:THR )
398(B:4369:VAL )
399(B:4370:CYS )
400(B:4371:THR )
401(B:4372:VAL )
402(B:4373:CYS )
403(B:4374:GLY )
404(B:4375:MET )
405(B:4376:TRP )
406(B:4377:LYS )
407(B:4378:GLY )
408(B:4379:TYR )
409(B:4380:GLY )
410(B:4381:CYS )
411(B:4382:SER )
412(B:4383:CYS )
413(B:4384:ASP )
414(B:4385:GLN )
415(B:4386:LEU )
416(A:7102:SAM )Lignad
417(A:7201:HOH )
418(A:7202:HOH )
419(A:7203:HOH )
420(A:7204:HOH )
421(A:7205:HOH )
422(A:7206:HOH )
423(A:7207:HOH )
424(A:7208:HOH )
425(A:7209:HOH )
426(A:7210:HOH )
427(A:7211:HOH )
428(A:7212:HOH )
429(A:7213:HOH )
430(A:7214:HOH )
431(A:7215:HOH )
432(A:7216:HOH )
433(A:7217:HOH )
434(A:7218:HOH )
435(A:7219:HOH )
436(A:7220:HOH )
437(A:7221:HOH )
438(A:7222:HOH )
439(A:7223:HOH )
440(A:7224:HOH )
441(A:7225:HOH )
442(A:7226:HOH )
443(A:7227:HOH )
444(A:7228:HOH )
445(A:7229:HOH )
446(A:7230:HOH )
447(A:7231:HOH )
448(A:7232:HOH )
449(A:7233:HOH )
450(A:7234:HOH )
451(A:7235:HOH )
452(A:7236:HOH )
453(A:7237:HOH )
454(A:7238:HOH )
455(A:7239:HOH )
456(A:7240:HOH )
457(A:7241:HOH )
458(A:7242:HOH )
459(A:7243:HOH )
460(A:7244:HOH )
461(A:7245:HOH )
462(A:7246:HOH )
463(A:7247:HOH )
464(A:7248:HOH )
465(A:7249:HOH )
466(A:7250:HOH )
467(A:7251:HOH )
468(A:7252:HOH )
469(A:7253:HOH )
470(A:7254:HOH )
471(A:7255:HOH )
472(A:7256:HOH )
473(A:7257:HOH )
474(A:7258:HOH )
475(A:7259:HOH )
476(A:7260:HOH )
477(A:7261:HOH )
478(A:7262:HOH )
479(A:7263:HOH )
480(A:7264:HOH )
481(A:7265:HOH )
482(A:7266:HOH )
483(A:7267:HOH )
484(A:7268:HOH )
485(A:7269:HOH )
486(A:7270:HOH )
487(A:7271:HOH )
488(A:7272:HOH )
489(A:7273:HOH )
490(A:7274:HOH )
491(A:7275:HOH )
492(A:7276:HOH )
493(A:7277:HOH )
494(A:7278:HOH )
495(A:7279:HOH )
496(A:7280:HOH )
497(A:7281:HOH )
498(A:7282:HOH )
499(A:7283:HOH )
500(A:7284:HOH )
501(A:7285:HOH )
502(A:7286:HOH )
503(A:7287:HOH )
504(A:7288:HOH )
505(A:7289:HOH )
506(A:7290:HOH )
507(A:7291:HOH )
508(A:7292:HOH )
509(A:7293:HOH )
510(A:7294:HOH )
511(A:7295:HOH )
512(A:7296:HOH )
513(A:7297:HOH )
514(A:7298:HOH )
515(A:7299:HOH )
516(A:7300:HOH )
517(A:7301:HOH )
518(A:7302:HOH )
519(A:7303:HOH )
520(A:7304:HOH )
521(A:7305:HOH )
522(A:7306:HOH )
523(A:7307:HOH )
524(A:7308:HOH )
525(A:7309:HOH )
526(A:7310:HOH )
527(A:7311:HOH )
528(A:7312:HOH )
529(A:7313:HOH )
530(A:7314:HOH )
531(A:7315:HOH )
532(A:7316:HOH )
533(A:7317:HOH )
534(A:7318:HOH )
535(A:7319:HOH )
536(A:7320:HOH )
537(A:7321:HOH )
538(A:7322:HOH )
539(A:7323:HOH )
540(A:7324:HOH )
541(A:7325:HOH )
542(A:7326:HOH )
543(A:7327:HOH )
544(A:7328:HOH )
545(A:7329:HOH )
546(A:7330:HOH )
547(A:7331:HOH )
548(A:7332:HOH )
549(A:7333:HOH )
550(A:7334:HOH )
551(A:7335:HOH )
552(A:7336:HOH )
553(A:7337:HOH )
554(A:7338:HOH )
555(A:7339:HOH )
556(A:7340:HOH )
557(A:7341:HOH )
558(A:7342:HOH )
559(A:7343:HOH )
560(A:7344:HOH )
561(A:7345:HOH )
562(A:7346:HOH )
563(A:7347:HOH )
564(A:7348:HOH )
565(A:7349:HOH )
566(A:7350:HOH )
567(A:7351:HOH )
568(A:7352:HOH )
569(A:7353:HOH )
570(A:7354:HOH )
571(A:7355:HOH )
572(A:7356:HOH )
573(A:7357:HOH )
574(A:7358:HOH )
575(A:7359:HOH )
576(A:7360:HOH )
577(A:7361:HOH )
578(A:7362:HOH )
579(A:7363:HOH )
580(A:7364:HOH )
581(A:7365:HOH )
582(A:7366:HOH )
583(A:7367:HOH )
584(A:7368:HOH )
585(A:7369:HOH )
586(A:7370:HOH )
587(A:7371:HOH )
588(A:7372:HOH )
589(A:7373:HOH )
590(A:7374:HOH )
591(A:7375:HOH )
592(A:7376:HOH )
593(A:7377:HOH )
594(A:7378:HOH )
595(A:7379:HOH )
596(A:7380:HOH )
597(A:7381:HOH )
598(A:7382:HOH )
599(A:7383:HOH )
600(A:7384:HOH )
601(A:7385:HOH )
602(A:7386:HOH )
603(A:7387:HOH )
604(A:7388:HOH )
605(A:7389:HOH )
606(A:7390:HOH )
607(A:7391:HOH )
608(A:7392:HOH )
609(A:7393:HOH )
610(A:7394:HOH )
611(A:7395:HOH )
612(A:7396:HOH )
613(A:7397:HOH )
614(A:7398:HOH )
615(A:7399:HOH )
616(A:7400:HOH )
617(A:7401:HOH )
618(A:7402:HOH )
619(A:7403:HOH )
620(A:7404:HOH )
621(A:7405:HOH )
622(A:7406:HOH )
623(A:7407:HOH )
624(A:7408:HOH )
625(A:7409:HOH )
626(A:7410:HOH )
627(A:7411:HOH )
628(A:7412:HOH )
629(A:7413:HOH )
630(A:7414:HOH )
631(A:7415:HOH )
632(A:7416:HOH )
633(A:7417:HOH )
634(A:7418:HOH )
635(A:7419:HOH )
636(A:7420:HOH )
637(A:7421:HOH )
638(A:7422:HOH )
639(A:7423:HOH )
640(A:7424:HOH )
641(A:7425:HOH )
642(A:7426:HOH )
643(A:7427:HOH )
644(A:7428:HOH )
645(A:7429:HOH )
646(A:7430:HOH )
647(A:7431:HOH )
648(A:7432:HOH )
649(A:7433:HOH )
650(A:7434:HOH )
651(A:7435:HOH )
652(A:7436:HOH )
653(A:7437:HOH )
654(A:7438:HOH )
655(A:7439:HOH )
656(A:7440:HOH )
657(A:7441:HOH )
658(A:7442:HOH )
659(A:7443:HOH )
660(A:7444:HOH )
661(A:7445:HOH )
662(A:7446:HOH )
663(A:7447:HOH )
664(A:7448:HOH )
665(A:7449:HOH )
666(A:7450:HOH )
667(A:7451:HOH )
668(A:7452:HOH )
669(A:7453:HOH )
670(A:7454:HOH )
671(A:7455:HOH )
672(A:7456:HOH )
673(A:7457:HOH )
674(A:7458:HOH )
675(A:7459:HOH )
676(A:7460:HOH )
677(A:7461:HOH )
678(A:7462:HOH )
679(A:7463:HOH )
680(A:7464:HOH )
681(A:7465:HOH )
682(A:7466:HOH )
683(A:7467:HOH )
684(A:7468:HOH )
685(A:7469:HOH )
686(A:7470:HOH )
687(A:7471:HOH )
688(A:7472:HOH )
689(A:7473:HOH )
690(A:7474:HOH )
691(A:7475:HOH )
692(A:7476:HOH )
693(A:7477:HOH )
694(A:7478:HOH )
695(A:7479:HOH )
696(A:7480:HOH )
697(A:7481:HOH )
698(A:7482:HOH )
699(A:7483:HOH )
700(A:7484:HOH )
701(A:7485:HOH )
702(A:7486:HOH )
703(A:7487:HOH )
704(A:7488:HOH )
705(A:7489:HOH )
706(A:7490:HOH )
707(A:7491:HOH )
708(A:7492:HOH )
709(A:7493:HOH )
710(A:7494:HOH )
711(A:7495:HOH )
712(A:7496:HOH )
713(A:7497:HOH )
714(A:7498:HOH )
715(A:7499:HOH )
716(A:7500:HOH )
717(A:7501:HOH )
718(A:7502:HOH )
719(A:7503:HOH )
720(A:7504:HOH )
721(A:7505:HOH )
722(A:7506:HOH )
723(A:7507:HOH )
724(A:7508:HOH )
725(A:7509:HOH )
726(A:7510:HOH )
727(A:7511:HOH )
728(A:7512:HOH )
729(A:7513:HOH )
730(A:7514:HOH )
731(A:7515:HOH )
732(A:7516:HOH )
733(A:7517:HOH )
734(A:7518:HOH )
735(A:7519:HOH )
736(A:7520:HOH )
737(A:7521:HOH )
738(A:7522:HOH )
739(A:7523:HOH )
740(A:7524:HOH )
741(A:7525:HOH )
742(A:7526:HOH )
743(A:7527:HOH )
744(A:7528:HOH )
745(A:7529:HOH )
746(A:7530:HOH )
747(A:7531:HOH )
748(A:7532:HOH )
749(A:7533:HOH )
750(A:7534:HOH )
751(A:7535:HOH )
752(A:7536:HOH )
753(A:7537:HOH )
754(B:4501:HOH )
755(B:4502:HOH )
756(B:4503:HOH )
757(B:4504:HOH )
758(B:4505:HOH )
759(B:4506:HOH )
760(B:4507:HOH )
761(B:4508:HOH )
762(B:4509:HOH )
763(B:4510:HOH )
764(B:4511:HOH )
765(B:4512:HOH )
766(B:4513:HOH )
767(B:4514:HOH )
768(B:4515:HOH )
769(B:4516:HOH )
770(B:4517:HOH )
771(B:4518:HOH )
772(B:4519:HOH )
773(B:4520:HOH )
774(B:4521:HOH )
775(B:4522:HOH )
776(B:4523:HOH )
777(B:4524:HOH )
778(B:4525:HOH )
779(B:4526:HOH )
780(B:4527:HOH )
781(B:4528:HOH )
782(B:4529:HOH )
783(B:4530:HOH )
784(B:4531:HOH )
785(B:4532:HOH )
786(B:4533:HOH )
787(B:4534:HOH )
788(B:4535:HOH )
789(B:4536:HOH )
790(B:4537:HOH )
791(B:4538:HOH )
792(B:4539:HOH )
793(B:4540:HOH )
794(B:4541:HOH )
795(B:4542:HOH )
796(B:4543:HOH )
797(B:4544:HOH )
798(B:4545:HOH )
799(B:4546:HOH )
800(B:4547:HOH )
801(B:4548:HOH )
802(B:4549:HOH )
803(B:4550:HOH )
804(B:4551:HOH )
805(B:4552:HOH )
806(B:4553:HOH )
807(B:4554:HOH )
808(B:4555:HOH )
809(B:4556:HOH )
810(B:4557:HOH )
811(B:4558:HOH )
812(B:4559:HOH )
813(B:4560:HOH )
814(B:4561:HOH )
815(B:4562:HOH )
816(B:4563:HOH )
817(B:4564:HOH )
818(B:4565:HOH )
819(B:4566:HOH )
820(B:4567:HOH )
821(B:4568:HOH )
822(B:4569:HOH )
823(B:4570:HOH )
824(B:4571:HOH )
825(B:4572:HOH )
826(B:4573:HOH )
827(B:4574:HOH )
828(B:4575:HOH )
829(B:4576:HOH )
830(B:4577:HOH )
831(B:4578:HOH )
832(B:4579:HOH )
833(B:4580:HOH )
834(B:4581:HOH )
835(B:4582:HOH )
836(B:4583:HOH )
837(B:4584:HOH )
838(B:4585:HOH )
839(B:4586:HOH )
840(B:4587:HOH )
841(B:4588:HOH )
842(B:4589:HOH )
843(B:4590:HOH )
844(B:4591:HOH )
845(B:4592:HOH )
846(B:4593:HOH )
847(B:4594:HOH )
848(B:4595:HOH )
849(B:4596:HOH )
850(B:4597:HOH )
851(B:4598:HOH )
852(B:4599:HOH )
853(B:4600:HOH )
854(B:4601:HOH )
855(B:4602:HOH )
856(B:4603:HOH )
857(B:4604:HOH )
858(B:4605:HOH )
2(A:6799:SER )
3(A:6800:SER )
4(A:6801:GLN )
5(A:6802:ALA )
6(A:6803:TRP )
7(A:6804:GLN )
8(A:6805:PRO )
9(A:6806:GLY )
10(A:6807:VAL )
11(A:6808:ALA )
12(A:6809:MET )
13(A:6810:PRO )
14(A:6811:ASN )
15(A:6812:LEU )
16(A:6813:TYR )
17(A:6814:LYS )
18(A:6815:MET )
19(A:6816:GLN )
20(A:6817:ARG )
21(A:6818:MET )
22(A:6819:LEU )
23(A:6820:LEU )
24(A:6821:GLU )
25(A:6822:LYS )
26(A:6823:CYS )
27(A:6824:ASP )
28(A:6825:LEU )
29(A:6826:GLN )
30(A:6827:ASN )
31(A:6828:TYR )
32(A:6829:GLY )
33(A:6830:ASP )
34(A:6831:SER )
35(A:6832:ALA )
36(A:6833:THR )
37(A:6834:LEU )
38(A:6835:PRO )
39(A:6836:LYS )
40(A:6837:GLY )
41(A:6838:ILE )
42(A:6839:MET )
43(A:6840:MET )
44(A:6841:ASN )
45(A:6842:VAL )
46(A:6843:ALA )
47(A:6844:LYS )
48(A:6845:TYR )
49(A:6846:THR )
50(A:6847:GLN )
51(A:6848:LEU )
52(A:6849:CYS )
53(A:6850:GLN )
54(A:6851:TYR )
55(A:6852:LEU )
56(A:6853:ASN )
57(A:6854:THR )
58(A:6855:LEU )
59(A:6856:THR )
60(A:6857:LEU )
61(A:6858:ALA )
62(A:6859:VAL )
63(A:6860:PRO )
64(A:6861:TYR )
65(A:6862:ASN )
66(A:6863:MET )
67(A:6864:ARG )
68(A:6865:VAL )
69(A:6866:ILE )
70(A:6867:HIS )
71(A:6868:PHE )
72(A:6869:GLY )
73(A:6870:ALA )
74(A:6871:GLY )
75(A:6872:SER )
76(A:6873:ASP )
77(A:6874:LYS )
78(A:6875:GLY )
79(A:6876:VAL )
80(A:6877:ALA )
81(A:6878:PRO )
82(A:6879:GLY )
83(A:6880:THR )
84(A:6881:ALA )
85(A:6882:VAL )
86(A:6883:LEU )
87(A:6884:ARG )
88(A:6885:GLN )
89(A:6886:TRP )
90(A:6887:LEU )
91(A:6888:PRO )
92(A:6889:THR )
93(A:6890:GLY )
94(A:6891:THR )
95(A:6892:LEU )
96(A:6893:LEU )
97(A:6894:VAL )
98(A:6895:ASP )
99(A:6896:SER )
100(A:6897:ASP )
101(A:6898:LEU )
102(A:6899:ASN )
103(A:6900:ASP )
104(A:6901:PHE )
105(A:6902:VAL )
106(A:6903:SER )
107(A:6904:ASP )
108(A:6905:ALA )
109(A:6906:ASP )
110(A:6907:SER )
111(A:6908:THR )
112(A:6909:LEU )
113(A:6910:ILE )
114(A:6911:GLY )
115(A:6912:ASP )
116(A:6913:CYS )
117(A:6914:ALA )
118(A:6915:THR )
119(A:6916:VAL )
120(A:6917:HIS )
121(A:6918:THR )
122(A:6919:ALA )
123(A:6920:ASN )
124(A:6921:LYS )
125(A:6922:TRP )
126(A:6923:ASP )
127(A:6924:LEU )
128(A:6925:ILE )
129(A:6926:ILE )
130(A:6927:SER )
131(A:6928:ASP )
132(A:6929:MET )
133(A:6930:TYR )
134(A:6931:ASP )
135(A:6932:PRO )
136(A:6933:LYS )
137(A:6934:THR )
138(A:6935:LYS )
139(A:6936:ASN )
140(A:6937:VAL )
141(A:6938:THR )
142(A:6939:LYS )
143(A:6940:GLU )
144(A:6941:ASN )
145(A:6942:ASP )
146(A:6943:SER )
147(A:6944:LYS )
148(A:6945:GLU )
149(A:6946:GLY )
150(A:6947:PHE )
151(A:6948:PHE )
152(A:6949:THR )
153(A:6950:TYR )
154(A:6951:ILE )
155(A:6952:CYS )
156(A:6953:GLY )
157(A:6954:PHE )
158(A:6955:ILE )
159(A:6956:GLN )
160(A:6957:GLN )
161(A:6958:LYS )
162(A:6959:LEU )
163(A:6960:ALA )
164(A:6961:LEU )
165(A:6962:GLY )
166(A:6963:GLY )
167(A:6964:SER )
168(A:6965:VAL )
169(A:6966:ALA )
170(A:6967:ILE )
171(A:6968:LYS )
172(A:6969:ILE )
173(A:6970:THR )
174(A:6971:GLU )
175(A:6972:HIS )
176(A:6973:SER )
177(A:6974:TRP )
178(A:6975:ASN )
179(A:6976:ALA )
180(A:6977:ASP )
181(A:6978:LEU )
182(A:6979:TYR )
183(A:6980:LYS )
184(A:6981:LEU )
185(A:6982:MET )
186(A:6983:GLY )
187(A:6984:HIS )
188(A:6985:PHE )
189(A:6986:ALA )
190(A:6987:TRP )
191(A:6988:TRP )
192(A:6989:THR )
193(A:6990:ALA )
194(A:6991:PHE )
195(A:6992:VAL )
196(A:6993:THR )
197(A:6994:ASN )
198(A:6995:VAL )
199(A:6996:ASN )
200(A:6997:ALA )
201(A:6998:SER )
202(A:6999:SER )
203(A:7000:SER )
204(A:7001:GLU )
205(A:7002:ALA )
206(A:7003:PHE )
207(A:7004:LEU )
208(A:7005:ILE )
209(A:7006:GLY )
210(A:7007:CYS )
211(A:7008:ASN )
212(A:7009:TYR )
213(A:7010:LEU )
214(A:7011:GLY )
215(A:7012:LYS )
216(A:7013:PRO )
217(A:7014:ARG )
218(A:7015:GLU )
219(A:7016:GLN )
220(A:7017:ILE )
221(A:7018:ASP )
222(A:7019:GLY )
223(A:7020:TYR )
224(A:7021:VAL )
225(A:7022:MET )
226(A:7023:HIS )
227(A:7024:ALA )
228(A:7025:ASN )
229(A:7026:TYR )
230(A:7027:ILE )
231(A:7028:PHE )
232(A:7029:TRP )
233(A:7030:ARG )
234(A:7031:ASN )
235(A:7032:THR )
236(A:7033:ASN )
237(A:7034:PRO )
238(A:7035:ILE )
239(A:7036:GLN )
240(A:7037:LEU )
241(A:7038:SER )
242(A:7039:SER )
243(A:7040:TYR )
244(A:7041:SER )
245(A:7042:LEU )
246(A:7043:PHE )
247(A:7044:ASP )
248(A:7045:MET )
249(A:7046:SER )
250(A:7047:LYS )
251(A:7048:PHE )
252(A:7049:PRO )
253(A:7050:LEU )
254(A:7051:LYS )
255(A:7052:LEU )
256(A:7053:ARG )
257(A:7054:GLY )
258(A:7055:THR )
259(A:7056:ALA )
260(A:7057:VAL )
261(A:7058:MET )
262(A:7059:SER )
263(A:7060:LEU )
264(A:7061:LYS )
265(A:7062:GLU )
266(A:7063:GLY )
267(A:7064:GLN )
268(A:7065:ILE )
269(A:7066:ASN )
270(A:7067:ASP )
271(A:7068:MET )
272(A:7069:ILE )
273(A:7070:LEU )
274(A:7071:SER )
275(A:7072:LEU )
276(A:7073:LEU )
277(A:7074:SER )
278(A:7075:LYS )
279(A:7076:GLY )
280(A:7077:ARG )
281(A:7078:LEU )
282(A:7079:ILE )
283(A:7080:ILE )
284(A:7081:ARG )
285(A:7082:GLU )
286(A:7083:ASN )
287(A:7084:ASN )
288(A:7085:ARG )
289(A:7086:VAL )
290(A:7087:VAL )
291(A:7088:ILE )
292(A:7089:SER )
293(A:7090:SER )
294(A:7091:ASP )
295(A:7092:VAL )
296(A:7093:LEU )
297(A:7094:VAL )
298(A:7095:ASN )
299(A:7096:ASN )
300(B:4271:ALA )
301(B:4272:PHE )
302(B:4273:ALA )
303(B:4274:VAL )
304(B:4275:ASP )
305(B:4276:ALA )
306(B:4277:ALA )
307(B:4278:LYS )
308(B:4279:ALA )
309(B:4280:TYR )
310(B:4281:LYS )
311(B:4282:ASP )
312(B:4283:TYR )
313(B:4284:LEU )
314(B:4285:ALA )
315(B:4286:SER )
316(B:4287:GLY )
317(B:4288:GLY )
318(B:4289:GLN )
319(B:4290:PRO )
320(B:4291:ILE )
321(B:4292:THR )
322(B:4293:ASN )
323(B:4294:CYS )
324(B:4295:VAL )
325(B:4296:LYS )
326(B:4297:MET )
327(B:4298:LEU )
328(B:4299:CYS )
329(B:4300:THR )
330(B:4301:HIS )
331(B:4302:THR )
332(B:4303:GLY )
333(B:4304:THR )
334(B:4305:GLY )
335(B:4306:GLN )
336(B:4307:ALA )
337(B:4308:ILE )
338(B:4309:THR )
339(B:4310:VAL )
340(B:4311:THR )
341(B:4312:PRO )
342(B:4313:GLU )
343(B:4314:ALA )
344(B:4315:ASN )
345(B:4316:MET )
346(B:4317:ASP )
347(B:4318:GLN )
348(B:4319:GLU )
349(B:4320:SER )
350(B:4321:PHE )
351(B:4322:GLY )
352(B:4323:GLY )
353(B:4324:ALA )
354(B:4325:SER )
355(B:4326:CYS )
356(B:4327:CYS )
357(B:4328:LEU )
358(B:4329:TYR )
359(B:4330:CYS )
360(B:4331:ARG )
361(B:4332:CYS )
362(B:4333:HIS )
363(B:4334:ILE )
364(B:4335:ASP )
365(B:4336:HIS )
366(B:4337:PRO )
367(B:4338:ASN )
368(B:4339:PRO )
369(B:4340:LYS )
370(B:4341:GLY )
371(B:4342:PHE )
372(B:4343:CYS )
373(B:4344:ASP )
374(B:4345:LEU )
375(B:4346:LYS )
376(B:4347:GLY )
377(B:4348:LYS )
378(B:4349:TYR )
379(B:4350:VAL )
380(B:4351:GLN )
381(B:4352:ILE )
382(B:4353:PRO )
383(B:4354:THR )
384(B:4355:THR )
385(B:4356:CYS )
386(B:4357:ALA )
387(B:4358:ASN )
388(B:4359:ASP )
389(B:4360:PRO )
390(B:4361:VAL )
391(B:4362:GLY )
392(B:4363:PHE )
393(B:4364:THR )
394(B:4365:LEU )
395(B:4366:LYS )
396(B:4367:ASN )
397(B:4368:THR )
398(B:4369:VAL )
399(B:4370:CYS )
400(B:4371:THR )
401(B:4372:VAL )
402(B:4373:CYS )
403(B:4374:GLY )
404(B:4375:MET )
405(B:4376:TRP )
406(B:4377:LYS )
407(B:4378:GLY )
408(B:4379:TYR )
409(B:4380:GLY )
410(B:4381:CYS )
411(B:4382:SER )
412(B:4383:CYS )
413(B:4384:ASP )
414(B:4385:GLN )
415(B:4386:LEU )
416(A:7102:SAM )Lignad
417(A:7201:HOH )
418(A:7202:HOH )
419(A:7203:HOH )
420(A:7204:HOH )
421(A:7205:HOH )
422(A:7206:HOH )
423(A:7207:HOH )
424(A:7208:HOH )
425(A:7209:HOH )
426(A:7210:HOH )
427(A:7211:HOH )
428(A:7212:HOH )
429(A:7213:HOH )
430(A:7214:HOH )
431(A:7215:HOH )
432(A:7216:HOH )
433(A:7217:HOH )
434(A:7218:HOH )
435(A:7219:HOH )
436(A:7220:HOH )
437(A:7221:HOH )
438(A:7222:HOH )
439(A:7223:HOH )
440(A:7224:HOH )
441(A:7225:HOH )
442(A:7226:HOH )
443(A:7227:HOH )
444(A:7228:HOH )
445(A:7229:HOH )
446(A:7230:HOH )
447(A:7231:HOH )
448(A:7232:HOH )
449(A:7233:HOH )
450(A:7234:HOH )
451(A:7235:HOH )
452(A:7236:HOH )
453(A:7237:HOH )
454(A:7238:HOH )
455(A:7239:HOH )
456(A:7240:HOH )
457(A:7241:HOH )
458(A:7242:HOH )
459(A:7243:HOH )
460(A:7244:HOH )
461(A:7245:HOH )
462(A:7246:HOH )
463(A:7247:HOH )
464(A:7248:HOH )
465(A:7249:HOH )
466(A:7250:HOH )
467(A:7251:HOH )
468(A:7252:HOH )
469(A:7253:HOH )
470(A:7254:HOH )
471(A:7255:HOH )
472(A:7256:HOH )
473(A:7257:HOH )
474(A:7258:HOH )
475(A:7259:HOH )
476(A:7260:HOH )
477(A:7261:HOH )
478(A:7262:HOH )
479(A:7263:HOH )
480(A:7264:HOH )
481(A:7265:HOH )
482(A:7266:HOH )
483(A:7267:HOH )
484(A:7268:HOH )
485(A:7269:HOH )
486(A:7270:HOH )
487(A:7271:HOH )
488(A:7272:HOH )
489(A:7273:HOH )
490(A:7274:HOH )
491(A:7275:HOH )
492(A:7276:HOH )
493(A:7277:HOH )
494(A:7278:HOH )
495(A:7279:HOH )
496(A:7280:HOH )
497(A:7281:HOH )
498(A:7282:HOH )
499(A:7283:HOH )
500(A:7284:HOH )
501(A:7285:HOH )
502(A:7286:HOH )
503(A:7287:HOH )
504(A:7288:HOH )
505(A:7289:HOH )
506(A:7290:HOH )
507(A:7291:HOH )
508(A:7292:HOH )
509(A:7293:HOH )
510(A:7294:HOH )
511(A:7295:HOH )
512(A:7296:HOH )
513(A:7297:HOH )
514(A:7298:HOH )
515(A:7299:HOH )
516(A:7300:HOH )
517(A:7301:HOH )
518(A:7302:HOH )
519(A:7303:HOH )
520(A:7304:HOH )
521(A:7305:HOH )
522(A:7306:HOH )
523(A:7307:HOH )
524(A:7308:HOH )
525(A:7309:HOH )
526(A:7310:HOH )
527(A:7311:HOH )
528(A:7312:HOH )
529(A:7313:HOH )
530(A:7314:HOH )
531(A:7315:HOH )
532(A:7316:HOH )
533(A:7317:HOH )
534(A:7318:HOH )
535(A:7319:HOH )
536(A:7320:HOH )
537(A:7321:HOH )
538(A:7322:HOH )
539(A:7323:HOH )
540(A:7324:HOH )
541(A:7325:HOH )
542(A:7326:HOH )
543(A:7327:HOH )
544(A:7328:HOH )
545(A:7329:HOH )
546(A:7330:HOH )
547(A:7331:HOH )
548(A:7332:HOH )
549(A:7333:HOH )
550(A:7334:HOH )
551(A:7335:HOH )
552(A:7336:HOH )
553(A:7337:HOH )
554(A:7338:HOH )
555(A:7339:HOH )
556(A:7340:HOH )
557(A:7341:HOH )
558(A:7342:HOH )
559(A:7343:HOH )
560(A:7344:HOH )
561(A:7345:HOH )
562(A:7346:HOH )
563(A:7347:HOH )
564(A:7348:HOH )
565(A:7349:HOH )
566(A:7350:HOH )
567(A:7351:HOH )
568(A:7352:HOH )
569(A:7353:HOH )
570(A:7354:HOH )
571(A:7355:HOH )
572(A:7356:HOH )
573(A:7357:HOH )
574(A:7358:HOH )
575(A:7359:HOH )
576(A:7360:HOH )
577(A:7361:HOH )
578(A:7362:HOH )
579(A:7363:HOH )
580(A:7364:HOH )
581(A:7365:HOH )
582(A:7366:HOH )
583(A:7367:HOH )
584(A:7368:HOH )
585(A:7369:HOH )
586(A:7370:HOH )
587(A:7371:HOH )
588(A:7372:HOH )
589(A:7373:HOH )
590(A:7374:HOH )
591(A:7375:HOH )
592(A:7376:HOH )
593(A:7377:HOH )
594(A:7378:HOH )
595(A:7379:HOH )
596(A:7380:HOH )
597(A:7381:HOH )
598(A:7382:HOH )
599(A:7383:HOH )
600(A:7384:HOH )
601(A:7385:HOH )
602(A:7386:HOH )
603(A:7387:HOH )
604(A:7388:HOH )
605(A:7389:HOH )
606(A:7390:HOH )
607(A:7391:HOH )
608(A:7392:HOH )
609(A:7393:HOH )
610(A:7394:HOH )
611(A:7395:HOH )
612(A:7396:HOH )
613(A:7397:HOH )
614(A:7398:HOH )
615(A:7399:HOH )
616(A:7400:HOH )
617(A:7401:HOH )
618(A:7402:HOH )
619(A:7403:HOH )
620(A:7404:HOH )
621(A:7405:HOH )
622(A:7406:HOH )
623(A:7407:HOH )
624(A:7408:HOH )
625(A:7409:HOH )
626(A:7410:HOH )
627(A:7411:HOH )
628(A:7412:HOH )
629(A:7413:HOH )
630(A:7414:HOH )
631(A:7415:HOH )
632(A:7416:HOH )
633(A:7417:HOH )
634(A:7418:HOH )
635(A:7419:HOH )
636(A:7420:HOH )
637(A:7421:HOH )
638(A:7422:HOH )
639(A:7423:HOH )
640(A:7424:HOH )
641(A:7425:HOH )
642(A:7426:HOH )
643(A:7427:HOH )
644(A:7428:HOH )
645(A:7429:HOH )
646(A:7430:HOH )
647(A:7431:HOH )
648(A:7432:HOH )
649(A:7433:HOH )
650(A:7434:HOH )
651(A:7435:HOH )
652(A:7436:HOH )
653(A:7437:HOH )
654(A:7438:HOH )
655(A:7439:HOH )
656(A:7440:HOH )
657(A:7441:HOH )
658(A:7442:HOH )
659(A:7443:HOH )
660(A:7444:HOH )
661(A:7445:HOH )
662(A:7446:HOH )
663(A:7447:HOH )
664(A:7448:HOH )
665(A:7449:HOH )
666(A:7450:HOH )
667(A:7451:HOH )
668(A:7452:HOH )
669(A:7453:HOH )
670(A:7454:HOH )
671(A:7455:HOH )
672(A:7456:HOH )
673(A:7457:HOH )
674(A:7458:HOH )
675(A:7459:HOH )
676(A:7460:HOH )
677(A:7461:HOH )
678(A:7462:HOH )
679(A:7463:HOH )
680(A:7464:HOH )
681(A:7465:HOH )
682(A:7466:HOH )
683(A:7467:HOH )
684(A:7468:HOH )
685(A:7469:HOH )
686(A:7470:HOH )
687(A:7471:HOH )
688(A:7472:HOH )
689(A:7473:HOH )
690(A:7474:HOH )
691(A:7475:HOH )
692(A:7476:HOH )
693(A:7477:HOH )
694(A:7478:HOH )
695(A:7479:HOH )
696(A:7480:HOH )
697(A:7481:HOH )
698(A:7482:HOH )
699(A:7483:HOH )
700(A:7484:HOH )
701(A:7485:HOH )
702(A:7486:HOH )
703(A:7487:HOH )
704(A:7488:HOH )
705(A:7489:HOH )
706(A:7490:HOH )
707(A:7491:HOH )
708(A:7492:HOH )
709(A:7493:HOH )
710(A:7494:HOH )
711(A:7495:HOH )
712(A:7496:HOH )
713(A:7497:HOH )
714(A:7498:HOH )
715(A:7499:HOH )
716(A:7500:HOH )
717(A:7501:HOH )
718(A:7502:HOH )
719(A:7503:HOH )
720(A:7504:HOH )
721(A:7505:HOH )
722(A:7506:HOH )
723(A:7507:HOH )
724(A:7508:HOH )
725(A:7509:HOH )
726(A:7510:HOH )
727(A:7511:HOH )
728(A:7512:HOH )
729(A:7513:HOH )
730(A:7514:HOH )
731(A:7515:HOH )
732(A:7516:HOH )
733(A:7517:HOH )
734(A:7518:HOH )
735(A:7519:HOH )
736(A:7520:HOH )
737(A:7521:HOH )
738(A:7522:HOH )
739(A:7523:HOH )
740(A:7524:HOH )
741(A:7525:HOH )
742(A:7526:HOH )
743(A:7527:HOH )
744(A:7528:HOH )
745(A:7529:HOH )
746(A:7530:HOH )
747(A:7531:HOH )
748(A:7532:HOH )
749(A:7533:HOH )
750(A:7534:HOH )
751(A:7535:HOH )
752(A:7536:HOH )
753(A:7537:HOH )
754(B:4501:HOH )
755(B:4502:HOH )
756(B:4503:HOH )
757(B:4504:HOH )
758(B:4505:HOH )
759(B:4506:HOH )
760(B:4507:HOH )
761(B:4508:HOH )
762(B:4509:HOH )
763(B:4510:HOH )
764(B:4511:HOH )
765(B:4512:HOH )
766(B:4513:HOH )
767(B:4514:HOH )
768(B:4515:HOH )
769(B:4516:HOH )
770(B:4517:HOH )
771(B:4518:HOH )
772(B:4519:HOH )
773(B:4520:HOH )
774(B:4521:HOH )
775(B:4522:HOH )
776(B:4523:HOH )
777(B:4524:HOH )
778(B:4525:HOH )
779(B:4526:HOH )
780(B:4527:HOH )
781(B:4528:HOH )
782(B:4529:HOH )
783(B:4530:HOH )
784(B:4531:HOH )
785(B:4532:HOH )
786(B:4533:HOH )
787(B:4534:HOH )
788(B:4535:HOH )
789(B:4536:HOH )
790(B:4537:HOH )
791(B:4538:HOH )
792(B:4539:HOH )
793(B:4540:HOH )
794(B:4541:HOH )
795(B:4542:HOH )
796(B:4543:HOH )
797(B:4544:HOH )
798(B:4545:HOH )
799(B:4546:HOH )
800(B:4547:HOH )
801(B:4548:HOH )
802(B:4549:HOH )
803(B:4550:HOH )
804(B:4551:HOH )
805(B:4552:HOH )
806(B:4553:HOH )
807(B:4554:HOH )
808(B:4555:HOH )
809(B:4556:HOH )
810(B:4557:HOH )
811(B:4558:HOH )
812(B:4559:HOH )
813(B:4560:HOH )
814(B:4561:HOH )
815(B:4562:HOH )
816(B:4563:HOH )
817(B:4564:HOH )
818(B:4565:HOH )
819(B:4566:HOH )
820(B:4567:HOH )
821(B:4568:HOH )
822(B:4569:HOH )
823(B:4570:HOH )
824(B:4571:HOH )
825(B:4572:HOH )
826(B:4573:HOH )
827(B:4574:HOH )
828(B:4575:HOH )
829(B:4576:HOH )
830(B:4577:HOH )
831(B:4578:HOH )
832(B:4579:HOH )
833(B:4580:HOH )
834(B:4581:HOH )
835(B:4582:HOH )
836(B:4583:HOH )
837(B:4584:HOH )
838(B:4585:HOH )
839(B:4586:HOH )
840(B:4587:HOH )
841(B:4588:HOH )
842(B:4589:HOH )
843(B:4590:HOH )
844(B:4591:HOH )
845(B:4592:HOH )
846(B:4593:HOH )
847(B:4594:HOH )
848(B:4595:HOH )
849(B:4596:HOH )
850(B:4597:HOH )
851(B:4598:HOH )
852(B:4599:HOH )
853(B:4600:HOH )
854(B:4601:HOH )
855(B:4602:HOH )
856(B:4603:HOH )
857(B:4604:HOH )
858(B:4605:HOH )