FMO DATABASE

FMODB ID: GY6N1

Calculation Name: 4K7K-A-Xray372

Preferred Name:

Target Type:

Ligand Name:

ligand 3-letter code:

PDB ID: 4K7K

Chain ID: A

ChEMBL ID:

UniProt ID: P77211

Base Structure: X-ray

Registration Date: 2023-09-26

Reference: C. Watanabe, N. Tani, K. Kamisaka, T. Honma et al., Interaction energy analysis of Apo structure dataset on FMODB, To be published.

DOI:

IFIE MAP

IFIE Diagram

Modeling method

Optimization	MOE:Amber10:EHT
Restraint	OptH
Protonation	MOE:Protonate 3D
Complement	MOE:Structure Preparation
Water	No
Procedure	Auto-FMO protocol ver. 2.20220422

FMO calculation

FMO method	FMO2-MP2/6-31G(d)
Fragmentation	Auto
Number of fragment	380
LigandCharge
Software	ABINIT-MP - Open Ver. 1 Rev. 23Q2 / 20200603(SMP)

Total energy (hartree)

FMO2-HF: Electronic energy	-5733945.895729
FMO2-HF: Nuclear repulsion	5587206.408212
FMO2-HF: Total energy	-146739.487516
FMO2-MP2: Total energy	-147174.593457

3D Structure

Snapshot

Ligand structure

Ligand Interaction

Ligand binding energy

IFIE [kcal/mol]	PIEDA [kcal/mol]				Charge transfer value [e]
IFIE SUMIFIE SUM at MP2 level.	ESElectro static interaction energy.	EXExchange-repulsion energy.	CT+mixCharge transfer and mixing terms energy.	DI(MP2)Dispersion energy.	q(I=>J)Charge transfer value from I to J fragments.
N/A	N/A	N/A	N/A	N/A	N/A

Interactive mode: IFIE and PIEDA for fragment #1(A:32:TYR)

Summations of interaction energy for fragment #1(A:32:TYR)

IFIE [kcal/mol]	PIEDA [kcal/mol]				Charge transfer value [e]
IFIE SUMIFIE SUM at MP2 level.	ESElectro static interaction energy.	EXExchange-repulsion energy.	CT+mixCharge transfer and mixing terms energy.	DI(MP2)Dispersion energy.	q(I=>J)Charge transfer value from I to J fragments.
-5.482	-2.222	0.045	-1.154	-2.153	0.005

Interaction energy analysis for fragmet #1(A:32:TYR)

Snapshot

IFIE Diagram

Base fragment(s) of PIEDA/IFIE

Single fragment	Multi fragments
	Fragment list

Charge [e] FCHARGE : 0 / q_Mulliken : 0.043 / q_NPA : 0.010

Distance from base fragment(s) [Å]

Dist

Interaction energy by IFIE and PIEDA
[kcal/mol]

| Total | > | ES | > | EX | >
| CT+mix | > | DI(MP2) | >

Fragment charge [e]

FCHARGE q_Mulliken
q_NPA q(I=>J)

Residue

Res # RES

Sort

Graph Options

X Axis Label
Y Axis Max Y Axis Min
Display ES EX CT+mix DI(MP2)

frag_NumFragment number.	ChainChain species.	Res #Residue number.	RES3-letter code of amino acid residue, ligand and solvent molecule.	FCHARGEFormal charge [e].	q_MullikenFragment charge evaluated by Mulliken charge [e].	q_NPAFragment charge evaluated by natural population analysis(NPA) charge [e].	DISTDistance from Ligand [Å].	TotalIFIE at MP2 level [kcal/mol].	ESElectro static interaction energy by PIEDA [kcal/mol].	EXExchange-repulsion energy by PIEDA [kcal/mol].	CT+mixCharge transfer and mixing terms energy by PIEDA [kcal/mol].	DI(MP2)Dispersion energy by PIEDA [kcal/mol].	q(I=>J)Charge transfer value from I to J fragmens [e].
3	A	34	ASN	0	0.005	-0.017	3.072	-2.922	-0.228	0.043	-1.060	-1.678	0.005
4	A	35	ALA	0	-0.003	0.012	3.850	-0.521	-0.113	0.002	-0.081	-0.330	0.000
5	A	36	GLY	0	0.062	0.051	5.701	-0.041	-0.041	0.000	0.000	0.000	0.000
6	A	37	TRP	0	0.044	0.009	6.953	-0.348	-0.348	0.000	0.000	0.000	0.000
7	A	38	ARG	1	0.909	0.954	5.553	-0.750	-0.750	0.000	0.000	0.000	0.000
8	A	39	THR	0	-0.062	-0.039	8.821	-0.064	-0.064	0.000	0.000	0.000	0.000
9	A	40	PHE	0	-0.013	0.023	11.345	-0.028	-0.028	0.000	0.000	0.000	0.000
10	A	41	PHE	0	0.015	0.008	13.675	-0.040	-0.040	0.000	0.000	0.000	0.000
11	A	42	VAL	0	0.057	0.026	15.560	-0.002	-0.002	0.000	0.000	0.000	0.000
12	A	43	ASP	-1	-0.854	-0.926	18.094	0.200	0.200	0.000	0.000	0.000	0.000
13	A	44	ASN	0	0.010	-0.016	17.476	0.022	0.022	0.000	0.000	0.000	0.000
14	A	45	GLN	0	0.034	0.033	17.491	0.051	0.051	0.000	0.000	0.000	0.000
15	A	46	VAL	0	0.024	0.010	16.610	0.034	0.034	0.000	0.000	0.000	0.000
16	A	47	LYS	1	0.804	0.894	12.846	-0.168	-0.168	0.000	0.000	0.000	0.000
17	A	48	THR	0	-0.044	-0.009	13.379	0.076	0.076	0.000	0.000	0.000	0.000
18	A	49	LEU	0	0.028	0.011	15.019	0.052	0.052	0.000	0.000	0.000	0.000
19	A	50	ILE	0	0.000	0.003	10.877	0.050	0.050	0.000	0.000	0.000	0.000
20	A	51	SER	0	-0.039	-0.027	10.440	0.163	0.163	0.000	0.000	0.000	0.000
21	A	52	GLU	-1	-0.909	-0.952	11.468	0.495	0.495	0.000	0.000	0.000	0.000
22	A	53	ALA	0	0.047	0.018	14.305	0.022	0.022	0.000	0.000	0.000	0.000
23	A	54	LEU	0	-0.024	0.005	8.421	0.035	0.035	0.000	0.000	0.000	0.000
24	A	55	VAL	0	-0.032	0.001	10.747	0.046	0.046	0.000	0.000	0.000	0.000
25	A	56	ASN	0	-0.026	-0.013	12.090	-0.063	-0.063	0.000	0.000	0.000	0.000
26	A	57	ASN	0	-0.098	-0.088	13.705	-0.173	-0.173	0.000	0.000	0.000	0.000
27	A	58	ARG	1	0.944	0.977	11.578	-0.456	-0.456	0.000	0.000	0.000	0.000
28	A	59	ASP	-1	-0.862	-0.929	12.207	0.454	0.454	0.000	0.000	0.000	0.000
29	A	60	LEU	0	0.085	0.030	10.844	0.007	0.007	0.000	0.000	0.000	0.000
30	A	61	ARG	1	0.881	0.926	14.754	-0.238	-0.238	0.000	0.000	0.000	0.000
31	A	62	MET	0	-0.006	-0.016	18.154	-0.032	-0.032	0.000	0.000	0.000	0.000
32	A	63	ALA	0	0.017	0.015	15.143	-0.028	-0.028	0.000	0.000	0.000	0.000
33	A	64	THR	0	0.000	0.002	17.186	-0.033	-0.033	0.000	0.000	0.000	0.000
34	A	65	LEU	0	-0.024	-0.016	19.290	-0.038	-0.038	0.000	0.000	0.000	0.000
35	A	66	LYS	1	0.899	0.967	18.398	-0.471	-0.471	0.000	0.000	0.000	0.000
36	A	67	VAL	0	0.037	0.028	17.914	-0.024	-0.024	0.000	0.000	0.000	0.000
37	A	68	GLN	0	-0.045	-0.015	21.120	-0.026	-0.026	0.000	0.000	0.000	0.000
38	A	69	GLU	-1	-0.910	-0.968	24.201	0.161	0.161	0.000	0.000	0.000	0.000
39	A	70	ALA	0	-0.013	-0.007	23.114	-0.014	-0.014	0.000	0.000	0.000	0.000
40	A	71	ARG	1	0.886	0.935	23.072	-0.224	-0.224	0.000	0.000	0.000	0.000
41	A	72	ALA	0	-0.015	0.004	26.303	-0.019	-0.019	0.000	0.000	0.000	0.000
42	A	73	GLN	0	-0.004	-0.003	27.635	-0.007	-0.007	0.000	0.000	0.000	0.000
43	A	74	TYR	0	0.021	0.007	25.969	-0.010	-0.010	0.000	0.000	0.000	0.000
44	A	75	ARG	1	0.877	0.943	31.389	-0.107	-0.107	0.000	0.000	0.000	0.000
45	A	76	LEU	0	0.021	0.002	33.276	-0.008	-0.008	0.000	0.000	0.000	0.000
46	A	77	THR	0	-0.024	-0.005	35.222	-0.007	-0.007	0.000	0.000	0.000	0.000
47	A	78	ASP	-1	-0.916	-0.947	36.451	0.090	0.090	0.000	0.000	0.000	0.000
48	A	79	ALA	0	-0.101	-0.055	37.393	-0.006	-0.006	0.000	0.000	0.000	0.000
49	A	80	ASP	-1	-0.850	-0.926	39.082	0.093	0.093	0.000	0.000	0.000	0.000
50	A	81	ARG	1	0.868	0.952	40.837	-0.085	-0.085	0.000	0.000	0.000	0.000
51	A	113	ALA	0	0.002	-0.009	23.072	-0.005	-0.005	0.000	0.000	0.000	0.000
52	A	114	SER	0	0.035	0.009	24.646	0.010	0.010	0.000	0.000	0.000	0.000
53	A	115	PHE	0	0.056	0.038	16.072	-0.001	-0.001	0.000	0.000	0.000	0.000
54	A	116	ASP	-1	-0.787	-0.915	21.439	0.263	0.263	0.000	0.000	0.000	0.000
55	A	117	LEU	0	-0.061	-0.021	22.432	-0.002	-0.002	0.000	0.000	0.000	0.000
56	A	118	ASP	-1	-0.868	-0.921	22.926	0.080	0.080	0.000	0.000	0.000	0.000
57	A	119	PHE	0	-0.011	0.005	17.208	-0.007	-0.007	0.000	0.000	0.000	0.000
58	A	120	PHE	0	0.021	-0.021	21.265	-0.006	-0.006	0.000	0.000	0.000	0.000
59	A	121	GLY	0	-0.056	-0.027	24.063	-0.011	-0.011	0.000	0.000	0.000	0.000
60	A	122	ARG	1	0.777	0.848	20.373	-0.033	-0.033	0.000	0.000	0.000	0.000
61	A	123	LEU	0	0.021	0.006	20.930	-0.011	-0.011	0.000	0.000	0.000	0.000
62	A	124	LYS	1	0.943	0.966	24.259	-0.121	-0.121	0.000	0.000	0.000	0.000
63	A	125	ASN	0	-0.075	-0.026	27.834	-0.009	-0.009	0.000	0.000	0.000	0.000
64	A	126	MET	0	0.003	0.033	22.294	-0.011	-0.011	0.000	0.000	0.000	0.000
65	A	127	SER	0	0.000	0.007	27.696	0.013	0.013	0.000	0.000	0.000	0.000
66	A	128	GLU	-1	-0.756	-0.849	25.160	0.144	0.144	0.000	0.000	0.000	0.000
67	A	129	ALA	0	0.031	0.012	25.422	0.009	0.009	0.000	0.000	0.000	0.000
68	A	130	GLU	-1	-0.904	-0.961	24.665	0.022	0.022	0.000	0.000	0.000	0.000
69	A	131	ARG	1	0.826	0.906	22.573	-0.110	-0.110	0.000	0.000	0.000	0.000
70	A	132	GLN	0	-0.074	-0.066	20.809	0.020	0.020	0.000	0.000	0.000	0.000
71	A	133	ASN	0	-0.010	0.022	19.839	0.003	0.003	0.000	0.000	0.000	0.000
72	A	134	TYR	0	0.045	0.017	17.837	0.009	0.009	0.000	0.000	0.000	0.000
73	A	135	LEU	0	-0.080	-0.072	15.875	0.029	0.029	0.000	0.000	0.000	0.000
74	A	136	ALA	0	0.015	0.022	15.092	0.059	0.059	0.000	0.000	0.000	0.000
75	A	137	THR	0	-0.017	-0.004	14.292	-0.023	-0.023	0.000	0.000	0.000	0.000
76	A	138	GLU	-1	-0.893	-0.964	7.564	-1.327	-1.327	0.000	0.000	0.000	0.000
77	A	139	GLU	-1	-0.846	-0.940	10.922	-0.066	-0.066	0.000	0.000	0.000	0.000
78	A	140	ALA	0	0.013	0.039	12.978	0.116	0.116	0.000	0.000	0.000	0.000
79	A	141	GLN	0	0.041	0.010	9.325	-0.016	-0.016	0.000	0.000	0.000	0.000
80	A	142	ARG	1	0.862	0.954	6.870	0.794	0.794	0.000	0.000	0.000	0.000
81	A	143	ALA	0	0.021	-0.007	10.363	0.095	0.095	0.000	0.000	0.000	0.000
82	A	144	VAL	0	-0.005	-0.007	12.930	0.023	0.023	0.000	0.000	0.000	0.000
83	A	145	HIS	0	-0.009	0.001	6.933	0.268	0.268	0.000	0.000	0.000	0.000
84	A	146	ILE	0	-0.009	-0.007	10.698	-0.045	-0.045	0.000	0.000	0.000	0.000
85	A	147	LEU	0	0.016	0.029	13.061	-0.055	-0.055	0.000	0.000	0.000	0.000
86	A	148	LEU	0	-0.001	0.013	12.585	-0.057	-0.057	0.000	0.000	0.000	0.000
87	A	149	VAL	0	-0.028	-0.018	10.641	-0.069	-0.069	0.000	0.000	0.000	0.000
88	A	150	SER	0	-0.030	-0.027	13.802	-0.096	-0.096	0.000	0.000	0.000	0.000
89	A	151	ASN	0	-0.023	-0.035	17.081	-0.087	-0.087	0.000	0.000	0.000	0.000
90	A	152	VAL	0	0.013	0.018	15.433	-0.046	-0.046	0.000	0.000	0.000	0.000
91	A	153	ALA	0	-0.003	-0.010	16.989	-0.046	-0.046	0.000	0.000	0.000	0.000
92	A	154	GLN	0	-0.001	-0.005	18.736	-0.037	-0.037	0.000	0.000	0.000	0.000
93	A	155	SER	0	0.007	-0.004	21.466	-0.039	-0.039	0.000	0.000	0.000	0.000
94	A	156	TYR	0	0.026	0.009	21.008	-0.023	-0.023	0.000	0.000	0.000	0.000
95	A	157	PHE	0	0.010	0.000	20.462	-0.020	-0.020	0.000	0.000	0.000	0.000
96	A	158	ASN	0	0.069	0.055	24.758	-0.026	-0.026	0.000	0.000	0.000	0.000
97	A	159	GLN	0	0.012	0.023	25.947	-0.010	-0.010	0.000	0.000	0.000	0.000
98	A	160	GLN	0	-0.040	-0.039	25.490	-0.027	-0.027	0.000	0.000	0.000	0.000
99	A	161	LEU	0	-0.003	0.009	28.119	-0.012	-0.012	0.000	0.000	0.000	0.000
100	A	162	ALA	0	0.040	0.017	30.425	-0.011	-0.011	0.000	0.000	0.000	0.000
101	A	163	TYR	0	-0.027	-0.030	28.265	-0.013	-0.013	0.000	0.000	0.000	0.000
102	A	164	ALA	0	-0.024	0.001	32.265	-0.009	-0.009	0.000	0.000	0.000	0.000
103	A	165	GLN	0	-0.015	-0.017	34.067	-0.006	-0.006	0.000	0.000	0.000	0.000
104	A	166	LEU	0	0.001	0.008	36.010	-0.006	-0.006	0.000	0.000	0.000	0.000
105	A	167	GLN	0	0.000	0.005	36.759	-0.003	-0.003	0.000	0.000	0.000	0.000
106	A	168	ILE	0	-0.022	-0.013	37.862	-0.006	-0.006	0.000	0.000	0.000	0.000
107	A	169	ALA	0	0.003	0.016	40.240	-0.005	-0.005	0.000	0.000	0.000	0.000
108	A	170	GLU	-1	-0.889	-0.953	40.799	0.078	0.078	0.000	0.000	0.000	0.000
109	A	171	GLU	-1	-0.901	-0.962	41.434	0.063	0.063	0.000	0.000	0.000	0.000
110	A	172	THR	0	-0.035	-0.036	44.056	-0.004	-0.004	0.000	0.000	0.000	0.000
111	A	173	LEU	0	0.021	0.029	46.163	-0.004	-0.004	0.000	0.000	0.000	0.000
112	A	174	ARG	1	0.942	0.977	44.920	-0.061	-0.061	0.000	0.000	0.000	0.000
113	A	175	ASN	0	-0.057	-0.025	48.774	-0.004	-0.004	0.000	0.000	0.000	0.000
114	A	176	TYR	0	0.073	0.007	48.966	-0.004	-0.004	0.000	0.000	0.000	0.000
115	A	177	GLN	0	-0.019	-0.013	51.201	-0.001	-0.001	0.000	0.000	0.000	0.000
116	A	178	GLN	0	-0.032	-0.013	52.005	-0.002	-0.002	0.000	0.000	0.000	0.000
117	A	179	SER	0	-0.043	-0.024	54.688	-0.002	-0.002	0.000	0.000	0.000	0.000
118	A	180	TYR	0	0.012	-0.001	56.287	-0.002	-0.002	0.000	0.000	0.000	0.000
119	A	181	ALA	0	0.021	0.002	57.894	-0.001	-0.001	0.000	0.000	0.000	0.000
120	A	182	PHE	0	-0.040	-0.024	59.398	-0.001	-0.001	0.000	0.000	0.000	0.000
121	A	183	VAL	0	0.057	0.030	60.715	-0.001	-0.001	0.000	0.000	0.000	0.000
122	A	184	GLU	-1	-0.955	-0.972	62.209	0.033	0.033	0.000	0.000	0.000	0.000
123	A	185	LYS	1	0.956	0.988	60.755	-0.035	-0.035	0.000	0.000	0.000	0.000
124	A	186	GLN	0	0.023	-0.002	64.811	-0.001	-0.001	0.000	0.000	0.000	0.000
125	A	187	LEU	0	-0.029	-0.014	66.684	-0.001	-0.001	0.000	0.000	0.000	0.000
126	A	188	LEU	0	-0.073	-0.016	68.508	-0.001	-0.001	0.000	0.000	0.000	0.000
127	A	189	THR	0	-0.044	-0.023	70.586	-0.001	-0.001	0.000	0.000	0.000	0.000
128	A	190	GLY	0	-0.031	-0.001	72.032	-0.001	-0.001	0.000	0.000	0.000	0.000
129	A	191	SER	0	-0.029	-0.024	68.255	0.000	0.000	0.000	0.000	0.000	0.000
130	A	192	SER	0	-0.006	-0.001	65.404	0.000	0.000	0.000	0.000	0.000	0.000
131	A	193	ASN	0	0.041	0.016	66.213	0.000	0.000	0.000	0.000	0.000	0.000
132	A	194	VAL	0	0.088	0.033	65.904	0.001	0.001	0.000	0.000	0.000	0.000
133	A	195	LEU	0	0.016	0.005	63.564	0.001	0.001	0.000	0.000	0.000	0.000
134	A	196	ALA	0	0.005	0.009	62.129	0.001	0.001	0.000	0.000	0.000	0.000
135	A	197	LEU	0	-0.008	-0.005	60.938	0.001	0.001	0.000	0.000	0.000	0.000
136	A	198	GLU	-1	-0.910	-0.950	60.813	0.037	0.037	0.000	0.000	0.000	0.000
137	A	199	GLN	0	0.049	0.018	58.176	0.001	0.001	0.000	0.000	0.000	0.000
138	A	200	ALA	0	-0.026	-0.006	56.639	0.002	0.002	0.000	0.000	0.000	0.000
139	A	201	ARG	1	0.907	0.933	55.680	-0.035	-0.035	0.000	0.000	0.000	0.000
140	A	202	GLY	0	0.030	0.026	55.178	0.002	0.002	0.000	0.000	0.000	0.000
141	A	203	VAL	0	0.025	0.007	51.792	0.002	0.002	0.000	0.000	0.000	0.000
142	A	204	ILE	0	-0.021	0.033	50.601	0.003	0.003	0.000	0.000	0.000	0.000
143	A	205	GLU	-1	-0.870	-0.938	50.323	0.054	0.054	0.000	0.000	0.000	0.000
144	A	206	SER	0	-0.056	-0.024	49.024	0.003	0.003	0.000	0.000	0.000	0.000
145	A	207	THR	0	0.007	-0.032	45.912	0.003	0.003	0.000	0.000	0.000	0.000
146	A	208	ARG	1	0.876	0.921	45.492	-0.051	-0.051	0.000	0.000	0.000	0.000
147	A	209	SER	0	0.004	0.007	45.568	0.004	0.004	0.000	0.000	0.000	0.000
148	A	210	ASP	-1	-0.902	-0.949	42.203	0.072	0.072	0.000	0.000	0.000	0.000
149	A	211	ILE	0	0.006	0.010	41.033	0.006	0.006	0.000	0.000	0.000	0.000
150	A	212	ALA	0	0.017	0.016	40.431	0.006	0.006	0.000	0.000	0.000	0.000
151	A	213	LYS	1	0.867	0.923	38.242	-0.083	-0.083	0.000	0.000	0.000	0.000
152	A	214	ARG	1	0.840	0.924	36.762	-0.086	-0.086	0.000	0.000	0.000	0.000
153	A	215	GLN	0	0.018	0.010	35.719	0.005	0.005	0.000	0.000	0.000	0.000
154	A	216	GLY	0	0.006	0.005	35.902	0.007	0.007	0.000	0.000	0.000	0.000
155	A	217	GLU	-1	-0.810	-0.902	33.233	0.112	0.112	0.000	0.000	0.000	0.000
156	A	218	LEU	0	-0.023	-0.004	30.552	0.012	0.012	0.000	0.000	0.000	0.000
157	A	219	ALA	0	-0.031	-0.015	30.672	0.013	0.013	0.000	0.000	0.000	0.000
158	A	220	GLN	0	-0.022	-0.015	30.827	0.011	0.011	0.000	0.000	0.000	0.000
159	A	221	ALA	0	0.036	0.023	26.938	0.013	0.013	0.000	0.000	0.000	0.000
160	A	222	ASN	0	0.031	0.005	26.079	0.030	0.030	0.000	0.000	0.000	0.000
161	A	223	ASN	0	-0.017	0.002	26.373	0.025	0.025	0.000	0.000	0.000	0.000
162	A	224	ALA	0	0.010	0.011	24.342	0.016	0.016	0.000	0.000	0.000	0.000
163	A	225	LEU	0	-0.007	-0.016	20.979	0.033	0.033	0.000	0.000	0.000	0.000
164	A	226	GLN	0	0.030	0.007	21.644	0.047	0.047	0.000	0.000	0.000	0.000
165	A	227	LEU	0	-0.035	0.010	22.659	0.023	0.023	0.000	0.000	0.000	0.000
166	A	228	LEU	0	-0.051	-0.026	18.274	0.034	0.034	0.000	0.000	0.000	0.000
167	A	229	LEU	0	-0.024	-0.016	17.319	0.073	0.073	0.000	0.000	0.000	0.000
168	A	230	GLY	0	-0.020	-0.001	18.831	0.028	0.028	0.000	0.000	0.000	0.000
169	A	231	SER	0	-0.025	-0.036	20.996	-0.011	-0.011	0.000	0.000	0.000	0.000
170	A	232	TYR	0	-0.050	-0.026	20.504	-0.032	-0.032	0.000	0.000	0.000	0.000
171	A	233	GLY	0	0.056	0.060	20.927	0.007	0.007	0.000	0.000	0.000	0.000
172	A	234	LYS	1	0.924	0.952	21.657	-0.215	-0.215	0.000	0.000	0.000	0.000
173	A	235	LEU	0	0.008	0.004	22.672	0.014	0.014	0.000	0.000	0.000	0.000
174	A	236	PRO	0	-0.058	-0.012	22.600	-0.018	-0.018	0.000	0.000	0.000	0.000
175	A	237	GLN	0	0.034	0.018	25.308	-0.002	-0.002	0.000	0.000	0.000	0.000
176	A	238	ALA	0	0.033	0.013	27.799	0.007	0.007	0.000	0.000	0.000	0.000
177	A	239	GLN	0	0.003	-0.004	25.277	0.001	0.001	0.000	0.000	0.000	0.000
178	A	240	THR	0	-0.045	-0.022	28.706	-0.003	-0.003	0.000	0.000	0.000	0.000
179	A	241	VAL	0	0.015	0.010	29.886	0.002	0.002	0.000	0.000	0.000	0.000
180	A	242	ASN	0	0.036	0.015	31.013	-0.010	-0.010	0.000	0.000	0.000	0.000
181	A	243	SER	0	0.008	-0.008	32.164	0.002	0.002	0.000	0.000	0.000	0.000
182	A	244	ASP	-1	-0.886	-0.920	33.975	0.052	0.052	0.000	0.000	0.000	0.000
183	A	245	SER	0	-0.116	-0.081	28.423	-0.003	-0.003	0.000	0.000	0.000	0.000
184	A	246	LEU	0	-0.001	0.019	28.733	0.008	0.008	0.000	0.000	0.000	0.000
185	A	247	GLN	0	0.034	0.029	28.424	0.007	0.007	0.000	0.000	0.000	0.000
186	A	248	SER	0	-0.020	-0.001	23.401	0.003	0.003	0.000	0.000	0.000	0.000
187	A	249	VAL	0	0.013	0.014	19.363	-0.009	-0.009	0.000	0.000	0.000	0.000
188	A	250	LYS	1	0.964	0.967	21.179	-0.023	-0.023	0.000	0.000	0.000	0.000
189	A	251	LEU	0	-0.074	0.021	16.942	0.008	0.008	0.000	0.000	0.000	0.000
190	A	252	PRO	0	0.029	0.025	13.981	-0.008	-0.008	0.000	0.000	0.000	0.000
191	A	253	ALA	0	0.037	0.029	16.984	0.000	0.000	0.000	0.000	0.000	0.000
192	A	254	GLY	0	-0.015	-0.006	18.005	-0.007	-0.007	0.000	0.000	0.000	0.000
193	A	255	LEU	0	-0.037	-0.009	13.248	-0.013	-0.013	0.000	0.000	0.000	0.000
194	A	256	SER	0	0.082	0.035	13.655	-0.014	-0.014	0.000	0.000	0.000	0.000
195	A	257	SER	0	0.018	-0.024	14.411	-0.006	-0.006	0.000	0.000	0.000	0.000
196	A	258	GLN	0	0.048	0.013	11.772	0.032	0.032	0.000	0.000	0.000	0.000
197	A	259	ILE	0	-0.016	0.004	9.000	-0.075	-0.075	0.000	0.000	0.000	0.000
198	A	260	LEU	0	0.011	0.001	11.120	-0.010	-0.010	0.000	0.000	0.000	0.000
199	A	261	LEU	0	-0.038	-0.015	10.906	0.011	0.011	0.000	0.000	0.000	0.000
200	A	262	GLN	0	-0.141	-0.051	7.985	-0.169	-0.169	0.000	0.000	0.000	0.000
201	A	263	ARG	1	0.782	0.863	9.954	0.140	0.140	0.000	0.000	0.000	0.000
202	A	264	PRO	0	0.014	0.005	12.668	-0.069	-0.069	0.000	0.000	0.000	0.000
203	A	265	ASP	-1	-0.803	-0.884	14.368	-0.078	-0.078	0.000	0.000	0.000	0.000
204	A	266	ILE	0	0.042	0.020	14.433	-0.014	-0.014	0.000	0.000	0.000	0.000
205	A	267	MET	0	-0.041	-0.011	9.416	-0.006	-0.006	0.000	0.000	0.000	0.000
206	A	268	GLU	-1	-0.784	-0.857	14.070	-0.038	-0.038	0.000	0.000	0.000	0.000
207	A	269	ALA	0	-0.038	-0.024	17.179	0.002	0.002	0.000	0.000	0.000	0.000
208	A	270	GLU	-1	-0.738	-0.828	13.916	-0.488	-0.488	0.000	0.000	0.000	0.000
209	A	271	HIS	0	0.031	0.015	14.826	0.028	0.028	0.000	0.000	0.000	0.000
210	A	272	ALA	0	-0.022	-0.012	17.812	0.018	0.018	0.000	0.000	0.000	0.000
211	A	273	LEU	0	-0.011	-0.001	19.541	0.012	0.012	0.000	0.000	0.000	0.000
212	A	274	MET	0	-0.031	-0.018	15.595	-0.007	-0.007	0.000	0.000	0.000	0.000
213	A	275	ALA	0	-0.023	0.006	20.338	0.015	0.015	0.000	0.000	0.000	0.000
214	A	276	ALA	0	-0.058	-0.015	22.874	0.019	0.019	0.000	0.000	0.000	0.000
215	A	277	ASN	0	-0.067	-0.043	23.650	-0.004	-0.004	0.000	0.000	0.000	0.000
216	A	278	ALA	0	-0.001	0.005	21.667	0.008	0.008	0.000	0.000	0.000	0.000
217	A	279	ASN	0	-0.015	-0.005	20.858	-0.049	-0.049	0.000	0.000	0.000	0.000
218	A	280	ILE	0	0.062	0.019	15.291	0.013	0.013	0.000	0.000	0.000	0.000
219	A	281	GLY	0	-0.010	0.001	17.607	0.005	0.005	0.000	0.000	0.000	0.000
220	A	282	ALA	0	0.006	-0.008	18.437	0.018	0.018	0.000	0.000	0.000	0.000
221	A	283	ALA	0	0.025	0.013	20.095	0.023	0.023	0.000	0.000	0.000	0.000
222	A	284	ARG	1	0.825	0.875	11.459	0.625	0.625	0.000	0.000	0.000	0.000
223	A	285	ALA	0	-0.025	-0.006	19.045	0.019	0.019	0.000	0.000	0.000	0.000
224	A	286	ALA	0	-0.030	0.003	21.404	0.018	0.018	0.000	0.000	0.000	0.000
225	A	287	PHE	0	-0.002	-0.027	22.239	0.016	0.016	0.000	0.000	0.000	0.000
226	A	288	PHE	0	-0.013	-0.002	15.550	0.010	0.010	0.000	0.000	0.000	0.000
227	A	289	PRO	0	-0.010	0.004	20.016	-0.010	-0.010	0.000	0.000	0.000	0.000
228	A	290	SER	0	0.008	0.032	17.495	-0.004	-0.004	0.000	0.000	0.000	0.000
229	A	291	ILE	0	0.012	0.012	19.237	0.011	0.011	0.000	0.000	0.000	0.000
230	A	292	SER	0	0.020	0.018	18.543	-0.009	-0.009	0.000	0.000	0.000	0.000
231	A	293	LEU	0	0.013	0.022	16.344	0.007	0.007	0.000	0.000	0.000	0.000
232	A	294	THR	0	-0.013	-0.015	18.983	0.008	0.008	0.000	0.000	0.000	0.000
233	A	295	SER	0	0.019	0.012	21.434	-0.009	-0.009	0.000	0.000	0.000	0.000
234	A	296	GLY	0	0.029	0.005	22.705	0.000	0.000	0.000	0.000	0.000	0.000
235	A	297	ILE	0	-0.037	-0.008	23.920	0.004	0.004	0.000	0.000	0.000	0.000
236	A	298	SER	0	0.018	-0.040	21.019	-0.004	-0.004	0.000	0.000	0.000	0.000
237	A	299	THR	0	-0.030	-0.025	22.922	0.007	0.007	0.000	0.000	0.000	0.000
238	A	300	ALA	0	0.108	0.041	23.977	-0.005	-0.005	0.000	0.000	0.000	0.000
239	A	301	SER	0	-0.066	-0.041	22.824	0.002	0.002	0.000	0.000	0.000	0.000
240	A	302	SER	0	0.070	0.012	25.152	0.003	0.003	0.000	0.000	0.000	0.000
241	A	303	ASP	-1	-0.887	-0.935	24.212	-0.070	-0.070	0.000	0.000	0.000	0.000
242	A	304	LEU	0	-0.019	-0.009	22.117	-0.002	-0.002	0.000	0.000	0.000	0.000
243	A	305	SER	0	-0.042	-0.029	24.894	0.004	0.004	0.000	0.000	0.000	0.000
244	A	306	SER	0	-0.038	-0.016	28.185	0.000	0.000	0.000	0.000	0.000	0.000
245	A	307	LEU	0	-0.005	0.020	23.884	-0.002	-0.002	0.000	0.000	0.000	0.000
246	A	308	PHE	0	-0.023	0.000	25.585	0.000	0.000	0.000	0.000	0.000	0.000
247	A	309	ASN	0	0.003	0.011	30.715	0.004	0.004	0.000	0.000	0.000	0.000
248	A	310	ALA	0	0.039	0.009	34.474	0.004	0.004	0.000	0.000	0.000	0.000
249	A	311	SER	0	-0.085	-0.046	36.450	0.001	0.001	0.000	0.000	0.000	0.000
250	A	312	SER	0	0.034	0.004	36.326	0.002	0.002	0.000	0.000	0.000	0.000
251	A	313	GLY	0	-0.019	0.000	32.722	0.002	0.002	0.000	0.000	0.000	0.000
252	A	314	MET	0	-0.023	-0.011	31.740	-0.002	-0.002	0.000	0.000	0.000	0.000
253	A	315	TRP	0	0.035	0.015	23.578	0.001	0.001	0.000	0.000	0.000	0.000
254	A	316	ASN	0	-0.002	-0.042	29.822	0.001	0.001	0.000	0.000	0.000	0.000
255	A	317	PHE	0	-0.067	-0.014	24.740	-0.001	-0.001	0.000	0.000	0.000	0.000
256	A	318	ILE	0	-0.001	0.003	28.665	0.002	0.002	0.000	0.000	0.000	0.000
257	A	319	PRO	0	0.016	0.029	26.776	-0.003	-0.003	0.000	0.000	0.000	0.000
258	A	320	LYS	1	0.945	0.965	27.892	0.107	0.107	0.000	0.000	0.000	0.000
259	A	321	ILE	0	0.009	-0.005	27.305	-0.009	-0.009	0.000	0.000	0.000	0.000
260	A	322	GLU	-1	-0.956	-0.970	27.463	-0.109	-0.109	0.000	0.000	0.000	0.000
261	A	323	ILE	0	-0.026	-0.017	25.203	0.004	0.004	0.000	0.000	0.000	0.000
262	A	324	PRO	0	-0.026	-0.021	26.900	-0.007	-0.007	0.000	0.000	0.000	0.000
263	A	325	ILE	0	0.027	0.021	23.566	-0.009	-0.009	0.000	0.000	0.000	0.000
264	A	326	PHE	0	0.019	0.021	25.164	-0.017	-0.017	0.000	0.000	0.000	0.000
265	A	327	ASN	0	-0.021	-0.008	27.534	0.010	0.010	0.000	0.000	0.000	0.000
266	A	328	ALA	0	0.070	0.031	29.918	0.005	0.005	0.000	0.000	0.000	0.000
267	A	329	GLY	0	-0.009	0.003	31.199	0.003	0.003	0.000	0.000	0.000	0.000
268	A	330	ARG	1	0.926	0.945	32.072	0.095	0.095	0.000	0.000	0.000	0.000
269	A	331	ASN	0	0.013	0.000	34.335	0.004	0.004	0.000	0.000	0.000	0.000
270	A	332	GLN	0	-0.039	-0.019	37.308	0.001	0.001	0.000	0.000	0.000	0.000
271	A	333	ALA	0	0.065	0.038	39.139	0.004	0.004	0.000	0.000	0.000	0.000
272	A	334	ASN	0	-0.031	-0.024	36.608	0.000	0.000	0.000	0.000	0.000	0.000
273	A	335	LEU	0	0.067	0.044	36.256	-0.003	-0.003	0.000	0.000	0.000	0.000
274	A	336	ASP	-1	-0.829	-0.915	35.851	-0.063	-0.063	0.000	0.000	0.000	0.000
275	A	337	ILE	0	-0.069	-0.029	34.059	-0.001	-0.001	0.000	0.000	0.000	0.000
276	A	338	ALA	0	0.018	-0.005	31.878	-0.003	-0.003	0.000	0.000	0.000	0.000
277	A	339	GLU	-1	-0.848	-0.927	31.221	-0.093	-0.093	0.000	0.000	0.000	0.000
278	A	340	ILE	0	-0.021	-0.001	31.980	-0.003	-0.003	0.000	0.000	0.000	0.000
279	A	341	ARG	1	0.868	0.925	28.830	0.064	0.064	0.000	0.000	0.000	0.000
280	A	342	GLN	0	0.046	0.025	27.670	-0.003	-0.003	0.000	0.000	0.000	0.000
281	A	343	GLN	0	0.000	-0.003	27.781	-0.004	-0.004	0.000	0.000	0.000	0.000
282	A	344	GLN	0	-0.003	0.000	28.952	-0.004	-0.004	0.000	0.000	0.000	0.000
283	A	345	SER	0	-0.026	0.002	23.686	-0.003	-0.003	0.000	0.000	0.000	0.000
284	A	346	VAL	0	0.045	0.017	24.067	-0.010	-0.010	0.000	0.000	0.000	0.000
285	A	347	VAL	0	0.018	0.015	25.424	0.000	0.000	0.000	0.000	0.000	0.000
286	A	348	ASN	0	-0.040	-0.032	22.243	0.021	0.021	0.000	0.000	0.000	0.000
287	A	349	TYR	0	-0.062	-0.065	16.891	0.013	0.013	0.000	0.000	0.000	0.000
288	A	350	GLU	-1	-0.887	-0.957	22.034	-0.093	-0.093	0.000	0.000	0.000	0.000
289	A	351	GLN	0	-0.048	-0.024	24.416	0.009	0.009	0.000	0.000	0.000	0.000
290	A	352	LYS	1	0.931	0.966	20.238	0.046	0.046	0.000	0.000	0.000	0.000
291	A	353	ILE	0	0.015	0.023	19.293	0.009	0.009	0.000	0.000	0.000	0.000
292	A	354	GLN	0	-0.030	-0.015	21.134	0.019	0.019	0.000	0.000	0.000	0.000
293	A	355	ASN	0	-0.012	-0.001	22.192	0.014	0.014	0.000	0.000	0.000	0.000
294	A	356	ALA	0	-0.009	0.015	18.374	0.015	0.015	0.000	0.000	0.000	0.000
295	A	357	PHE	0	0.002	-0.022	18.896	0.018	0.018	0.000	0.000	0.000	0.000
296	A	358	LYS	1	0.924	0.966	21.842	-0.004	-0.004	0.000	0.000	0.000	0.000
297	A	359	GLU	-1	-0.856	-0.931	21.338	0.061	0.061	0.000	0.000	0.000	0.000
298	A	360	VAL	0	-0.014	-0.010	18.393	0.014	0.014	0.000	0.000	0.000	0.000
299	A	361	ALA	0	-0.017	-0.008	21.500	0.007	0.007	0.000	0.000	0.000	0.000
300	A	362	ASP	-1	-0.833	-0.916	24.836	0.025	0.025	0.000	0.000	0.000	0.000
301	A	363	ALA	0	-0.002	0.001	22.621	0.006	0.006	0.000	0.000	0.000	0.000
302	A	364	LEU	0	-0.034	-0.028	21.231	0.006	0.006	0.000	0.000	0.000	0.000
303	A	365	ALA	0	0.002	0.003	24.771	0.001	0.001	0.000	0.000	0.000	0.000
304	A	366	LEU	0	-0.018	0.001	27.490	0.001	0.001	0.000	0.000	0.000	0.000
305	A	367	ARG	1	0.810	0.891	20.876	-0.080	-0.080	0.000	0.000	0.000	0.000
306	A	368	GLN	0	-0.065	-0.022	26.999	0.000	0.000	0.000	0.000	0.000	0.000
307	A	369	SER	0	0.032	0.015	29.221	0.001	0.001	0.000	0.000	0.000	0.000
308	A	370	LEU	0	0.004	-0.003	28.699	0.000	0.000	0.000	0.000	0.000	0.000
309	A	371	ASN	0	0.027	0.005	26.437	0.007	0.007	0.000	0.000	0.000	0.000
310	A	372	ASP	-1	-0.880	-0.929	30.697	0.030	0.030	0.000	0.000	0.000	0.000
311	A	373	GLN	0	-0.067	-0.043	34.130	0.001	0.001	0.000	0.000	0.000	0.000
312	A	374	ILE	0	-0.004	-0.005	30.457	0.000	0.000	0.000	0.000	0.000	0.000
313	A	375	SER	0	-0.012	0.005	34.032	-0.001	-0.001	0.000	0.000	0.000	0.000
314	A	376	ALA	0	-0.035	-0.013	35.418	-0.002	-0.002	0.000	0.000	0.000	0.000
315	A	377	GLN	0	0.036	0.006	37.310	-0.001	-0.001	0.000	0.000	0.000	0.000
316	A	378	GLN	0	-0.015	-0.027	33.013	-0.003	-0.003	0.000	0.000	0.000	0.000
317	A	379	ARG	1	0.953	0.988	38.136	-0.030	-0.030	0.000	0.000	0.000	0.000
318	A	380	TYR	0	-0.029	-0.018	41.048	-0.003	-0.003	0.000	0.000	0.000	0.000
319	A	381	LEU	0	0.053	0.019	38.721	-0.001	-0.001	0.000	0.000	0.000	0.000
320	A	382	ALA	0	0.047	0.032	41.266	-0.001	-0.001	0.000	0.000	0.000	0.000
321	A	383	SER	0	-0.031	-0.017	42.968	-0.002	-0.002	0.000	0.000	0.000	0.000
322	A	384	LEU	0	0.004	0.006	44.792	-0.001	-0.001	0.000	0.000	0.000	0.000
323	A	385	GLN	0	0.006	-0.006	40.379	-0.002	-0.002	0.000	0.000	0.000	0.000
324	A	386	ILE	0	-0.022	-0.004	45.989	-0.001	-0.001	0.000	0.000	0.000	0.000
325	A	387	THR	0	-0.039	-0.033	48.347	-0.002	-0.002	0.000	0.000	0.000	0.000
326	A	388	LEU	0	0.009	0.021	47.617	-0.001	-0.001	0.000	0.000	0.000	0.000
327	A	389	GLN	0	-0.019	-0.011	45.887	-0.002	-0.002	0.000	0.000	0.000	0.000
328	A	390	ARG	1	0.959	0.975	51.108	-0.029	-0.029	0.000	0.000	0.000	0.000
329	A	391	ALA	0	0.057	0.034	53.822	-0.001	-0.001	0.000	0.000	0.000	0.000
330	A	392	ARG	1	0.884	0.933	47.922	-0.044	-0.044	0.000	0.000	0.000	0.000
331	A	393	ALA	0	0.011	0.008	54.964	0.000	0.000	0.000	0.000	0.000	0.000
332	A	394	LEU	0	0.011	0.000	57.032	-0.001	-0.001	0.000	0.000	0.000	0.000
333	A	395	TYR	0	-0.013	0.008	57.858	-0.001	-0.001	0.000	0.000	0.000	0.000
334	A	396	GLN	0	-0.035	-0.020	56.970	-0.001	-0.001	0.000	0.000	0.000	0.000
335	A	397	HIS	0	-0.087	-0.040	60.450	-0.001	-0.001	0.000	0.000	0.000	0.000
336	A	398	GLY	0	-0.014	0.000	63.233	-0.001	-0.001	0.000	0.000	0.000	0.000
337	A	399	ALA	0	-0.036	-0.008	62.427	0.000	0.000	0.000	0.000	0.000	0.000
338	A	400	VAL	0	-0.020	-0.004	58.632	0.000	0.000	0.000	0.000	0.000	0.000
339	A	401	SER	0	0.065	0.024	61.471	0.001	0.001	0.000	0.000	0.000	0.000
340	A	402	TYR	0	0.060	0.014	54.510	0.001	0.001	0.000	0.000	0.000	0.000
341	A	403	LEU	0	0.004	-0.010	57.176	0.001	0.001	0.000	0.000	0.000	0.000
342	A	404	GLU	-1	-0.891	-0.936	56.650	0.031	0.031	0.000	0.000	0.000	0.000
343	A	405	VAL	0	-0.041	-0.015	53.360	0.001	0.001	0.000	0.000	0.000	0.000
344	A	406	LEU	0	-0.056	-0.028	52.540	0.002	0.002	0.000	0.000	0.000	0.000
345	A	407	ASP	-1	-0.866	-0.933	51.779	0.038	0.038	0.000	0.000	0.000	0.000
346	A	408	ALA	0	0.046	0.018	51.522	0.001	0.001	0.000	0.000	0.000	0.000
347	A	409	GLU	-1	-0.904	-0.960	47.307	0.050	0.050	0.000	0.000	0.000	0.000
348	A	410	ARG	1	0.885	0.957	47.094	-0.039	-0.039	0.000	0.000	0.000	0.000
349	A	411	SER	0	0.026	0.019	46.896	0.002	0.002	0.000	0.000	0.000	0.000
350	A	412	LEU	0	-0.042	-0.016	43.385	0.001	0.001	0.000	0.000	0.000	0.000
351	A	413	PHE	0	-0.007	-0.011	42.807	0.003	0.003	0.000	0.000	0.000	0.000
352	A	414	ALA	0	0.048	0.023	41.945	0.004	0.004	0.000	0.000	0.000	0.000
353	A	415	THR	0	0.004	0.010	41.205	0.001	0.001	0.000	0.000	0.000	0.000
354	A	416	ARG	1	0.872	0.927	38.205	-0.067	-0.067	0.000	0.000	0.000	0.000
355	A	417	GLN	0	-0.002	-0.004	37.185	0.009	0.009	0.000	0.000	0.000	0.000
356	A	418	THR	0	-0.002	0.018	37.232	0.003	0.003	0.000	0.000	0.000	0.000
357	A	419	LEU	0	-0.022	-0.018	34.746	0.003	0.003	0.000	0.000	0.000	0.000
358	A	420	LEU	0	-0.015	-0.008	32.745	0.005	0.005	0.000	0.000	0.000	0.000
359	A	421	ASP	-1	-0.843	-0.919	32.224	0.092	0.092	0.000	0.000	0.000	0.000
360	A	422	LEU	0	-0.014	-0.006	32.369	0.005	0.005	0.000	0.000	0.000	0.000
361	A	423	ASN	0	0.048	0.034	27.781	0.001	0.001	0.000	0.000	0.000	0.000
362	A	424	TYR	0	-0.036	-0.037	27.203	0.006	0.006	0.000	0.000	0.000	0.000
363	A	425	ALA	0	0.027	0.009	27.572	0.010	0.010	0.000	0.000	0.000	0.000
364	A	426	ARG	1	0.857	0.908	24.054	-0.110	-0.110	0.000	0.000	0.000	0.000
365	A	427	GLN	0	-0.023	-0.016	23.723	0.004	0.004	0.000	0.000	0.000	0.000
366	A	428	VAL	0	0.015	0.011	23.057	0.018	0.018	0.000	0.000	0.000	0.000
367	A	429	ASN	0	0.009	0.002	23.742	0.006	0.006	0.000	0.000	0.000	0.000
368	A	430	GLU	-1	-0.827	-0.928	20.444	0.114	0.114	0.000	0.000	0.000	0.000
369	A	431	ILE	0	-0.038	-0.008	18.790	0.020	0.020	0.000	0.000	0.000	0.000
370	A	432	SER	0	0.012	0.009	19.190	0.015	0.015	0.000	0.000	0.000	0.000
371	A	433	LEU	0	0.017	0.024	18.394	-0.008	-0.008	0.000	0.000	0.000	0.000
372	A	434	TYR	0	-0.050	-0.020	11.550	0.026	0.026	0.000	0.000	0.000	0.000
373	A	435	THR	0	0.012	-0.022	15.263	0.033	0.033	0.000	0.000	0.000	0.000
374	A	436	ALA	0	-0.012	0.006	16.526	-0.019	-0.019	0.000	0.000	0.000	0.000
375	A	437	LEU	0	-0.017	-0.019	13.670	-0.042	-0.042	0.000	0.000	0.000	0.000
376	A	438	GLY	0	0.008	0.013	12.715	-0.054	-0.054	0.000	0.000	0.000	0.000
377	A	439	GLY	0	-0.017	-0.011	11.144	0.041	0.041	0.000	0.000	0.000	0.000
378	A	440	GLY	0	-0.030	-0.011	10.330	0.095	0.095	0.000	0.000	0.000	0.000
379	A	441	HIS	0	-0.009	-0.017	11.344	-0.048	-0.048	0.000	0.000	0.000	0.000
380	A	442	HIS	0	0.019	0.019	4.152	-0.428	-0.270	0.000	-0.013	-0.145	0.000

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Interactive mode: IFIE and PIEDA for fragment #1(A:32:TYR)