FMO DATABASE

FMODB ID: 39LLL

Calculation Name: 6XKI-A-MD433-73ns

Preferred Name:

Target Type:

Ligand Name: (3s,6z,8e,11s,15r)-15-amino-3-[(1e,3e,5e)-7-(dimethylamino)-2,5-dimethylhepta-1,3,5-trien-1-yl]-9,11-dimethyl-4,12-dioxa-20-thia-21-azabicyclo[16.2.1]henicosa-1(21),6,8,18-tetraene-5,13-dione

ligand 3-letter code: V6D

PDB ID: 6XKI

Chain ID: A

ChEMBL ID:

UniProt ID:

Base Structure: MD

Registration Date: 2023-09-19

Reference: Hironori Saito, Yuma Handa, Mingming Chen, Tilman Schneider-Poetsch, Yuichi Shichino, Mari Takahashi, Daniel Romo, Minoru Yoshida, Alois F�rstner, Takuhiro Ito, Kaori Fukuzawa, Shintaro Iwasaki Pateamine A mediates RNA sequence-selective translation repression by anchoring eIF4A and DDX3 to GNG motifs, To be published.

DOI:

IFIE MAP

IFIE Diagram

Modeling method

Optimization	AMBER14SB
Restraint	OptAll(Heavy atoms were optimized with constraints.)
Protonation	BaseStructure_original
Complement	MOE:Structure Preparation
Water	No
Procedure	Manual calculation

FMO calculation

FMO method	FMO2-MP2/6-31G(d)
Fragmentation	Manual
Number of fragment	400
LigandCharge	V6D=1
Software	ABINIT-MP - Open Ver. 1 Rev. 23Q2 / 20200603(SMP)

Total energy (hartree)

FMO2-HF: Electronic energy	-7613730.044496
FMO2-HF: Nuclear repulsion	7444675.68828
FMO2-HF: Total energy	-169054.356216
FMO2-MP2: Total energy	-169531.691479

3D Structure

Snapshot

Ligand structure

V6D

Ligand Interaction

Ligand binding energy (frag 399-400 : frag 1-398)

IFIE [kcal/mol]	PIEDA [kcal/mol]				Charge transfer value [e]
IFIE SUMIFIE SUM at MP2 level.	ESElectro static interaction energy.	EXExchange-repulsion energy.	CT+mixCharge transfer and mixing terms energy.	DI(MP2)Dispersion energy.	q(I=>J)Charge transfer value from I to J fragments.
-256.771352	-209.809550	54.899020	-21.378562	-80.482260	0.081073

Interactive mode: IFIE and PIEDA for fragment #399(:389:V6D)

Summations of interaction energy for fragment #399(:389:V6D)

IFIE [kcal/mol]	PIEDA [kcal/mol]				Charge transfer value [e]
IFIE SUMIFIE SUM at MP2 level.	ESElectro static interaction energy.	EXExchange-repulsion energy.	CT+mixCharge transfer and mixing terms energy.	DI(MP2)Dispersion energy.	q(I=>J)Charge transfer value from I to J fragments.
-205.778	-192.694	13.833	-5.318	-21.603	-0.009

Interaction energy analysis for fragmet #399(:389:V6D)

Snapshot

IFIE Diagram

Base fragment(s) of PIEDA/IFIE

Single fragment	Multi fragments
	Fragment list

Charge [e] FCHARGE : 1 / q_Mulliken : 1.006 / q_NPA : 1.008

Distance from base fragment(s) [Å]

Dist

Interaction energy by IFIE and PIEDA
[kcal/mol]

| Total | > | ES | > | EX | >
| CT+mix | > | DI(MP2) | >

Fragment charge [e]

FCHARGE q_Mulliken
q_NPA q(I=>J)

Residue

Res # RES

Sort

Graph Options

X Axis Label
Y Axis Max Y Axis Min
Display ES EX CT+mix DI(MP2)

frag_NumFragment number.	Res #Residue number.	RES3-letter code of amino acid residue, ligand and solvent molecule.	FCHARGEFormal charge [e].	q_MullikenFragment charge evaluated by Mulliken charge [e].	q_NPAFragment charge evaluated by natural population analysis(NPA) charge [e].	DISTDistance from Ligand [Å].	TotalIFIE at MP2 level [kcal/mol].	ESElectro static interaction energy by PIEDA [kcal/mol].	EXExchange-repulsion energy by PIEDA [kcal/mol].	CT+mixCharge transfer and mixing terms energy by PIEDA [kcal/mol].	DI(MP2)Dispersion energy by PIEDA [kcal/mol].	q(I=>J)Charge transfer value from I to J fragmens [e].
82	82	ARG	1	0.882	0.905	2.417	45.112	45.527	1.338	-0.376	-1.377	0.001
108	108	GLY	0	0.015	0.007	4.302	0.372	0.353	-0.001	-0.016	0.035	0.000
109	109	GLY	0	0.023	0.008	5.379	0.882	1.050	-0.001	-0.010	-0.158	0.000
131	131	PRO	0	0.035	0.004	4.740	-0.193	0.146	-0.001	-0.020	-0.318	0.000
132	132	GLY	0	0.029	0.019	2.293	1.007	-0.055	1.025	0.034	0.002	0.001
133	133	ARG	1	0.808	0.846	3.133	32.630	32.250	0.034	0.645	-0.300	-0.001
135	135	PHE	0	0.002	-0.011	5.224	2.541	2.606	-0.001	-0.001	-0.063	0.000
167	167	GLN	0	0.009	0.004	4.636	-2.279	-2.068	-0.001	-0.024	-0.186	0.000
254	254	ARG	1	0.887	0.907	4.542	38.144	38.241	-0.001	-0.001	-0.095	0.000
277	277	ASP	-1	-0.907	-0.935	4.753	-40.349	-40.153	-0.001	-0.005	-0.189	0.000
278	278	MET	0	-0.088	-0.017	4.953	-2.258	-2.209	-0.001	-0.003	-0.045	0.000
279	279	ASP	-1	-0.817	-0.918	5.154	-38.625	-38.533	-0.001	-0.002	-0.089	0.000
390	384	A	-1	-0.467	-0.574	3.112	-31.498	-31.068	0.043	-0.112	-0.362	0.000
391	385	A	0	-0.326	-0.292	2.734	-8.979	-2.216	3.179	-2.089	-7.853	-0.017
392	385	A	-1	-0.448	-0.591	2.163	-46.062	-42.073	6.938	-3.967	-6.960	0.003
393	386	A	0	-0.328	-0.290	2.703	-1.886	0.008	1.080	-0.725	-2.250	0.005
394	386	A	-1	-0.523	-0.614	3.066	-43.278	-43.544	0.206	1.365	-1.304	-0.001
398	388	G	0	0.263	0.227	4.554	-3.149	-3.046	-0.001	-0.011	-0.091	0.000
1	1	GLU	0	-0.128	-0.084	38.067	0.478	0.478	0.000	0.000	0.000	0.000
2	2	ILE	0	0.034	0.019	38.644	-0.184	-0.184	0.000	0.000	0.000	0.000
3	3	VAL	0	0.030	0.021	37.034	0.097	0.097	0.000	0.000	0.000	0.000
4	4	ASP	-1	-0.856	-0.921	39.350	-6.999	-6.999	0.000	0.000	0.000	0.000
5	5	SER	0	0.010	-0.010	39.638	-0.043	-0.043	0.000	0.000	0.000	0.000
6	6	PHE	0	0.028	-0.003	33.128	-0.058	-0.058	0.000	0.000	0.000	0.000
7	7	ASP	-1	-0.889	-0.947	37.359	-7.139	-7.139	0.000	0.000	0.000	0.000
8	8	ASP	-1	-0.872	-0.928	40.170	-6.749	-6.749	0.000	0.000	0.000	0.000
9	9	MET	0	-0.148	-0.068	34.069	-0.107	-0.107	0.000	0.000	0.000	0.000
10	10	ASN	0	-0.083	-0.040	36.782	-0.132	-0.132	0.000	0.000	0.000	0.000
11	11	LEU	0	0.002	0.009	33.084	-0.107	-0.107	0.000	0.000	0.000	0.000
12	12	SER	0	0.011	0.000	34.629	0.273	0.273	0.000	0.000	0.000	0.000
13	13	GLU	-1	-0.923	-0.969	36.612	-7.504	-7.504	0.000	0.000	0.000	0.000
14	14	SER	0	0.062	0.034	35.605	-0.071	-0.071	0.000	0.000	0.000	0.000
15	15	LEU	0	-0.017	-0.011	30.072	-0.185	-0.185	0.000	0.000	0.000	0.000
16	16	LEU	0	-0.014	-0.007	33.573	-0.153	-0.153	0.000	0.000	0.000	0.000
17	17	ARG	1	0.921	0.977	36.154	7.738	7.738	0.000	0.000	0.000	0.000
18	18	GLY	0	0.020	0.012	32.441	-0.013	-0.013	0.000	0.000	0.000	0.000
19	19	ILE	0	-0.027	-0.022	31.332	-0.214	-0.214	0.000	0.000	0.000	0.000
20	20	TYR	0	0.002	-0.009	33.072	-0.063	-0.063	0.000	0.000	0.000	0.000
21	21	ALA	0	-0.028	-0.003	34.017	0.037	0.037	0.000	0.000	0.000	0.000
22	22	TYR	0	-0.050	-0.018	25.839	-0.197	-0.197	0.000	0.000	0.000	0.000
23	23	GLY	0	0.008	0.001	32.002	-0.138	-0.138	0.000	0.000	0.000	0.000
24	24	PHE	0	-0.095	-0.037	29.493	0.109	0.109	0.000	0.000	0.000	0.000
25	25	GLU	-1	-0.872	-0.929	35.445	-7.167	-7.167	0.000	0.000	0.000	0.000
26	26	LYS	1	0.894	0.929	37.958	7.125	7.125	0.000	0.000	0.000	0.000
27	27	PRO	0	-0.009	0.016	34.463	-0.203	-0.203	0.000	0.000	0.000	0.000
28	28	SER	0	0.003	-0.017	31.091	0.222	0.222	0.000	0.000	0.000	0.000
29	29	ALA	0	0.060	0.011	34.279	0.023	0.023	0.000	0.000	0.000	0.000
30	30	ILE	0	-0.038	-0.021	28.580	0.108	0.108	0.000	0.000	0.000	0.000
31	31	GLN	0	0.025	0.018	28.873	0.232	0.232	0.000	0.000	0.000	0.000
32	32	GLN	0	-0.024	-0.012	31.647	0.128	0.128	0.000	0.000	0.000	0.000
33	33	ARG	1	0.894	0.959	32.720	8.651	8.651	0.000	0.000	0.000	0.000
34	34	ALA	0	-0.004	-0.012	28.270	0.016	0.016	0.000	0.000	0.000	0.000
35	35	ILE	0	0.046	0.029	29.165	-0.154	-0.154	0.000	0.000	0.000	0.000
36	36	LEU	0	0.028	0.018	30.562	-0.071	-0.071	0.000	0.000	0.000	0.000
37	37	PRO	0	-0.054	-0.024	30.499	0.032	0.032	0.000	0.000	0.000	0.000
38	38	CYS	0	0.002	0.014	25.369	-0.182	-0.182	0.000	0.000	0.000	0.000
39	39	ILE	0	0.081	0.042	28.156	-0.105	-0.105	0.000	0.000	0.000	0.000
40	40	LYS	1	0.876	0.937	30.214	7.848	7.848	0.000	0.000	0.000	0.000
41	41	GLY	0	0.009	0.016	27.850	0.141	0.141	0.000	0.000	0.000	0.000
42	42	TYR	0	-0.062	-0.029	27.578	-0.035	-0.035	0.000	0.000	0.000	0.000
43	43	ASP	-1	-0.815	-0.899	24.296	-11.029	-11.029	0.000	0.000	0.000	0.000
44	44	VAL	0	-0.064	-0.046	24.278	0.368	0.368	0.000	0.000	0.000	0.000
45	45	ILE	0	-0.005	0.002	23.149	-0.473	-0.473	0.000	0.000	0.000	0.000
46	46	ALA	0	-0.017	-0.021	24.322	0.485	0.485	0.000	0.000	0.000	0.000
47	47	GLN	0	0.018	0.019	25.030	-0.154	-0.154	0.000	0.000	0.000	0.000
48	48	ALA	0	-0.020	-0.029	26.413	0.472	0.472	0.000	0.000	0.000	0.000
49	49	GLN	0	0.047	0.024	26.517	-0.691	-0.691	0.000	0.000	0.000	0.000
50	50	SER	0	0.017	-0.006	22.820	0.092	0.092	0.000	0.000	0.000	0.000
51	51	GLY	0	0.015	0.014	25.329	-0.109	-0.109	0.000	0.000	0.000	0.000
52	52	THR	0	-0.015	-0.001	27.915	0.090	0.090	0.000	0.000	0.000	0.000
53	53	GLY	0	0.066	0.037	27.887	0.183	0.183	0.000	0.000	0.000	0.000
54	54	LYS	1	0.826	0.911	20.443	13.192	13.192	0.000	0.000	0.000	0.000
55	55	THR	0	0.034	0.009	21.024	-0.308	-0.308	0.000	0.000	0.000	0.000
56	56	ALA	0	0.046	0.018	23.108	-0.055	-0.055	0.000	0.000	0.000	0.000
57	57	THR	0	-0.013	0.002	25.265	0.284	0.284	0.000	0.000	0.000	0.000
58	58	PHE	0	0.059	0.038	19.100	0.201	0.201	0.000	0.000	0.000	0.000
59	59	ALA	0	0.014	0.008	23.173	0.142	0.142	0.000	0.000	0.000	0.000
60	60	ILE	0	0.018	0.008	24.316	0.152	0.152	0.000	0.000	0.000	0.000
61	61	SER	0	-0.006	-0.033	26.069	0.348	0.348	0.000	0.000	0.000	0.000
62	62	ILE	0	-0.008	0.004	20.961	0.080	0.080	0.000	0.000	0.000	0.000
63	63	LEU	0	-0.003	-0.004	25.304	0.151	0.151	0.000	0.000	0.000	0.000
64	64	GLN	0	0.032	0.018	27.515	0.181	0.181	0.000	0.000	0.000	0.000
65	65	GLN	0	-0.092	-0.059	26.447	0.295	0.295	0.000	0.000	0.000	0.000
66	66	ILE	0	-0.089	-0.028	23.412	-0.062	-0.062	0.000	0.000	0.000	0.000
67	67	GLU	-1	-0.872	-0.929	27.572	-8.478	-8.478	0.000	0.000	0.000	0.000
68	68	LEU	0	0.006	-0.009	28.014	-0.350	-0.350	0.000	0.000	0.000	0.000
69	69	ASP	-1	-0.897	-0.941	29.390	-8.651	-8.651	0.000	0.000	0.000	0.000
70	70	LEU	0	-0.092	-0.037	25.656	-0.006	-0.006	0.000	0.000	0.000	0.000
71	71	LYS	1	0.935	0.960	26.839	9.334	9.334	0.000	0.000	0.000	0.000
72	72	ALA	0	0.002	-0.011	22.573	-0.297	-0.297	0.000	0.000	0.000	0.000
73	73	THR	0	-0.021	-0.012	17.364	0.085	0.085	0.000	0.000	0.000	0.000
74	74	GLN	0	-0.046	-0.027	20.660	0.159	0.159	0.000	0.000	0.000	0.000
75	75	ALA	0	-0.019	-0.006	19.697	0.107	0.107	0.000	0.000	0.000	0.000
76	76	LEU	0	-0.010	-0.001	11.894	-0.390	-0.390	0.000	0.000	0.000	0.000
77	77	VAL	0	-0.024	-0.012	15.113	0.319	0.319	0.000	0.000	0.000	0.000
78	78	LEU	0	-0.017	-0.009	9.074	-1.011	-1.011	0.000	0.000	0.000	0.000
79	79	ALA	0	0.036	-0.004	11.151	1.327	1.327	0.000	0.000	0.000	0.000
80	80	PRO	0	0.024	0.016	10.076	-1.372	-1.372	0.000	0.000	0.000	0.000
81	81	THR	0	0.034	0.037	8.138	-1.554	-1.554	0.000	0.000	0.000	0.000
83	83	GLU	-1	-0.784	-0.853	9.359	-22.757	-22.757	0.000	0.000	0.000	0.000
84	84	LEU	0	-0.026	-0.010	12.163	1.448	1.448	0.000	0.000	0.000	0.000
85	85	ALA	0	0.013	0.009	11.513	1.094	1.094	0.000	0.000	0.000	0.000
86	86	GLN	0	-0.027	-0.039	12.197	1.605	1.605	0.000	0.000	0.000	0.000
87	87	GLN	0	-0.034	0.003	15.253	0.724	0.724	0.000	0.000	0.000	0.000
88	88	ILE	0	0.035	0.007	15.844	0.829	0.829	0.000	0.000	0.000	0.000
89	89	GLN	0	0.009	0.005	17.144	0.767	0.767	0.000	0.000	0.000	0.000
90	90	LYS	1	0.970	0.978	18.653	15.318	15.318	0.000	0.000	0.000	0.000
91	91	VAL	0	-0.033	0.000	21.566	0.547	0.547	0.000	0.000	0.000	0.000
92	92	VAL	0	-0.001	-0.010	20.507	0.505	0.505	0.000	0.000	0.000	0.000
93	93	MET	0	-0.011	-0.003	22.325	0.309	0.309	0.000	0.000	0.000	0.000
94	94	ALA	0	-0.004	0.021	24.872	0.344	0.344	0.000	0.000	0.000	0.000
95	95	LEU	0	-0.042	-0.029	25.689	0.368	0.368	0.000	0.000	0.000	0.000
96	96	GLY	0	0.007	-0.011	27.143	0.343	0.343	0.000	0.000	0.000	0.000
97	97	ASP	-1	-0.953	-0.954	28.371	-9.619	-9.619	0.000	0.000	0.000	0.000
98	98	TYR	0	-0.023	-0.034	30.374	0.240	0.240	0.000	0.000	0.000	0.000
99	99	MET	0	-0.086	-0.019	29.062	0.088	0.088	0.000	0.000	0.000	0.000
100	100	GLY	0	0.057	0.018	30.542	0.178	0.178	0.000	0.000	0.000	0.000
101	101	ALA	0	-0.033	-0.022	25.413	-0.180	-0.180	0.000	0.000	0.000	0.000
102	102	SER	0	-0.032	-0.035	23.676	-0.233	-0.233	0.000	0.000	0.000	0.000
103	103	CYS	0	-0.064	-0.037	18.998	-0.388	-0.388	0.000	0.000	0.000	0.000
104	104	HIS	0	-0.019	-0.023	13.433	0.804	0.804	0.000	0.000	0.000	0.000
105	105	ALA	0	0.005	0.001	13.423	-0.033	-0.033	0.000	0.000	0.000	0.000
106	106	CYS	0	-0.086	-0.033	10.387	-0.810	-0.810	0.000	0.000	0.000	0.000
107	107	ILE	0	0.006	0.002	7.889	-0.890	-0.890	0.000	0.000	0.000	0.000
110	110	THR	0	0.025	0.032	6.649	2.118	2.118	0.000	0.000	0.000	0.000
111	111	ASN	0	0.031	0.011	9.898	-0.435	-0.435	0.000	0.000	0.000	0.000
112	112	VAL	0	0.076	0.033	11.000	1.269	1.269	0.000	0.000	0.000	0.000
113	113	ARG	1	0.951	0.968	12.655	18.326	18.326	0.000	0.000	0.000	0.000
114	114	ALA	0	0.026	0.021	15.666	1.020	1.020	0.000	0.000	0.000	0.000
115	115	GLU	-1	-0.738	-0.847	11.601	-21.425	-21.425	0.000	0.000	0.000	0.000
116	116	VAL	0	-0.024	-0.022	15.139	0.806	0.806	0.000	0.000	0.000	0.000
117	117	GLN	0	-0.021	-0.006	17.394	0.452	0.452	0.000	0.000	0.000	0.000
118	118	LYS	1	0.901	0.959	17.285	16.173	16.173	0.000	0.000	0.000	0.000
119	119	LEU	0	0.001	-0.019	14.648	0.631	0.631	0.000	0.000	0.000	0.000
120	120	GLN	0	-0.048	-0.023	19.212	0.622	0.622	0.000	0.000	0.000	0.000
121	121	MET	0	-0.053	-0.025	21.894	0.422	0.422	0.000	0.000	0.000	0.000
122	122	GLU	-1	-0.892	-0.917	21.700	-11.525	-11.525	0.000	0.000	0.000	0.000
123	123	ALA	0	-0.038	-0.011	21.104	0.233	0.233	0.000	0.000	0.000	0.000
124	124	PRO	0	0.009	0.025	18.893	0.245	0.245	0.000	0.000	0.000	0.000
125	125	HIS	0	0.105	0.063	20.693	-0.692	-0.692	0.000	0.000	0.000	0.000
126	126	ILE	0	-0.007	-0.003	18.503	-0.087	-0.087	0.000	0.000	0.000	0.000
127	127	ILE	0	-0.007	-0.014	13.302	-0.332	-0.332	0.000	0.000	0.000	0.000
128	128	VAL	0	0.029	0.018	13.665	0.120	0.120	0.000	0.000	0.000	0.000
129	129	GLY	0	0.006	-0.012	10.148	-0.329	-0.329	0.000	0.000	0.000	0.000
130	130	THR	0	0.006	0.000	5.794	1.271	1.271	0.000	0.000	0.000	0.000
134	134	VAL	0	0.067	0.025	6.404	2.583	2.583	0.000	0.000	0.000	0.000
136	136	ASP	-1	-0.785	-0.844	6.680	-24.260	-24.260	0.000	0.000	0.000	0.000
137	137	MET	0	-0.023	-0.014	8.146	2.681	2.681	0.000	0.000	0.000	0.000
138	138	LEU	0	0.007	0.016	9.956	1.749	1.749	0.000	0.000	0.000	0.000
139	139	ASN	0	-0.076	-0.021	10.382	2.274	2.274	0.000	0.000	0.000	0.000
140	140	ARG	1	0.761	0.840	10.433	24.009	24.009	0.000	0.000	0.000	0.000
141	141	ARG	1	0.842	0.921	14.168	16.334	16.334	0.000	0.000	0.000	0.000
142	142	TYR	0	0.021	0.015	15.177	0.996	0.996	0.000	0.000	0.000	0.000
143	143	LEU	0	0.027	0.047	11.867	0.395	0.395	0.000	0.000	0.000	0.000
144	144	SER	0	0.016	-0.020	15.507	-0.169	-0.169	0.000	0.000	0.000	0.000
145	145	PRO	0	0.038	0.015	15.803	0.460	0.460	0.000	0.000	0.000	0.000
146	146	LYS	1	0.881	0.940	18.345	11.003	11.003	0.000	0.000	0.000	0.000
147	147	TYR	0	-0.012	-0.007	20.809	0.438	0.438	0.000	0.000	0.000	0.000
148	148	ILE	0	-0.001	0.018	15.513	0.075	0.075	0.000	0.000	0.000	0.000
149	149	LYS	1	0.970	0.990	19.810	10.170	10.170	0.000	0.000	0.000	0.000
150	150	MET	0	-0.016	0.004	21.011	0.204	0.204	0.000	0.000	0.000	0.000
151	151	PHE	0	0.021	0.005	12.099	-0.523	-0.523	0.000	0.000	0.000	0.000
152	152	VAL	0	-0.004	-0.008	16.377	0.540	0.540	0.000	0.000	0.000	0.000
153	153	LEU	0	0.012	0.013	12.801	-0.952	-0.952	0.000	0.000	0.000	0.000
154	154	ASP	-1	-0.806	-0.901	15.518	-13.210	-13.210	0.000	0.000	0.000	0.000
155	155	GLU	-1	-0.854	-0.935	15.411	-15.190	-15.190	0.000	0.000	0.000	0.000
156	156	ALA	0	0.012	-0.002	16.042	-0.518	-0.518	0.000	0.000	0.000	0.000
157	157	ASP	-1	-0.776	-0.831	16.250	-14.415	-14.415	0.000	0.000	0.000	0.000
158	158	GLU	-1	-0.909	-0.954	12.602	-18.875	-18.875	0.000	0.000	0.000	0.000
159	159	MET	0	-0.057	-0.018	8.752	-0.956	-0.956	0.000	0.000	0.000	0.000
160	160	LEU	0	-0.032	-0.027	12.057	-0.610	-0.610	0.000	0.000	0.000	0.000
161	161	SER	0	0.038	0.032	14.048	0.862	0.862	0.000	0.000	0.000	0.000
162	162	ARG	1	0.781	0.857	12.699	18.987	18.987	0.000	0.000	0.000	0.000
163	163	GLY	0	0.071	0.044	9.952	-0.561	-0.561	0.000	0.000	0.000	0.000
164	164	PHE	0	-0.041	-0.021	5.852	-2.541	-2.541	0.000	0.000	0.000	0.000
165	165	LYS	1	0.958	0.994	9.108	16.025	16.025	0.000	0.000	0.000	0.000
166	166	ASP	-1	-0.906	-0.960	9.341	-17.991	-17.991	0.000	0.000	0.000	0.000
168	168	ILE	0	0.006	-0.002	6.974	0.687	0.687	0.000	0.000	0.000	0.000
169	169	TYR	0	0.021	0.000	10.166	1.016	1.016	0.000	0.000	0.000	0.000
170	170	ASP	-1	-0.882	-0.929	8.553	-18.826	-18.826	0.000	0.000	0.000	0.000
171	171	ILE	0	-0.054	-0.026	6.978	0.660	0.660	0.000	0.000	0.000	0.000
172	172	PHE	0	-0.024	-0.025	10.372	1.074	1.074	0.000	0.000	0.000	0.000
173	173	GLN	0	-0.034	-0.028	13.270	1.285	1.285	0.000	0.000	0.000	0.000
174	174	LYS	1	0.898	0.961	11.836	17.449	17.449	0.000	0.000	0.000	0.000
175	175	LEU	0	-0.010	0.004	14.337	0.526	0.526	0.000	0.000	0.000	0.000
176	176	ASN	0	0.037	0.027	16.752	0.535	0.535	0.000	0.000	0.000	0.000
177	177	SER	0	0.048	0.024	20.600	-0.132	-0.132	0.000	0.000	0.000	0.000
178	178	ASN	0	-0.100	-0.054	22.332	0.421	0.421	0.000	0.000	0.000	0.000
179	179	THR	0	-0.072	-0.040	18.487	0.109	0.109	0.000	0.000	0.000	0.000
180	180	GLN	0	-0.007	-0.002	21.692	-0.075	-0.075	0.000	0.000	0.000	0.000
181	181	VAL	0	-0.013	-0.011	18.322	-0.603	-0.603	0.000	0.000	0.000	0.000
182	182	VAL	0	-0.020	-0.018	20.190	0.525	0.525	0.000	0.000	0.000	0.000
183	183	LEU	0	-0.014	-0.004	17.953	-0.634	-0.634	0.000	0.000	0.000	0.000
184	184	LEU	0	-0.002	-0.004	19.814	0.662	0.662	0.000	0.000	0.000	0.000
185	185	SER	0	-0.024	-0.032	19.829	-0.615	-0.615	0.000	0.000	0.000	0.000
186	186	ALA	0	0.036	0.029	21.769	0.505	0.505	0.000	0.000	0.000	0.000
187	187	THR	0	-0.030	-0.028	21.056	0.446	0.446	0.000	0.000	0.000	0.000
188	188	MET	0	-0.012	-0.015	20.737	-0.434	-0.434	0.000	0.000	0.000	0.000
189	189	PRO	0	0.067	0.042	21.679	0.508	0.508	0.000	0.000	0.000	0.000
190	190	SER	0	-0.023	-0.024	23.616	-0.217	-0.217	0.000	0.000	0.000	0.000
191	191	ASP	-1	-0.850	-0.929	21.842	-11.498	-11.498	0.000	0.000	0.000	0.000
192	192	VAL	0	-0.009	0.009	18.627	-0.376	-0.376	0.000	0.000	0.000	0.000
193	193	LEU	0	-0.066	-0.049	20.618	0.092	0.092	0.000	0.000	0.000	0.000
194	194	GLU	-1	-1.010	-0.992	21.570	-11.739	-11.739	0.000	0.000	0.000	0.000
195	195	VAL	0	0.044	0.030	16.392	-0.071	-0.071	0.000	0.000	0.000	0.000
196	196	THR	0	0.002	-0.014	19.314	-0.067	-0.067	0.000	0.000	0.000	0.000
197	197	LYS	1	0.935	0.966	20.879	10.217	10.217	0.000	0.000	0.000	0.000
198	198	LYS	1	0.896	0.970	15.095	15.237	15.237	0.000	0.000	0.000	0.000
199	199	PHE	0	-0.029	-0.014	13.810	-0.282	-0.282	0.000	0.000	0.000	0.000
200	200	MET	0	-0.021	-0.002	19.535	0.264	0.264	0.000	0.000	0.000	0.000
201	201	ARG	1	0.925	0.951	23.295	9.603	9.603	0.000	0.000	0.000	0.000
202	202	ASP	-1	-0.939	-0.952	26.917	-8.554	-8.554	0.000	0.000	0.000	0.000
203	203	PRO	0	0.002	0.009	25.681	0.123	0.123	0.000	0.000	0.000	0.000
204	204	ILE	0	0.013	0.011	28.117	0.294	0.294	0.000	0.000	0.000	0.000
205	205	ARG	1	0.936	0.961	27.672	9.217	9.217	0.000	0.000	0.000	0.000
206	206	ILE	0	-0.026	-0.012	28.614	0.322	0.322	0.000	0.000	0.000	0.000
207	207	LEU	0	-0.005	-0.012	27.551	-0.319	-0.319	0.000	0.000	0.000	0.000
208	208	VAL	0	-0.008	-0.006	29.453	0.283	0.283	0.000	0.000	0.000	0.000
209	209	LYS	1	0.946	0.975	30.452	7.721	7.721	0.000	0.000	0.000	0.000
210	210	LYS	1	0.834	0.902	30.258	8.825	8.825	0.000	0.000	0.000	0.000
211	211	GLU	-1	-0.808	-0.904	31.009	-8.705	-8.705	0.000	0.000	0.000	0.000
212	212	GLU	-1	-0.945	-0.965	33.104	-8.028	-8.028	0.000	0.000	0.000	0.000
213	213	LEU	0	-0.078	-0.040	26.513	-0.073	-0.073	0.000	0.000	0.000	0.000
214	214	THR	0	0.016	0.018	29.245	-0.289	-0.289	0.000	0.000	0.000	0.000
215	215	LEU	0	-0.046	-0.020	26.884	0.101	0.101	0.000	0.000	0.000	0.000
216	216	GLU	-1	-0.912	-0.949	31.413	-7.801	-7.801	0.000	0.000	0.000	0.000
217	217	GLY	0	-0.051	-0.029	33.277	0.112	0.112	0.000	0.000	0.000	0.000
218	218	ILE	0	-0.064	-0.034	27.962	0.076	0.076	0.000	0.000	0.000	0.000
219	219	ARG	1	0.813	0.903	31.346	8.506	8.506	0.000	0.000	0.000	0.000
220	220	GLN	0	-0.014	-0.001	30.653	-0.507	-0.507	0.000	0.000	0.000	0.000
221	221	PHE	0	0.062	0.020	31.585	0.232	0.232	0.000	0.000	0.000	0.000
222	222	TYR	0	-0.061	-0.024	31.364	-0.451	-0.451	0.000	0.000	0.000	0.000
223	223	ILE	0	0.054	0.019	31.820	0.278	0.278	0.000	0.000	0.000	0.000
224	224	ASN	0	0.007	-0.005	32.708	-0.449	-0.449	0.000	0.000	0.000	0.000
225	225	VAL	0	0.007	0.006	30.915	0.144	0.144	0.000	0.000	0.000	0.000
226	226	GLU	-1	-0.963	-0.965	34.232	-7.895	-7.895	0.000	0.000	0.000	0.000
227	227	ARG	1	0.873	0.908	32.040	8.594	8.594	0.000	0.000	0.000	0.000
228	228	GLU	-1	-0.720	-0.853	24.866	-11.925	-11.925	0.000	0.000	0.000	0.000
229	229	GLU	-1	-0.892	-0.949	28.799	-9.738	-9.738	0.000	0.000	0.000	0.000
230	230	TRP	0	0.006	0.012	30.378	-0.018	-0.018	0.000	0.000	0.000	0.000
231	231	LYS	1	0.822	0.916	24.332	11.988	11.988	0.000	0.000	0.000	0.000
232	232	LEU	0	0.002	-0.003	25.696	-0.056	-0.056	0.000	0.000	0.000	0.000
233	233	ASP	-1	-0.833	-0.914	28.374	-9.285	-9.285	0.000	0.000	0.000	0.000
234	234	THR	0	-0.009	-0.003	31.875	0.252	0.252	0.000	0.000	0.000	0.000
235	235	LEU	0	-0.032	-0.020	25.671	0.036	0.036	0.000	0.000	0.000	0.000
236	236	CYS	0	-0.101	-0.063	29.579	-0.047	-0.047	0.000	0.000	0.000	0.000
237	237	ASP	-1	-0.871	-0.925	31.256	-8.405	-8.405	0.000	0.000	0.000	0.000
238	238	LEU	0	-0.038	-0.006	30.271	0.124	0.124	0.000	0.000	0.000	0.000
239	239	TYR	0	-0.016	-0.032	27.279	0.090	0.090	0.000	0.000	0.000	0.000
240	240	GLU	-1	-0.909	-0.947	31.797	-7.964	-7.964	0.000	0.000	0.000	0.000
241	241	THR	0	-0.014	-0.007	32.851	0.053	0.053	0.000	0.000	0.000	0.000
242	242	LEU	0	-0.003	0.005	27.429	-0.009	-0.009	0.000	0.000	0.000	0.000
243	243	THR	0	-0.071	-0.047	31.781	-0.036	-0.036	0.000	0.000	0.000	0.000
244	244	ILE	0	-0.010	0.001	34.589	0.061	0.061	0.000	0.000	0.000	0.000
245	245	THR	0	-0.093	-0.057	30.200	-0.123	-0.123	0.000	0.000	0.000	0.000
246	246	GLN	0	-0.007	-0.003	23.397	0.359	0.359	0.000	0.000	0.000	0.000
247	247	ALA	0	0.011	0.003	25.451	0.048	0.048	0.000	0.000	0.000	0.000
248	248	VAL	0	-0.015	-0.004	19.235	-0.347	-0.347	0.000	0.000	0.000	0.000
249	249	ILE	0	0.005	-0.002	20.975	0.491	0.491	0.000	0.000	0.000	0.000
250	250	PHE	0	0.030	0.007	16.923	-0.708	-0.708	0.000	0.000	0.000	0.000
251	251	ILE	0	-0.036	-0.020	16.772	0.697	0.697	0.000	0.000	0.000	0.000
252	252	ASN	0	0.022	-0.002	16.920	-0.793	-0.793	0.000	0.000	0.000	0.000
253	253	THR	0	-0.029	-0.009	14.134	-0.457	-0.457	0.000	0.000	0.000	0.000
255	255	ARG	1	0.927	0.963	12.284	19.744	19.744	0.000	0.000	0.000	0.000
256	256	LYS	1	0.811	0.880	14.584	14.120	14.120	0.000	0.000	0.000	0.000
257	257	VAL	0	0.038	0.027	13.887	0.811	0.811	0.000	0.000	0.000	0.000
258	258	ASP	-1	-0.862	-0.919	13.160	-19.188	-19.188	0.000	0.000	0.000	0.000
259	259	TRP	0	-0.006	0.002	15.743	0.844	0.844	0.000	0.000	0.000	0.000
260	260	LEU	0	-0.004	-0.011	19.225	0.626	0.626	0.000	0.000	0.000	0.000
261	261	THR	0	0.009	-0.021	17.760	0.667	0.667	0.000	0.000	0.000	0.000
262	262	GLU	-1	-0.917	-0.944	19.730	-13.094	-13.094	0.000	0.000	0.000	0.000
263	263	LYS	1	0.838	0.919	21.362	12.607	12.607	0.000	0.000	0.000	0.000
264	264	MET	0	0.020	0.006	23.790	0.338	0.338	0.000	0.000	0.000	0.000
265	265	HIS	0	-0.007	0.005	22.695	0.464	0.464	0.000	0.000	0.000	0.000
266	266	ALA	0	-0.020	-0.014	24.805	0.350	0.350	0.000	0.000	0.000	0.000
267	267	ARG	1	0.785	0.883	26.974	10.185	10.185	0.000	0.000	0.000	0.000
268	268	ASP	-1	-0.876	-0.931	29.086	-9.084	-9.084	0.000	0.000	0.000	0.000
269	269	PHE	0	-0.046	-0.008	27.467	0.068	0.068	0.000	0.000	0.000	0.000
270	270	THR	0	-0.011	-0.006	25.782	-0.339	-0.339	0.000	0.000	0.000	0.000
271	271	VAL	0	-0.016	-0.005	21.410	-0.023	-0.023	0.000	0.000	0.000	0.000
272	272	SER	0	0.005	0.001	19.004	-0.374	-0.374	0.000	0.000	0.000	0.000
273	273	ALA	0	0.024	0.015	16.018	0.224	0.224	0.000	0.000	0.000	0.000
274	274	MET	0	-0.032	-0.011	11.946	-0.181	-0.181	0.000	0.000	0.000	0.000
275	275	HIS	0	-0.006	-0.012	9.766	-0.819	-0.819	0.000	0.000	0.000	0.000
276	276	GLY	0	0.023	-0.005	6.688	-1.084	-1.084	0.000	0.000	0.000	0.000
280	280	GLN	0	-0.023	-0.025	6.255	0.312	0.312	0.000	0.000	0.000	0.000
281	281	LYS	1	0.798	0.878	8.088	25.986	25.986	0.000	0.000	0.000	0.000
282	282	GLU	-1	-0.831	-0.900	9.849	-20.468	-20.468	0.000	0.000	0.000	0.000
283	283	ARG	1	0.792	0.841	5.486	33.689	33.689	0.000	0.000	0.000	0.000
284	284	ASP	-1	-0.797	-0.876	11.262	-16.365	-16.365	0.000	0.000	0.000	0.000
285	285	VAL	0	-0.015	-0.009	13.812	1.245	1.245	0.000	0.000	0.000	0.000
286	286	ILE	0	0.021	0.024	13.180	1.113	1.113	0.000	0.000	0.000	0.000
287	287	MET	0	0.004	0.015	15.098	1.328	1.328	0.000	0.000	0.000	0.000
288	288	ARG	1	0.774	0.848	17.066	16.743	16.743	0.000	0.000	0.000	0.000
289	289	GLU	-1	-0.813	-0.859	19.535	-11.634	-11.634	0.000	0.000	0.000	0.000
290	290	PHE	0	0.005	0.013	19.961	0.595	0.595	0.000	0.000	0.000	0.000
291	291	ARG	1	0.853	0.893	17.459	15.303	15.303	0.000	0.000	0.000	0.000
292	292	SER	0	-0.051	-0.031	22.383	0.564	0.564	0.000	0.000	0.000	0.000
293	293	GLY	0	-0.073	-0.031	25.133	0.464	0.464	0.000	0.000	0.000	0.000
294	294	SER	0	-0.084	-0.049	25.282	0.380	0.380	0.000	0.000	0.000	0.000
295	295	SER	0	0.014	0.009	21.161	0.237	0.237	0.000	0.000	0.000	0.000
296	296	ARG	1	0.911	0.955	24.270	9.772	9.772	0.000	0.000	0.000	0.000
297	297	VAL	0	0.012	-0.008	23.493	0.151	0.151	0.000	0.000	0.000	0.000
298	298	LEU	0	-0.020	-0.003	16.723	-0.326	-0.326	0.000	0.000	0.000	0.000
299	299	ILE	0	0.008	0.007	17.595	0.128	0.128	0.000	0.000	0.000	0.000
300	300	THR	0	-0.034	-0.045	14.617	-1.232	-1.232	0.000	0.000	0.000	0.000
301	301	THR	0	0.025	-0.010	11.059	1.223	1.223	0.000	0.000	0.000	0.000
302	302	ASP	-1	-0.794	-0.876	13.002	-16.485	-16.485	0.000	0.000	0.000	0.000
303	303	LEU	0	-0.005	0.013	8.119	-0.191	-0.191	0.000	0.000	0.000	0.000
304	304	LEU	0	-0.026	-0.026	11.100	0.224	0.224	0.000	0.000	0.000	0.000
305	305	ALA	0	0.019	0.019	14.200	1.098	1.098	0.000	0.000	0.000	0.000
306	306	ARG	1	0.839	0.894	14.124	16.043	16.043	0.000	0.000	0.000	0.000
307	307	GLY	0	0.040	0.023	15.559	-0.583	-0.583	0.000	0.000	0.000	0.000
308	308	ILE	0	-0.034	-0.016	14.116	0.511	0.511	0.000	0.000	0.000	0.000
309	309	ASP	-1	-0.832	-0.895	17.916	-11.803	-11.803	0.000	0.000	0.000	0.000
310	310	VAL	0	-0.009	-0.004	19.996	-0.177	-0.177	0.000	0.000	0.000	0.000
311	311	GLN	0	0.019	-0.001	22.679	0.432	0.432	0.000	0.000	0.000	0.000
312	312	GLN	0	0.007	-0.006	25.721	0.205	0.205	0.000	0.000	0.000	0.000
313	313	VAL	0	-0.016	0.012	23.060	0.269	0.269	0.000	0.000	0.000	0.000
314	314	SER	0	-0.036	-0.019	26.500	0.105	0.105	0.000	0.000	0.000	0.000
315	315	LEU	0	0.072	0.036	28.032	-0.005	-0.005	0.000	0.000	0.000	0.000
316	316	VAL	0	-0.024	-0.010	23.101	-0.409	-0.409	0.000	0.000	0.000	0.000
317	317	ILE	0	0.026	0.009	24.291	0.396	0.396	0.000	0.000	0.000	0.000
318	318	ASN	0	0.009	-0.002	22.390	-1.179	-1.179	0.000	0.000	0.000	0.000
319	319	TYR	0	0.060	0.028	22.716	0.543	0.543	0.000	0.000	0.000	0.000
320	320	ASP	-1	-0.782	-0.875	20.417	-13.525	-13.525	0.000	0.000	0.000	0.000
321	321	LEU	0	0.048	0.026	22.272	-0.321	-0.321	0.000	0.000	0.000	0.000
322	322	PRO	0	-0.028	0.007	20.143	-0.277	-0.277	0.000	0.000	0.000	0.000
323	323	THR	0	0.044	0.006	19.900	0.397	0.397	0.000	0.000	0.000	0.000
324	324	ASN	0	0.014	0.020	19.246	0.179	0.179	0.000	0.000	0.000	0.000
325	325	ARG	1	0.918	0.925	21.264	10.454	10.454	0.000	0.000	0.000	0.000
326	326	GLU	-1	-0.908	-0.942	20.855	-11.770	-11.770	0.000	0.000	0.000	0.000
327	327	ASN	0	-0.035	-0.043	17.093	-0.050	-0.050	0.000	0.000	0.000	0.000
328	328	TYR	0	-0.038	-0.022	19.771	-0.080	-0.080	0.000	0.000	0.000	0.000
329	329	ILE	0	0.003	-0.002	23.116	0.090	0.090	0.000	0.000	0.000	0.000
330	330	HIS	0	-0.046	-0.031	19.314	0.111	0.111	0.000	0.000	0.000	0.000
331	331	ARG	1	0.793	0.867	17.369	15.073	15.073	0.000	0.000	0.000	0.000
332	332	ILE	0	0.011	0.005	20.971	0.099	0.099	0.000	0.000	0.000	0.000
333	333	GLY	0	0.006	0.012	23.720	0.358	0.358	0.000	0.000	0.000	0.000
334	334	ARG	1	0.779	0.881	18.354	13.567	13.567	0.000	0.000	0.000	0.000
335	335	GLY	0	0.042	0.033	22.344	-0.013	-0.013	0.000	0.000	0.000	0.000
336	336	GLY	0	-0.016	-0.015	25.837	0.060	0.060	0.000	0.000	0.000	0.000
337	337	ARG	1	0.774	0.905	23.225	11.461	11.461	0.000	0.000	0.000	0.000
338	338	PHE	0	-0.009	-0.024	27.325	0.273	0.273	0.000	0.000	0.000	0.000
339	339	GLY	0	0.017	0.016	29.780	0.266	0.266	0.000	0.000	0.000	0.000
340	340	ARG	1	0.863	0.946	29.826	9.938	9.938	0.000	0.000	0.000	0.000
341	341	LYS	1	0.977	0.979	31.784	7.561	7.561	0.000	0.000	0.000	0.000
342	342	GLY	0	0.083	0.049	30.255	0.058	0.058	0.000	0.000	0.000	0.000
343	343	VAL	0	-0.015	0.008	30.069	0.244	0.244	0.000	0.000	0.000	0.000
344	344	ALA	0	0.017	0.001	27.523	-0.395	-0.395	0.000	0.000	0.000	0.000
345	345	ILE	0	0.049	0.037	28.515	0.237	0.237	0.000	0.000	0.000	0.000
346	346	ASN	0	-0.032	-0.028	26.951	-0.880	-0.880	0.000	0.000	0.000	0.000
347	347	MET	0	-0.010	0.001	27.563	0.255	0.255	0.000	0.000	0.000	0.000
348	348	VAL	0	-0.049	-0.016	27.999	-0.305	-0.305	0.000	0.000	0.000	0.000
349	349	THR	0	-0.023	-0.026	28.647	0.349	0.349	0.000	0.000	0.000	0.000
350	350	GLU	-1	-0.869	-0.958	31.295	-8.324	-8.324	0.000	0.000	0.000	0.000
351	351	GLU	-1	-0.922	-0.953	29.893	-9.454	-9.454	0.000	0.000	0.000	0.000
352	352	ASP	-1	-0.839	-0.905	27.305	-11.069	-11.069	0.000	0.000	0.000	0.000
353	353	LYS	1	0.871	0.940	29.575	8.366	8.366	0.000	0.000	0.000	0.000
354	354	ARG	1	0.959	0.980	31.309	9.452	9.452	0.000	0.000	0.000	0.000
355	355	THR	0	0.002	-0.002	25.414	-0.044	-0.044	0.000	0.000	0.000	0.000
356	356	LEU	0	0.035	0.023	28.824	-0.100	-0.100	0.000	0.000	0.000	0.000
357	357	ARG	1	0.899	0.957	30.348	8.201	8.201	0.000	0.000	0.000	0.000
358	358	ASP	-1	-0.869	-0.917	28.622	-9.992	-9.992	0.000	0.000	0.000	0.000
359	359	ILE	0	0.024	0.020	25.584	0.034	0.034	0.000	0.000	0.000	0.000
360	360	GLU	-1	-0.820	-0.903	29.717	-8.269	-8.269	0.000	0.000	0.000	0.000
361	361	THR	0	-0.097	-0.065	33.098	0.242	0.242	0.000	0.000	0.000	0.000
362	362	PHE	0	-0.025	-0.003	28.089	0.154	0.154	0.000	0.000	0.000	0.000
363	363	TYR	0	-0.014	-0.033	25.447	0.099	0.099	0.000	0.000	0.000	0.000
364	364	ASN	0	-0.088	-0.030	32.373	0.116	0.116	0.000	0.000	0.000	0.000
365	365	THR	0	0.009	-0.006	34.149	0.259	0.259	0.000	0.000	0.000	0.000
366	366	SER	0	-0.008	-0.005	34.668	-0.174	-0.174	0.000	0.000	0.000	0.000
367	367	ILE	0	-0.050	-0.029	30.455	-0.127	-0.127	0.000	0.000	0.000	0.000
368	368	GLU	-1	-0.902	-0.942	34.541	-7.521	-7.521	0.000	0.000	0.000	0.000
369	369	GLU	-1	-0.943	-0.972	35.824	-7.758	-7.758	0.000	0.000	0.000	0.000
370	370	MET	0	-0.047	-0.020	34.498	-0.038	-0.038	0.000	0.000	0.000	0.000
371	371	PRO	0	0.008	0.009	36.932	0.136	0.136	0.000	0.000	0.000	0.000
372	372	LEU	0	-0.006	-0.004	39.588	-0.094	-0.094	0.000	0.000	0.000	0.000
373	373	ASN	0	-0.013	-0.007	41.888	-0.018	-0.018	0.000	0.000	0.000	0.000
374	374	VAL	0	0.068	0.021	37.021	-0.117	-0.117	0.000	0.000	0.000	0.000
375	375	ALA	0	-0.058	-0.036	39.324	-0.091	-0.091	0.000	0.000	0.000	0.000
376	376	ASP	-1	-0.919	-0.953	41.689	-6.957	-6.957	0.000	0.000	0.000	0.000
377	377	LEU	0	-0.094	-0.025	34.180	-0.100	-0.100	0.000	0.000	0.000	0.000
378	378	ILE	-1	-0.866	-0.922	34.243	-8.257	-8.257	0.000	0.000	0.000	0.000
379	379	A	0	-0.364	-0.298	18.926	0.138	0.138	0.000	0.000	0.000	0.000
380	379	A	-1	-0.532	-0.629	13.082	-18.530	-18.530	0.000	0.000	0.000	0.000
381	380	G	0	-0.369	-0.318	16.271	-0.122	-0.122	0.000	0.000	0.000	0.000
382	380	G	-1	-0.547	-0.631	12.311	-21.020	-21.020	0.000	0.000	0.000	0.000
383	381	A	0	-0.384	-0.306	16.013	0.248	0.248	0.000	0.000	0.000	0.000
384	381	A	-1	-0.586	-0.677	12.086	-21.768	-21.768	0.000	0.000	0.000	0.000
385	382	G	0	-0.326	-0.286	13.024	-0.811	-0.811	0.000	0.000	0.000	0.000
386	382	G	-1	-0.546	-0.660	11.124	-22.216	-22.216	0.000	0.000	0.000	0.000
387	383	A	0	-0.330	-0.296	9.639	-0.593	-0.593	0.000	0.000	0.000	0.000
388	383	A	-1	-0.442	-0.559	6.647	-27.883	-27.883	0.000	0.000	0.000	0.000
389	384	A	0	-0.345	-0.297	6.185	-2.111	-2.111	0.000	0.000	0.000	0.000
395	387	A	0	-0.348	-0.285	5.750	0.534	0.534	0.000	0.000	0.000	0.000
396	387	A	-1	-0.625	-0.716	8.290	-22.404	-22.404	0.000	0.000	0.000	0.000
397	388	G	0	-0.360	-0.293	5.198	2.458	2.458	0.000	0.000	0.000	0.000

Top

Graph

Overview

Highlights

Manual

Support

Interactive mode: IFIE and PIEDA for fragment #399(:389:V6D)