FMO DATABASE

FMODB ID: 72QVK

Calculation Name: 6XKI-A-MD433-91ns

Preferred Name:

Target Type:

Ligand Name: (3s,6z,8e,11s,15r)-15-amino-3-[(1e,3e,5e)-7-(dimethylamino)-2,5-dimethylhepta-1,3,5-trien-1-yl]-9,11-dimethyl-4,12-dioxa-20-thia-21-azabicyclo[16.2.1]henicosa-1(21),6,8,18-tetraene-5,13-dione

ligand 3-letter code: V6D

PDB ID: 6XKI

Chain ID: A

ChEMBL ID:

UniProt ID:

Base Structure: MD

Registration Date: 2023-09-19

Reference: Hironori Saito, Yuma Handa, Mingming Chen, Tilman Schneider-Poetsch, Yuichi Shichino, Mari Takahashi, Daniel Romo, Minoru Yoshida, Alois F�rstner, Takuhiro Ito, Kaori Fukuzawa, Shintaro Iwasaki Pateamine A mediates RNA sequence-selective translation repression by anchoring eIF4A and DDX3 to GNG motifs, To be published.

DOI:

IFIE MAP

IFIE Diagram

Modeling method

Optimization	AMBER14SB
Restraint	OptAll(Heavy atoms were optimized with constraints.)
Protonation	BaseStructure_original
Complement	MOE:Structure Preparation
Water	No
Procedure	Manual calculation

FMO calculation

FMO method	FMO2-MP2/6-31G(d)
Fragmentation	Manual
Number of fragment	400
LigandCharge
Software	ABINIT-MP - Open Ver. 1 Rev. 23Q2 / 20200603(SMP)

Total energy (hartree)

FMO2-HF: Electronic energy	-7591894.666738
FMO2-HF: Nuclear repulsion	7422690.905114
FMO2-HF: Total energy	-169203.761625
FMO2-MP2: Total energy	-169681.325962

3D Structure

Snapshot

Ligand structure

V6D

Ligand Interaction

Ligand binding energy (frag 399-400 : frag 1-398)

IFIE [kcal/mol]	PIEDA [kcal/mol]				Charge transfer value [e]
IFIE SUMIFIE SUM at MP2 level.	ESElectro static interaction energy.	EXExchange-repulsion energy.	CT+mixCharge transfer and mixing terms energy.	DI(MP2)Dispersion energy.	q(I=>J)Charge transfer value from I to J fragments.
-305.364260	-252.908218	40.509138	-22.256665	-70.708516	0.084826

Interactive mode: IFIE and PIEDA for fragment #399(:389:V6D)

Summations of interaction energy for fragment #399(:389:V6D)

IFIE [kcal/mol]	PIEDA [kcal/mol]				Charge transfer value [e]
IFIE SUMIFIE SUM at MP2 level.	ESElectro static interaction energy.	EXExchange-repulsion energy.	CT+mixCharge transfer and mixing terms energy.	DI(MP2)Dispersion energy.	q(I=>J)Charge transfer value from I to J fragments.
-60.123	-22.686	33.958	-17.773	-53.625	-0.079

Interaction energy analysis for fragmet #399(:389:V6D)

Snapshot

IFIE Diagram

Base fragment(s) of PIEDA/IFIE

Single fragment	Multi fragments
	Fragment list

Charge [e] FCHARGE : 0 / q_Mulliken : -0.108 / q_NPA : -0.032

Distance from base fragment(s) [Å]

Dist

Interaction energy by IFIE and PIEDA
[kcal/mol]

| Total | > | ES | > | EX | >
| CT+mix | > | DI(MP2) | >

Fragment charge [e]

FCHARGE q_Mulliken
q_NPA q(I=>J)

Residue

Res # RES

Sort

Graph Options

X Axis Label
Y Axis Max Y Axis Min
Display ES EX CT+mix DI(MP2)

frag_NumFragment number.	Res #Residue number.	RES3-letter code of amino acid residue, ligand and solvent molecule.	FCHARGEFormal charge [e].	q_MullikenFragment charge evaluated by Mulliken charge [e].	q_NPAFragment charge evaluated by natural population analysis(NPA) charge [e].	DISTDistance from Ligand [Å].	TotalIFIE at MP2 level [kcal/mol].	ESElectro static interaction energy by PIEDA [kcal/mol].	EXExchange-repulsion energy by PIEDA [kcal/mol].	CT+mixCharge transfer and mixing terms energy by PIEDA [kcal/mol].	DI(MP2)Dispersion energy by PIEDA [kcal/mol].	q(I=>J)Charge transfer value from I to J fragmens [e].
131	131	PRO	0	0.011	-0.003	3.217	-1.113	-0.119	0.575	-0.293	-1.275	0.001
132	132	GLY	0	0.028	0.027	2.358	-2.411	0.004	4.438	-2.712	-4.141	-0.008
133	133	ARG	1	0.845	0.877	2.483	-2.724	-1.937	1.281	0.410	-2.478	-0.020
134	134	VAL	0	0.040	0.021	5.131	-0.495	-0.333	-0.001	-0.013	-0.148	0.000
135	135	PHE	0	0.046	0.010	2.383	-11.863	-4.676	9.678	-3.988	-12.878	0.014
136	136	ASP	-1	-0.877	-0.909	2.374	-9.806	-6.292	2.371	-2.429	-3.456	-0.013
137	137	MET	0	-0.025	-0.027	3.158	1.946	1.390	0.065	0.946	-0.455	0.000
139	139	ASN	0	-0.076	-0.040	2.973	0.210	1.192	0.110	-0.269	-0.823	-0.001
140	140	ARG	1	0.893	0.956	5.142	1.480	1.529	-0.001	-0.003	-0.045	0.000
167	167	GLN	0	-0.003	0.002	2.787	-7.457	-3.474	5.526	-2.587	-6.923	-0.002
168	168	ILE	0	0.011	-0.004	3.458	-2.283	-1.644	0.080	0.271	-0.990	-0.002
170	170	ASP	-1	-0.837	-0.912	2.666	-8.019	-4.447	1.821	-2.301	-3.092	-0.023
171	171	ILE	0	-0.065	-0.043	2.842	-0.801	0.458	0.205	-0.219	-1.246	0.000
172	172	PHE	0	-0.014	-0.013	4.919	0.318	0.349	-0.001	-0.003	-0.026	0.000
391	385	G	0	-0.335	-0.292	1.973	-2.466	-1.484	2.064	-0.908	-2.138	-0.009
392	385	G	-1	-0.466	-0.585	2.452	-3.267	-1.274	0.421	-0.858	-1.557	-0.006
393	386	A	0	-0.348	-0.295	2.866	-8.687	-0.377	4.779	-2.370	-10.720	-0.015
394	386	A	-1	-0.602	-0.692	2.926	-1.706	-0.572	0.547	-0.447	-1.234	0.005
1	1	GLU	0	-0.060	-0.043	40.237	-0.003	-0.003	0.000	0.000	0.000	0.000
2	2	ILE	0	-0.020	-0.011	39.517	0.000	0.000	0.000	0.000	0.000	0.000
3	3	VAL	0	0.045	0.021	36.642	0.001	0.001	0.000	0.000	0.000	0.000
4	4	ASP	-1	-0.920	-0.954	37.311	-0.038	-0.038	0.000	0.000	0.000	0.000
5	5	SER	0	0.072	0.026	38.445	-0.004	-0.004	0.000	0.000	0.000	0.000
6	6	PHE	0	0.018	-0.021	31.588	0.001	0.001	0.000	0.000	0.000	0.000
7	7	ASP	-1	-0.929	-0.959	35.954	-0.045	-0.045	0.000	0.000	0.000	0.000
8	8	ASP	-1	-0.857	-0.919	38.793	-0.033	-0.033	0.000	0.000	0.000	0.000
9	9	MET	0	-0.192	-0.092	32.103	0.001	0.001	0.000	0.000	0.000	0.000
10	10	ASN	0	-0.044	-0.013	33.926	-0.001	-0.001	0.000	0.000	0.000	0.000
11	11	LEU	0	-0.021	-0.007	30.841	-0.002	-0.002	0.000	0.000	0.000	0.000
12	12	SER	0	0.038	0.012	32.805	0.004	0.004	0.000	0.000	0.000	0.000
13	13	GLU	-1	-0.870	-0.935	34.668	-0.061	-0.061	0.000	0.000	0.000	0.000
14	14	SER	0	-0.059	-0.038	33.912	-0.004	-0.004	0.000	0.000	0.000	0.000
15	15	LEU	0	0.030	0.021	28.539	-0.006	-0.006	0.000	0.000	0.000	0.000
16	16	LEU	0	0.015	0.002	31.976	-0.004	-0.004	0.000	0.000	0.000	0.000
17	17	ARG	1	0.896	0.955	34.767	0.080	0.080	0.000	0.000	0.000	0.000
18	18	GLY	0	0.049	0.024	31.563	-0.001	-0.001	0.000	0.000	0.000	0.000
19	19	ILE	0	-0.026	-0.015	30.428	-0.003	-0.003	0.000	0.000	0.000	0.000
20	20	TYR	0	-0.005	-0.008	32.495	0.000	0.000	0.000	0.000	0.000	0.000
21	21	ALA	0	-0.028	0.000	34.409	0.001	0.001	0.000	0.000	0.000	0.000
22	22	TYR	0	-0.047	-0.030	27.063	-0.004	-0.004	0.000	0.000	0.000	0.000
23	23	GLY	0	-0.012	0.004	32.444	-0.001	-0.001	0.000	0.000	0.000	0.000
24	24	PHE	0	-0.042	-0.014	28.432	0.001	0.001	0.000	0.000	0.000	0.000
25	25	GLU	-1	-0.940	-0.985	34.463	-0.056	-0.056	0.000	0.000	0.000	0.000
26	26	LYS	1	0.964	0.975	36.340	0.046	0.046	0.000	0.000	0.000	0.000
27	27	PRO	0	-0.044	0.010	32.953	-0.003	-0.003	0.000	0.000	0.000	0.000
28	28	SER	0	0.037	0.012	31.758	0.003	0.003	0.000	0.000	0.000	0.000
29	29	ALA	0	0.036	0.002	33.350	0.002	0.002	0.000	0.000	0.000	0.000
30	30	ILE	0	-0.007	-0.016	26.894	0.003	0.003	0.000	0.000	0.000	0.000
31	31	GLN	0	0.031	0.009	28.455	0.004	0.004	0.000	0.000	0.000	0.000
32	32	GLN	0	0.010	0.016	29.910	0.000	0.000	0.000	0.000	0.000	0.000
33	33	ARG	1	0.879	0.936	29.534	0.031	0.031	0.000	0.000	0.000	0.000
34	34	ALA	0	0.026	0.014	25.483	0.003	0.003	0.000	0.000	0.000	0.000
35	35	ILE	0	0.050	0.017	26.872	0.002	0.002	0.000	0.000	0.000	0.000
36	36	LEU	0	0.025	0.022	28.122	0.001	0.001	0.000	0.000	0.000	0.000
37	37	PRO	0	-0.057	-0.030	27.715	0.002	0.002	0.000	0.000	0.000	0.000
38	38	CYS	0	0.031	0.020	23.145	0.001	0.001	0.000	0.000	0.000	0.000
39	39	ILE	0	0.040	0.032	24.782	-0.002	-0.002	0.000	0.000	0.000	0.000
40	40	LYS	1	0.896	0.943	27.083	0.021	0.021	0.000	0.000	0.000	0.000
41	41	GLY	0	0.042	0.038	24.437	0.006	0.006	0.000	0.000	0.000	0.000
42	42	TYR	0	-0.052	-0.013	23.585	0.006	0.006	0.000	0.000	0.000	0.000
43	43	ASP	-1	-0.698	-0.821	20.070	0.000	0.000	0.000	0.000	0.000	0.000
44	44	VAL	0	-0.051	-0.026	21.001	0.004	0.004	0.000	0.000	0.000	0.000
45	45	ILE	0	0.008	0.012	20.135	-0.004	-0.004	0.000	0.000	0.000	0.000
46	46	ALA	0	0.023	-0.018	21.969	0.003	0.003	0.000	0.000	0.000	0.000
47	47	GLN	0	-0.006	-0.003	22.747	-0.002	-0.002	0.000	0.000	0.000	0.000
48	48	ALA	0	-0.026	-0.007	23.781	0.000	0.000	0.000	0.000	0.000	0.000
49	49	GLN	0	0.050	0.020	24.275	-0.009	-0.009	0.000	0.000	0.000	0.000
50	50	SER	0	0.021	0.019	25.265	-0.006	-0.006	0.000	0.000	0.000	0.000
51	51	GLY	0	0.030	0.020	26.578	0.006	0.006	0.000	0.000	0.000	0.000
52	52	THR	0	-0.055	-0.050	27.753	0.004	0.004	0.000	0.000	0.000	0.000
53	53	GLY	0	0.029	0.028	26.780	0.003	0.003	0.000	0.000	0.000	0.000
54	54	LYS	1	0.806	0.892	19.153	0.131	0.131	0.000	0.000	0.000	0.000
55	55	THR	0	0.030	0.002	19.966	-0.003	-0.003	0.000	0.000	0.000	0.000
56	56	ALA	0	0.031	0.012	21.750	-0.003	-0.003	0.000	0.000	0.000	0.000
57	57	THR	0	-0.007	-0.005	23.686	0.006	0.006	0.000	0.000	0.000	0.000
58	58	PHE	0	0.047	0.026	18.028	0.007	0.007	0.000	0.000	0.000	0.000
59	59	ALA	0	-0.001	0.010	21.820	-0.001	-0.001	0.000	0.000	0.000	0.000
60	60	ILE	0	0.021	0.010	22.739	0.001	0.001	0.000	0.000	0.000	0.000
61	61	SER	0	-0.013	-0.035	23.569	0.008	0.008	0.000	0.000	0.000	0.000
62	62	ILE	0	-0.012	-0.005	18.461	0.005	0.005	0.000	0.000	0.000	0.000
63	63	LEU	0	-0.011	-0.010	22.919	0.003	0.003	0.000	0.000	0.000	0.000
64	64	GLN	0	0.038	0.028	25.613	-0.001	-0.001	0.000	0.000	0.000	0.000
65	65	GLN	0	-0.073	-0.043	22.933	0.003	0.003	0.000	0.000	0.000	0.000
66	66	ILE	0	-0.091	-0.038	21.829	0.001	0.001	0.000	0.000	0.000	0.000
67	67	GLU	-1	-0.931	-0.961	25.515	-0.066	-0.066	0.000	0.000	0.000	0.000
68	68	LEU	0	0.026	0.001	26.099	-0.012	-0.012	0.000	0.000	0.000	0.000
69	69	ASP	-1	-0.856	-0.920	26.862	-0.102	-0.102	0.000	0.000	0.000	0.000
70	70	LEU	0	-0.141	-0.061	22.663	-0.001	-0.001	0.000	0.000	0.000	0.000
71	71	LYS	1	0.989	0.990	21.412	0.139	0.139	0.000	0.000	0.000	0.000
72	72	ALA	0	-0.028	-0.008	17.864	-0.026	-0.026	0.000	0.000	0.000	0.000
73	73	THR	0	0.004	-0.008	15.640	0.004	0.004	0.000	0.000	0.000	0.000
74	74	GLN	0	-0.010	-0.003	17.599	0.033	0.033	0.000	0.000	0.000	0.000
75	75	ALA	0	-0.012	-0.006	16.797	0.024	0.024	0.000	0.000	0.000	0.000
76	76	LEU	0	-0.012	0.002	9.305	-0.034	-0.034	0.000	0.000	0.000	0.000
77	77	VAL	0	0.007	0.001	13.381	0.039	0.039	0.000	0.000	0.000	0.000
78	78	LEU	0	-0.003	-0.004	7.007	-0.043	-0.043	0.000	0.000	0.000	0.000
79	79	ALA	0	0.013	0.003	9.802	0.033	0.033	0.000	0.000	0.000	0.000
80	80	PRO	0	0.044	0.014	8.725	-0.083	-0.083	0.000	0.000	0.000	0.000
81	81	THR	0	0.018	0.005	8.893	-0.121	-0.121	0.000	0.000	0.000	0.000
82	82	ARG	1	0.872	0.904	8.109	1.079	1.079	0.000	0.000	0.000	0.000
83	83	GLU	-1	-0.771	-0.871	11.664	-0.409	-0.409	0.000	0.000	0.000	0.000
84	84	LEU	0	-0.011	0.002	13.858	0.043	0.043	0.000	0.000	0.000	0.000
85	85	ALA	0	0.010	0.007	12.343	0.035	0.035	0.000	0.000	0.000	0.000
86	86	GLN	0	0.035	0.007	14.479	0.040	0.040	0.000	0.000	0.000	0.000
87	87	GLN	0	-0.034	-0.005	17.354	0.024	0.024	0.000	0.000	0.000	0.000
88	88	ILE	0	0.024	0.005	15.283	0.023	0.023	0.000	0.000	0.000	0.000
89	89	GLN	0	0.030	0.005	18.273	0.013	0.013	0.000	0.000	0.000	0.000
90	90	LYS	1	0.917	0.949	19.928	0.258	0.258	0.000	0.000	0.000	0.000
91	91	VAL	0	-0.003	0.025	22.558	0.015	0.015	0.000	0.000	0.000	0.000
92	92	VAL	0	0.010	-0.012	19.643	0.013	0.013	0.000	0.000	0.000	0.000
93	93	MET	0	-0.005	0.016	22.307	0.006	0.006	0.000	0.000	0.000	0.000
94	94	ALA	0	-0.008	0.016	24.945	0.008	0.008	0.000	0.000	0.000	0.000
95	95	LEU	0	-0.047	-0.028	25.537	0.011	0.011	0.000	0.000	0.000	0.000
96	96	GLY	0	0.017	0.000	26.464	0.009	0.009	0.000	0.000	0.000	0.000
97	97	ASP	-1	-0.953	-0.959	27.435	-0.127	-0.127	0.000	0.000	0.000	0.000
98	98	TYR	0	0.000	-0.023	29.912	0.004	0.004	0.000	0.000	0.000	0.000
99	99	MET	0	-0.051	-0.025	29.264	0.004	0.004	0.000	0.000	0.000	0.000
100	100	GLY	0	0.010	0.023	29.303	0.003	0.003	0.000	0.000	0.000	0.000
101	101	ALA	0	-0.058	-0.024	25.065	-0.006	-0.006	0.000	0.000	0.000	0.000
102	102	SER	0	-0.046	-0.055	22.067	-0.008	-0.008	0.000	0.000	0.000	0.000
103	103	CYS	0	-0.066	-0.046	18.285	-0.002	-0.002	0.000	0.000	0.000	0.000
104	104	HIS	0	0.010	-0.008	13.844	0.048	0.048	0.000	0.000	0.000	0.000
105	105	ALA	0	0.020	0.013	14.581	-0.010	-0.010	0.000	0.000	0.000	0.000
106	106	CYS	0	-0.107	-0.032	10.397	-0.083	-0.083	0.000	0.000	0.000	0.000
107	107	ILE	0	0.010	0.000	9.416	-0.036	-0.036	0.000	0.000	0.000	0.000
108	108	GLY	0	0.013	0.012	7.839	-0.031	-0.031	0.000	0.000	0.000	0.000
109	109	GLY	0	0.025	0.006	8.470	0.100	0.100	0.000	0.000	0.000	0.000
110	110	THR	0	-0.027	0.001	11.100	0.077	0.077	0.000	0.000	0.000	0.000
111	111	ASN	0	0.031	0.001	11.592	-0.121	-0.121	0.000	0.000	0.000	0.000
112	112	VAL	0	0.112	0.058	6.772	0.085	0.085	0.000	0.000	0.000	0.000
113	113	ARG	1	0.950	0.973	10.225	0.464	0.464	0.000	0.000	0.000	0.000
114	114	ALA	0	-0.018	-0.022	12.562	0.053	0.053	0.000	0.000	0.000	0.000
115	115	GLU	-1	-0.793	-0.876	10.345	-0.718	-0.718	0.000	0.000	0.000	0.000
116	116	VAL	0	0.021	0.008	9.781	0.035	0.035	0.000	0.000	0.000	0.000
117	117	GLN	0	-0.032	-0.002	12.659	0.063	0.063	0.000	0.000	0.000	0.000
118	118	LYS	1	0.923	0.955	16.033	0.495	0.495	0.000	0.000	0.000	0.000
119	119	LEU	0	0.057	0.023	11.837	0.033	0.033	0.000	0.000	0.000	0.000
120	120	GLN	0	-0.060	-0.022	15.851	0.023	0.023	0.000	0.000	0.000	0.000
121	121	MET	0	-0.090	-0.042	17.474	0.043	0.043	0.000	0.000	0.000	0.000
122	122	GLU	-1	-0.889	-0.927	18.963	-0.234	-0.234	0.000	0.000	0.000	0.000
123	123	ALA	0	-0.061	-0.018	18.720	0.022	0.022	0.000	0.000	0.000	0.000
124	124	PRO	0	0.034	0.038	17.011	0.021	0.021	0.000	0.000	0.000	0.000
125	125	HIS	0	0.076	0.036	18.704	-0.023	-0.023	0.000	0.000	0.000	0.000
126	126	ILE	0	-0.046	-0.028	17.229	0.013	0.013	0.000	0.000	0.000	0.000
127	127	ILE	0	0.016	0.005	11.659	-0.035	-0.035	0.000	0.000	0.000	0.000
128	128	VAL	0	0.009	0.011	13.384	0.035	0.035	0.000	0.000	0.000	0.000
129	129	GLY	0	0.023	0.002	10.201	-0.051	-0.051	0.000	0.000	0.000	0.000
130	130	THR	0	-0.012	-0.015	6.274	0.148	0.148	0.000	0.000	0.000	0.000
138	138	LEU	0	-0.014	0.004	6.150	0.339	0.339	0.000	0.000	0.000	0.000
141	141	ARG	1	0.866	0.932	7.223	0.289	0.289	0.000	0.000	0.000	0.000
142	142	TYR	0	0.036	0.020	9.688	0.099	0.099	0.000	0.000	0.000	0.000
143	143	LEU	0	0.022	0.037	10.095	0.067	0.067	0.000	0.000	0.000	0.000
144	144	SER	0	0.016	-0.013	11.065	0.005	0.005	0.000	0.000	0.000	0.000
145	145	PRO	0	0.032	0.007	11.761	0.002	0.002	0.000	0.000	0.000	0.000
146	146	LYS	1	0.892	0.960	14.370	0.002	0.002	0.000	0.000	0.000	0.000
147	147	TYR	0	-0.010	-0.027	17.453	0.007	0.007	0.000	0.000	0.000	0.000
148	148	ILE	0	-0.016	0.018	12.719	-0.008	-0.008	0.000	0.000	0.000	0.000
149	149	LYS	1	0.891	0.964	16.906	0.103	0.103	0.000	0.000	0.000	0.000
150	150	MET	0	-0.008	-0.001	17.767	0.013	0.013	0.000	0.000	0.000	0.000
151	151	PHE	0	-0.004	-0.005	8.794	-0.029	-0.029	0.000	0.000	0.000	0.000
152	152	VAL	0	0.009	-0.003	13.917	0.026	0.026	0.000	0.000	0.000	0.000
153	153	LEU	0	0.007	0.007	10.348	-0.019	-0.019	0.000	0.000	0.000	0.000
154	154	ASP	-1	-0.782	-0.898	13.674	-0.132	-0.132	0.000	0.000	0.000	0.000
155	155	GLU	-1	-0.837	-0.911	14.122	-0.164	-0.164	0.000	0.000	0.000	0.000
156	156	ALA	0	-0.016	-0.015	13.656	0.005	0.005	0.000	0.000	0.000	0.000
157	157	ASP	-1	-0.757	-0.827	13.892	-0.043	-0.043	0.000	0.000	0.000	0.000
158	158	GLU	-1	-0.887	-0.936	11.830	-0.118	-0.118	0.000	0.000	0.000	0.000
159	159	MET	0	-0.057	-0.015	7.529	0.010	0.010	0.000	0.000	0.000	0.000
160	160	LEU	0	-0.038	-0.023	9.829	0.104	0.104	0.000	0.000	0.000	0.000
161	161	SER	0	0.010	0.009	11.172	0.009	0.009	0.000	0.000	0.000	0.000
162	162	ARG	1	0.795	0.864	10.365	-0.059	-0.059	0.000	0.000	0.000	0.000
163	163	GLY	0	0.054	0.052	7.955	0.088	0.088	0.000	0.000	0.000	0.000
164	164	PHE	0	0.012	-0.005	5.292	0.100	0.100	0.000	0.000	0.000	0.000
165	165	LYS	1	0.930	0.983	6.942	0.137	0.137	0.000	0.000	0.000	0.000
166	166	ASP	-1	-0.888	-0.964	5.200	0.235	0.235	0.000	0.000	0.000	0.000
169	169	TYR	0	-0.055	-0.032	6.261	-0.296	-0.296	0.000	0.000	0.000	0.000
173	173	GLN	0	0.001	0.002	7.161	0.194	0.194	0.000	0.000	0.000	0.000
174	174	LYS	1	0.839	0.934	6.152	-1.676	-1.676	0.000	0.000	0.000	0.000
175	175	LEU	0	-0.009	0.006	8.982	-0.014	-0.014	0.000	0.000	0.000	0.000
176	176	ASN	0	0.030	0.014	11.675	0.093	0.093	0.000	0.000	0.000	0.000
177	177	SER	0	0.015	-0.008	15.364	-0.025	-0.025	0.000	0.000	0.000	0.000
178	178	ASN	0	-0.081	-0.052	17.515	0.001	0.001	0.000	0.000	0.000	0.000
179	179	THR	0	0.001	0.025	14.373	-0.009	-0.009	0.000	0.000	0.000	0.000
180	180	GLN	0	0.015	0.004	17.251	0.010	0.010	0.000	0.000	0.000	0.000
181	181	VAL	0	-0.037	-0.029	14.530	-0.016	-0.016	0.000	0.000	0.000	0.000
182	182	VAL	0	-0.012	-0.013	16.554	0.008	0.008	0.000	0.000	0.000	0.000
183	183	LEU	0	0.013	0.003	15.285	-0.006	-0.006	0.000	0.000	0.000	0.000
184	184	LEU	0	-0.009	-0.011	17.588	0.006	0.006	0.000	0.000	0.000	0.000
185	185	SER	0	-0.024	-0.047	17.908	-0.013	-0.013	0.000	0.000	0.000	0.000
186	186	ALA	0	0.043	0.032	20.105	0.009	0.009	0.000	0.000	0.000	0.000
187	187	THR	0	-0.007	0.002	20.045	0.004	0.004	0.000	0.000	0.000	0.000
188	188	MET	0	-0.029	-0.023	20.032	0.001	0.001	0.000	0.000	0.000	0.000
189	189	PRO	0	0.058	0.047	19.254	0.005	0.005	0.000	0.000	0.000	0.000
190	190	SER	0	-0.032	-0.028	21.642	0.005	0.005	0.000	0.000	0.000	0.000
191	191	ASP	-1	-0.883	-0.934	20.131	0.037	0.037	0.000	0.000	0.000	0.000
192	192	VAL	0	0.028	0.015	16.326	0.009	0.009	0.000	0.000	0.000	0.000
193	193	LEU	0	-0.015	-0.011	17.893	0.007	0.007	0.000	0.000	0.000	0.000
194	194	GLU	-1	-0.909	-0.950	19.808	0.050	0.050	0.000	0.000	0.000	0.000
195	195	VAL	0	-0.044	-0.018	13.561	0.009	0.009	0.000	0.000	0.000	0.000
196	196	THR	0	-0.010	-0.022	15.677	0.004	0.004	0.000	0.000	0.000	0.000
197	197	LYS	1	0.907	0.958	16.807	-0.053	-0.053	0.000	0.000	0.000	0.000
198	198	LYS	1	0.914	0.960	14.309	-0.142	-0.142	0.000	0.000	0.000	0.000
199	199	PHE	0	-0.012	-0.005	12.800	0.011	0.011	0.000	0.000	0.000	0.000
200	200	MET	0	-0.057	-0.006	14.813	-0.012	-0.012	0.000	0.000	0.000	0.000
201	201	ARG	1	0.731	0.835	17.749	-0.019	-0.019	0.000	0.000	0.000	0.000
202	202	ASP	-1	-0.975	-0.981	21.218	0.024	0.024	0.000	0.000	0.000	0.000
203	203	PRO	0	-0.009	0.009	21.048	-0.004	-0.004	0.000	0.000	0.000	0.000
204	204	ILE	0	0.028	0.007	23.605	0.001	0.001	0.000	0.000	0.000	0.000
205	205	ARG	1	0.952	0.975	22.898	-0.023	-0.023	0.000	0.000	0.000	0.000
206	206	ILE	0	-0.037	-0.012	26.253	0.000	0.000	0.000	0.000	0.000	0.000
207	207	LEU	0	-0.020	-0.018	25.031	-0.003	-0.003	0.000	0.000	0.000	0.000
208	208	VAL	0	0.008	0.001	27.548	0.000	0.000	0.000	0.000	0.000	0.000
209	209	LYS	1	0.944	0.983	28.691	0.014	0.014	0.000	0.000	0.000	0.000
210	210	LYS	1	0.970	0.979	27.059	0.004	0.004	0.000	0.000	0.000	0.000
211	211	GLU	-1	-0.888	-0.945	30.229	-0.019	-0.019	0.000	0.000	0.000	0.000
212	212	GLU	-1	-0.983	-0.996	32.302	-0.027	-0.027	0.000	0.000	0.000	0.000
213	213	LEU	0	-0.074	-0.023	26.310	-0.003	-0.003	0.000	0.000	0.000	0.000
214	214	THR	0	-0.017	-0.010	29.122	-0.007	-0.007	0.000	0.000	0.000	0.000
215	215	LEU	0	-0.019	-0.007	27.226	0.000	0.000	0.000	0.000	0.000	0.000
216	216	GLU	-1	-0.876	-0.945	31.589	-0.046	-0.046	0.000	0.000	0.000	0.000
217	217	GLY	0	-0.079	-0.033	33.280	0.001	0.001	0.000	0.000	0.000	0.000
218	218	ILE	0	-0.031	-0.015	29.286	-0.003	-0.003	0.000	0.000	0.000	0.000
219	219	ARG	1	0.959	0.992	33.155	0.053	0.053	0.000	0.000	0.000	0.000
220	220	GLN	0	0.060	0.036	31.026	-0.002	-0.002	0.000	0.000	0.000	0.000
221	221	PHE	0	0.030	0.014	34.348	0.004	0.004	0.000	0.000	0.000	0.000
222	222	TYR	0	-0.017	-0.009	33.923	-0.004	-0.004	0.000	0.000	0.000	0.000
223	223	ILE	0	0.052	0.024	35.239	0.001	0.001	0.000	0.000	0.000	0.000
224	224	ASN	0	-0.031	-0.022	36.065	-0.001	-0.001	0.000	0.000	0.000	0.000
225	225	VAL	0	0.040	0.012	35.011	0.000	0.000	0.000	0.000	0.000	0.000
226	226	GLU	-1	-0.825	-0.883	38.070	-0.024	-0.024	0.000	0.000	0.000	0.000
227	227	ARG	1	0.889	0.941	36.495	0.028	0.028	0.000	0.000	0.000	0.000
228	228	GLU	-1	-0.720	-0.848	29.736	-0.062	-0.062	0.000	0.000	0.000	0.000
229	229	GLU	-1	-0.968	-0.991	33.655	-0.046	-0.046	0.000	0.000	0.000	0.000
230	230	TRP	0	0.000	-0.010	36.047	0.000	0.000	0.000	0.000	0.000	0.000
231	231	LYS	1	0.811	0.918	28.476	0.064	0.064	0.000	0.000	0.000	0.000
232	232	LEU	0	0.029	0.014	33.211	-0.004	-0.004	0.000	0.000	0.000	0.000
233	233	ASP	-1	-0.845	-0.924	34.669	-0.050	-0.050	0.000	0.000	0.000	0.000
234	234	THR	0	-0.002	-0.002	36.387	0.001	0.001	0.000	0.000	0.000	0.000
235	235	LEU	0	-0.033	-0.021	31.212	-0.001	-0.001	0.000	0.000	0.000	0.000
236	236	CYS	0	-0.103	-0.062	35.397	-0.003	-0.003	0.000	0.000	0.000	0.000
237	237	ASP	-1	-0.877	-0.913	38.008	-0.049	-0.049	0.000	0.000	0.000	0.000
238	238	LEU	0	-0.048	-0.028	34.390	0.000	0.000	0.000	0.000	0.000	0.000
239	239	TYR	0	0.004	-0.039	32.527	-0.004	-0.004	0.000	0.000	0.000	0.000
240	240	GLU	-1	-0.919	-0.932	37.343	-0.062	-0.062	0.000	0.000	0.000	0.000
241	241	THR	0	0.017	-0.003	37.707	0.001	0.001	0.000	0.000	0.000	0.000
242	242	LEU	0	-0.049	-0.026	32.663	-0.003	-0.003	0.000	0.000	0.000	0.000
243	243	THR	0	-0.011	-0.003	35.640	-0.006	-0.006	0.000	0.000	0.000	0.000
244	244	ILE	0	-0.066	-0.021	38.372	-0.001	-0.001	0.000	0.000	0.000	0.000
245	245	THR	0	-0.048	-0.009	35.418	-0.003	-0.003	0.000	0.000	0.000	0.000
246	246	GLN	0	-0.010	-0.004	28.325	0.004	0.004	0.000	0.000	0.000	0.000
247	247	ALA	0	-0.008	-0.006	30.026	0.002	0.002	0.000	0.000	0.000	0.000
248	248	VAL	0	-0.029	-0.006	23.434	-0.008	-0.008	0.000	0.000	0.000	0.000
249	249	ILE	0	0.015	0.007	25.944	0.011	0.011	0.000	0.000	0.000	0.000
250	250	PHE	0	-0.006	-0.002	19.890	-0.010	-0.010	0.000	0.000	0.000	0.000
251	251	ILE	0	-0.040	-0.028	22.202	0.016	0.016	0.000	0.000	0.000	0.000
252	252	ASN	0	-0.004	-0.022	20.311	-0.025	-0.025	0.000	0.000	0.000	0.000
253	253	THR	0	-0.038	-0.022	18.764	0.004	0.004	0.000	0.000	0.000	0.000
254	254	ARG	1	0.911	0.927	11.567	0.417	0.417	0.000	0.000	0.000	0.000
255	255	ARG	1	0.969	0.988	19.083	0.070	0.070	0.000	0.000	0.000	0.000
256	256	LYS	1	0.777	0.862	22.031	0.079	0.079	0.000	0.000	0.000	0.000
257	257	VAL	0	0.066	0.032	21.096	0.007	0.007	0.000	0.000	0.000	0.000
258	258	ASP	-1	-0.834	-0.883	21.826	-0.168	-0.168	0.000	0.000	0.000	0.000
259	259	TRP	0	-0.003	-0.007	24.581	0.008	0.008	0.000	0.000	0.000	0.000
260	260	LEU	0	-0.012	-0.008	27.123	0.006	0.006	0.000	0.000	0.000	0.000
261	261	THR	0	-0.010	-0.032	25.840	0.001	0.001	0.000	0.000	0.000	0.000
262	262	GLU	-1	-0.971	-0.969	28.428	-0.082	-0.082	0.000	0.000	0.000	0.000
263	263	LYS	1	0.891	0.933	30.737	0.068	0.068	0.000	0.000	0.000	0.000
264	264	MET	0	-0.014	-0.010	31.736	0.006	0.006	0.000	0.000	0.000	0.000
265	265	HIS	0	0.021	0.016	32.389	0.000	0.000	0.000	0.000	0.000	0.000
266	266	ALA	0	-0.037	-0.016	34.380	0.003	0.003	0.000	0.000	0.000	0.000
267	267	ARG	1	0.806	0.900	36.833	0.061	0.061	0.000	0.000	0.000	0.000
268	268	ASP	-1	-0.903	-0.940	38.284	-0.065	-0.065	0.000	0.000	0.000	0.000
269	269	PHE	0	-0.026	-0.004	35.503	-0.001	-0.001	0.000	0.000	0.000	0.000
270	270	THR	0	-0.013	-0.009	33.493	-0.004	-0.004	0.000	0.000	0.000	0.000
271	271	VAL	0	-0.003	0.006	28.890	-0.001	-0.001	0.000	0.000	0.000	0.000
272	272	SER	0	-0.012	-0.005	26.224	-0.008	-0.008	0.000	0.000	0.000	0.000
273	273	ALA	0	0.036	0.018	23.182	0.005	0.005	0.000	0.000	0.000	0.000
274	274	MET	0	-0.013	-0.007	18.075	-0.021	-0.021	0.000	0.000	0.000	0.000
275	275	HIS	0	-0.034	-0.029	16.786	-0.017	-0.017	0.000	0.000	0.000	0.000
276	276	GLY	0	0.024	-0.010	13.276	-0.013	-0.013	0.000	0.000	0.000	0.000
277	277	ASP	-1	-0.878	-0.921	13.601	-0.306	-0.306	0.000	0.000	0.000	0.000
278	278	MET	0	-0.083	-0.008	16.059	-0.001	-0.001	0.000	0.000	0.000	0.000
279	279	ASP	-1	-0.865	-0.932	15.069	-0.426	-0.426	0.000	0.000	0.000	0.000
280	280	GLN	0	-0.040	-0.045	13.341	-0.046	-0.046	0.000	0.000	0.000	0.000
281	281	LYS	1	0.918	0.948	15.630	0.322	0.322	0.000	0.000	0.000	0.000
282	282	GLU	-1	-0.876	-0.929	18.943	-0.224	-0.224	0.000	0.000	0.000	0.000
283	283	ARG	1	0.783	0.852	11.251	0.629	0.629	0.000	0.000	0.000	0.000
284	284	ASP	-1	-0.877	-0.937	17.758	-0.368	-0.368	0.000	0.000	0.000	0.000
285	285	VAL	0	-0.082	-0.049	19.883	0.025	0.025	0.000	0.000	0.000	0.000
286	286	ILE	0	0.035	0.023	21.040	0.020	0.020	0.000	0.000	0.000	0.000
287	287	MET	0	0.000	0.010	18.903	0.026	0.026	0.000	0.000	0.000	0.000
288	288	ARG	1	0.800	0.893	22.159	0.206	0.206	0.000	0.000	0.000	0.000
289	289	GLU	-1	-0.792	-0.875	24.956	-0.148	-0.148	0.000	0.000	0.000	0.000
290	290	PHE	0	0.029	0.030	23.892	0.011	0.011	0.000	0.000	0.000	0.000
291	291	ARG	1	0.853	0.902	20.362	0.230	0.230	0.000	0.000	0.000	0.000
292	292	SER	0	-0.085	-0.059	26.723	0.011	0.011	0.000	0.000	0.000	0.000
293	293	GLY	0	-0.018	-0.008	29.452	0.008	0.008	0.000	0.000	0.000	0.000
294	294	SER	0	-0.031	0.006	30.863	0.008	0.008	0.000	0.000	0.000	0.000
295	295	SER	0	-0.014	-0.018	27.257	0.007	0.007	0.000	0.000	0.000	0.000
296	296	ARG	1	0.922	0.951	29.778	0.089	0.089	0.000	0.000	0.000	0.000
297	297	VAL	0	0.041	0.022	29.238	0.003	0.003	0.000	0.000	0.000	0.000
298	298	LEU	0	-0.027	0.000	22.064	-0.007	-0.007	0.000	0.000	0.000	0.000
299	299	ILE	0	0.012	0.008	24.485	0.004	0.004	0.000	0.000	0.000	0.000
300	300	THR	0	-0.063	-0.054	19.343	-0.021	-0.021	0.000	0.000	0.000	0.000
301	301	THR	0	0.064	0.009	16.105	0.024	0.024	0.000	0.000	0.000	0.000
302	302	ASP	-1	-0.807	-0.912	15.767	-0.152	-0.152	0.000	0.000	0.000	0.000
303	303	LEU	0	-0.041	0.010	12.530	-0.015	-0.015	0.000	0.000	0.000	0.000
304	304	LEU	0	-0.010	-0.018	14.764	-0.016	-0.016	0.000	0.000	0.000	0.000
305	305	ALA	0	0.017	0.019	17.036	0.024	0.024	0.000	0.000	0.000	0.000
306	306	ARG	1	0.841	0.888	14.698	0.143	0.143	0.000	0.000	0.000	0.000
307	307	GLY	0	0.031	0.016	17.094	-0.023	-0.023	0.000	0.000	0.000	0.000
308	308	ILE	0	-0.040	-0.017	17.094	0.009	0.009	0.000	0.000	0.000	0.000
309	309	ASP	-1	-0.843	-0.897	20.234	-0.119	-0.119	0.000	0.000	0.000	0.000
310	310	VAL	0	0.008	0.001	23.718	-0.009	-0.009	0.000	0.000	0.000	0.000
311	311	GLN	0	0.011	-0.003	26.335	0.011	0.011	0.000	0.000	0.000	0.000
312	312	GLN	0	0.007	-0.011	29.872	0.005	0.005	0.000	0.000	0.000	0.000
313	313	VAL	0	-0.031	0.012	26.815	0.005	0.005	0.000	0.000	0.000	0.000
314	314	SER	0	0.032	0.006	30.257	0.002	0.002	0.000	0.000	0.000	0.000
315	315	LEU	0	0.028	0.005	31.997	0.002	0.002	0.000	0.000	0.000	0.000
316	316	VAL	0	-0.022	-0.013	25.928	-0.009	-0.009	0.000	0.000	0.000	0.000
317	317	ILE	0	-0.004	-0.001	28.338	0.008	0.008	0.000	0.000	0.000	0.000
318	318	ASN	0	0.013	0.007	25.270	-0.017	-0.017	0.000	0.000	0.000	0.000
319	319	TYR	0	0.068	0.018	27.261	0.009	0.009	0.000	0.000	0.000	0.000
320	320	ASP	-1	-0.768	-0.855	24.453	-0.078	-0.078	0.000	0.000	0.000	0.000
321	321	LEU	0	0.025	0.015	25.539	-0.007	-0.007	0.000	0.000	0.000	0.000
322	322	PRO	0	-0.008	0.019	21.903	0.001	0.001	0.000	0.000	0.000	0.000
323	323	THR	0	0.036	0.004	21.501	0.010	0.010	0.000	0.000	0.000	0.000
324	324	ASN	0	-0.018	-0.007	18.621	0.003	0.003	0.000	0.000	0.000	0.000
325	325	ARG	1	0.973	0.997	21.462	0.021	0.021	0.000	0.000	0.000	0.000
326	326	GLU	-1	-0.812	-0.917	20.489	-0.030	-0.030	0.000	0.000	0.000	0.000
327	327	ASN	0	-0.047	-0.044	18.890	-0.016	-0.016	0.000	0.000	0.000	0.000
328	328	TYR	0	-0.016	-0.011	20.569	-0.012	-0.012	0.000	0.000	0.000	0.000
329	329	ILE	0	0.013	0.004	23.599	-0.006	-0.006	0.000	0.000	0.000	0.000
330	330	HIS	0	-0.083	-0.039	19.614	-0.016	-0.016	0.000	0.000	0.000	0.000
331	331	ARG	1	0.822	0.892	19.948	0.114	0.114	0.000	0.000	0.000	0.000
332	332	ILE	0	0.004	-0.009	22.931	-0.004	-0.004	0.000	0.000	0.000	0.000
333	333	GLY	0	0.003	0.006	25.126	0.003	0.003	0.000	0.000	0.000	0.000
334	334	ARG	1	0.781	0.892	21.112	0.152	0.152	0.000	0.000	0.000	0.000
335	335	GLY	0	0.005	0.009	25.202	-0.003	-0.003	0.000	0.000	0.000	0.000
336	336	GLY	0	0.024	0.001	28.997	0.003	0.003	0.000	0.000	0.000	0.000
337	337	ARG	1	0.776	0.901	26.924	0.119	0.119	0.000	0.000	0.000	0.000
338	338	PHE	0	-0.028	-0.039	30.581	0.004	0.004	0.000	0.000	0.000	0.000
339	339	GLY	0	0.005	0.002	33.002	0.003	0.003	0.000	0.000	0.000	0.000
340	340	ARG	1	0.903	0.976	33.499	0.100	0.100	0.000	0.000	0.000	0.000
341	341	LYS	1	0.963	0.994	34.991	0.059	0.059	0.000	0.000	0.000	0.000
342	342	GLY	0	0.069	0.031	32.853	-0.004	-0.004	0.000	0.000	0.000	0.000
343	343	VAL	0	-0.075	-0.031	32.820	0.006	0.006	0.000	0.000	0.000	0.000
344	344	ALA	0	0.031	0.017	30.361	-0.006	-0.006	0.000	0.000	0.000	0.000
345	345	ILE	0	0.016	0.002	31.211	0.006	0.006	0.000	0.000	0.000	0.000
346	346	ASN	0	-0.017	-0.017	29.387	-0.009	-0.009	0.000	0.000	0.000	0.000
347	347	MET	0	-0.017	-0.004	30.759	0.003	0.003	0.000	0.000	0.000	0.000
348	348	VAL	0	-0.017	-0.005	31.484	-0.001	-0.001	0.000	0.000	0.000	0.000
349	349	THR	0	-0.024	-0.040	32.147	0.004	0.004	0.000	0.000	0.000	0.000
350	350	GLU	-1	-0.871	-0.957	34.651	-0.018	-0.018	0.000	0.000	0.000	0.000
351	351	GLU	-1	-0.954	-0.966	31.606	-0.013	-0.013	0.000	0.000	0.000	0.000
352	352	ASP	-1	-0.851	-0.887	29.534	-0.044	-0.044	0.000	0.000	0.000	0.000
353	353	LYS	1	0.798	0.878	31.800	0.024	0.024	0.000	0.000	0.000	0.000
354	354	ARG	1	0.817	0.890	32.000	0.013	0.013	0.000	0.000	0.000	0.000
355	355	THR	0	0.043	0.017	27.128	0.001	0.001	0.000	0.000	0.000	0.000
356	356	LEU	0	0.037	0.021	30.271	-0.002	-0.002	0.000	0.000	0.000	0.000
357	357	ARG	1	0.954	0.975	32.482	0.020	0.020	0.000	0.000	0.000	0.000
358	358	ASP	-1	-0.858	-0.908	29.695	-0.012	-0.012	0.000	0.000	0.000	0.000
359	359	ILE	0	-0.042	-0.012	27.645	0.001	0.001	0.000	0.000	0.000	0.000
360	360	GLU	-1	-0.831	-0.902	30.136	-0.028	-0.028	0.000	0.000	0.000	0.000
361	361	THR	0	-0.062	-0.035	33.049	0.003	0.003	0.000	0.000	0.000	0.000
362	362	PHE	0	-0.074	-0.040	25.491	0.004	0.004	0.000	0.000	0.000	0.000
363	363	TYR	0	-0.022	-0.042	24.978	-0.001	-0.001	0.000	0.000	0.000	0.000
364	364	ASN	0	-0.045	-0.015	31.437	-0.001	-0.001	0.000	0.000	0.000	0.000
365	365	THR	0	-0.028	-0.009	34.361	0.001	0.001	0.000	0.000	0.000	0.000
366	366	SER	0	-0.066	-0.042	34.842	-0.002	-0.002	0.000	0.000	0.000	0.000
367	367	ILE	0	-0.029	-0.006	31.802	-0.003	-0.003	0.000	0.000	0.000	0.000
368	368	GLU	-1	-0.893	-0.945	36.260	-0.031	-0.031	0.000	0.000	0.000	0.000
369	369	GLU	-1	-0.974	-0.991	38.320	-0.037	-0.037	0.000	0.000	0.000	0.000
370	370	MET	0	-0.052	-0.026	37.646	-0.003	-0.003	0.000	0.000	0.000	0.000
371	371	PRO	0	-0.013	-0.004	39.812	0.002	0.002	0.000	0.000	0.000	0.000
372	372	LEU	0	0.025	0.015	42.183	-0.001	-0.001	0.000	0.000	0.000	0.000
373	373	ASN	0	-0.009	-0.014	44.202	-0.003	-0.003	0.000	0.000	0.000	0.000
374	374	VAL	0	0.038	0.014	37.929	0.000	0.000	0.000	0.000	0.000	0.000
375	375	ALA	0	0.003	-0.010	40.543	-0.003	-0.003	0.000	0.000	0.000	0.000
376	376	ASP	-1	-0.978	-0.981	42.147	-0.046	-0.046	0.000	0.000	0.000	0.000
377	377	LEU	0	-0.068	-0.027	38.386	0.001	0.001	0.000	0.000	0.000	0.000
378	378	ILE	-1	-0.974	-0.982	37.467	-0.065	-0.065	0.000	0.000	0.000	0.000
379	379	A	0	-0.374	-0.311	17.863	-0.012	-0.012	0.000	0.000	0.000	0.000
380	379	A	-1	-0.522	-0.619	13.427	0.237	0.237	0.000	0.000	0.000	0.000
381	380	G	0	-0.368	-0.318	16.367	0.001	0.001	0.000	0.000	0.000	0.000
382	380	G	-1	-0.510	-0.608	13.699	0.120	0.120	0.000	0.000	0.000	0.000
383	381	A	0	-0.377	-0.315	15.289	-0.011	-0.011	0.000	0.000	0.000	0.000
384	381	A	-1	-0.631	-0.685	15.454	-0.036	-0.036	0.000	0.000	0.000	0.000
385	382	G	0	-0.359	-0.311	12.027	0.052	0.052	0.000	0.000	0.000	0.000
386	382	G	-1	-0.525	-0.649	15.407	-0.153	-0.153	0.000	0.000	0.000	0.000
387	383	A	0	-0.335	-0.299	8.967	-0.033	-0.033	0.000	0.000	0.000	0.000
388	383	A	-1	-0.467	-0.572	11.005	-0.345	-0.345	0.000	0.000	0.000	0.000
389	384	A	0	-0.355	-0.307	5.646	-0.176	-0.176	0.000	0.000	0.000	0.000
390	384	A	-1	-0.440	-0.570	7.220	-0.671	-0.671	0.000	0.000	0.000	0.000
395	387	G	0	-0.356	-0.302	6.814	0.464	0.464	0.000	0.000	0.000	0.000
396	387	G	-1	-0.590	-0.675	6.346	-1.043	-1.043	0.000	0.000	0.000	0.000
397	388	G	0	-0.325	-0.279	9.547	-0.206	-0.206	0.000	0.000	0.000	0.000
398	388	G	0	0.253	0.241	11.424	0.051	0.051	0.000	0.000	0.000	0.000

Top

Graph

Overview

Highlights

Manual

Support

Interactive mode: IFIE and PIEDA for fragment #399(:389:V6D)