FMO DATABASE

FMODB ID: 85RVY

Calculation Name: 6XKI-A-MD433-82ns

Preferred Name:

Target Type:

Ligand Name: (3s,6z,8e,11s,15r)-15-amino-3-[(1e,3e,5e)-7-(dimethylamino)-2,5-dimethylhepta-1,3,5-trien-1-yl]-9,11-dimethyl-4,12-dioxa-20-thia-21-azabicyclo[16.2.1]henicosa-1(21),6,8,18-tetraene-5,13-dione

ligand 3-letter code: V6D

PDB ID: 6XKI

Chain ID: A

ChEMBL ID:

UniProt ID:

Base Structure: MD

Registration Date: 2023-09-19

Reference: Hironori Saito, Yuma Handa, Mingming Chen, Tilman Schneider-Poetsch, Yuichi Shichino, Mari Takahashi, Daniel Romo, Minoru Yoshida, Alois F�rstner, Takuhiro Ito, Kaori Fukuzawa, Shintaro Iwasaki Pateamine A mediates RNA sequence-selective translation repression by anchoring eIF4A and DDX3 to GNG motifs, To be published.

DOI:

IFIE MAP

IFIE Diagram

Modeling method

Optimization	AMBER14SB
Restraint	OptAll(Heavy atoms were optimized with constraints.)
Protonation	BaseStructure_original
Complement	MOE:Structure Preparation
Water	No
Procedure	Manual calculation

FMO calculation

FMO method	FMO2-MP2/6-31G(d)
Fragmentation	Manual
Number of fragment	400
LigandCharge
Software	ABINIT-MP - Open Ver. 1 Rev. 23Q2 / 20200603(SMP)

Total energy (hartree)

FMO2-HF: Electronic energy	-7636954.510147
FMO2-HF: Nuclear repulsion	7467750.175285
FMO2-HF: Total energy	-169204.334862
FMO2-MP2: Total energy	-169682.103501

3D Structure

Snapshot

Ligand structure

V6D

Ligand Interaction

Ligand binding energy (frag 399-400 : frag 1-398)

IFIE [kcal/mol]	PIEDA [kcal/mol]				Charge transfer value [e]
IFIE SUMIFIE SUM at MP2 level.	ESElectro static interaction energy.	EXExchange-repulsion energy.	CT+mixCharge transfer and mixing terms energy.	DI(MP2)Dispersion energy.	q(I=>J)Charge transfer value from I to J fragments.
-296.560106	-245.216558	47.779881	-22.499448	-76.623981	0.094225

Interactive mode: IFIE and PIEDA for fragment #399(:389:V6D)

Summations of interaction energy for fragment #399(:389:V6D)

IFIE [kcal/mol]	PIEDA [kcal/mol]				Charge transfer value [e]
IFIE SUMIFIE SUM at MP2 level.	ESElectro static interaction energy.	EXExchange-repulsion energy.	CT+mixCharge transfer and mixing terms energy.	DI(MP2)Dispersion energy.	q(I=>J)Charge transfer value from I to J fragments.
-61.284	-21.729	31.773	-16.99	-54.339	-0.072

Interaction energy analysis for fragmet #399(:389:V6D)

Snapshot

IFIE Diagram

Base fragment(s) of PIEDA/IFIE

Single fragment	Multi fragments
	Fragment list

Charge [e] FCHARGE : 0 / q_Mulliken : -0.096 / q_NPA : -0.030

Distance from base fragment(s) [Å]

Dist

Interaction energy by IFIE and PIEDA
[kcal/mol]

| Total | > | ES | > | EX | >
| CT+mix | > | DI(MP2) | >

Fragment charge [e]

FCHARGE q_Mulliken
q_NPA q(I=>J)

Residue

Res # RES

Sort

Graph Options

X Axis Label
Y Axis Max Y Axis Min
Display ES EX CT+mix DI(MP2)

frag_NumFragment number.	Res #Residue number.	RES3-letter code of amino acid residue, ligand and solvent molecule.	FCHARGEFormal charge [e].	q_MullikenFragment charge evaluated by Mulliken charge [e].	q_NPAFragment charge evaluated by natural population analysis(NPA) charge [e].	DISTDistance from Ligand [Å].	TotalIFIE at MP2 level [kcal/mol].	ESElectro static interaction energy by PIEDA [kcal/mol].	EXExchange-repulsion energy by PIEDA [kcal/mol].	CT+mixCharge transfer and mixing terms energy by PIEDA [kcal/mol].	DI(MP2)Dispersion energy by PIEDA [kcal/mol].	q(I=>J)Charge transfer value from I to J fragmens [e].
131	131	PRO	0	0.036	0.006	3.240	-0.790	0.024	0.060	-0.173	-0.701	0.000
132	132	GLY	0	0.042	0.034	2.442	-2.348	0.307	4.422	-3.343	-3.734	-0.003
133	133	ARG	1	0.817	0.876	2.544	-0.551	-1.747	1.154	2.327	-2.285	-0.018
134	134	VAL	0	0.035	0.008	5.067	-0.466	-0.310	-0.001	-0.011	-0.144	0.000
135	135	PHE	0	0.035	0.011	2.595	-12.260	-4.865	7.296	-3.655	-11.036	0.014
136	136	ASP	-1	-0.765	-0.837	2.491	-7.355	-4.152	1.363	-1.852	-2.714	-0.003
137	137	MET	0	-0.040	-0.011	3.110	1.073	0.735	0.056	0.692	-0.410	0.000
139	139	ASN	0	-0.107	-0.062	2.712	-0.631	0.604	1.175	-0.575	-1.834	-0.003
140	140	ARG	1	0.764	0.863	4.740	1.518	1.648	-0.001	-0.008	-0.121	0.000
167	167	GLN	0	-0.011	-0.003	2.511	-9.930	-4.538	5.531	-2.959	-7.964	0.004
168	168	ILE	0	0.009	-0.002	3.502	-1.997	-1.687	0.080	0.745	-1.136	-0.001
170	170	ASP	-1	-0.849	-0.914	2.544	-11.283	-6.137	1.377	-2.990	-3.533	-0.036
171	171	ILE	0	-0.072	-0.042	3.470	-0.326	0.714	0.232	-0.175	-1.096	0.000
391	385	A	-1	-0.460	-0.572	2.705	-3.536	-1.281	0.644	-0.982	-1.917	-0.006
392	385	A	0	-0.303	-0.287	3.328	-2.450	-0.885	0.111	-0.670	-1.007	-0.006
393	386	G	-1	-0.568	-0.671	2.647	-1.014	-0.001	0.515	-0.422	-1.106	0.003
394	386	G	0	-0.358	-0.311	2.928	-8.759	-0.426	7.753	-2.872	-13.214	-0.017
398	388	G	0	-0.317	-0.267	3.916	-1.472	-1.025	0.006	-0.067	-0.387	0.000
1	1	GLU	0	-0.119	-0.072	33.562	0.004	0.004	0.000	0.000	0.000	0.000
2	2	ILE	0	0.069	0.033	35.267	0.000	0.000	0.000	0.000	0.000	0.000
3	3	VAL	0	-0.003	-0.004	35.602	-0.001	-0.001	0.000	0.000	0.000	0.000
4	4	ASP	-1	-0.838	-0.913	35.636	-0.006	-0.006	0.000	0.000	0.000	0.000
5	5	SER	0	0.072	0.029	37.438	-0.003	-0.003	0.000	0.000	0.000	0.000
6	6	PHE	0	0.000	-0.016	31.189	0.001	0.001	0.000	0.000	0.000	0.000
7	7	ASP	-1	-0.917	-0.959	35.445	-0.011	-0.011	0.000	0.000	0.000	0.000
8	8	ASP	-1	-0.880	-0.930	38.747	-0.005	-0.005	0.000	0.000	0.000	0.000
9	9	MET	0	-0.178	-0.091	31.957	0.001	0.001	0.000	0.000	0.000	0.000
10	10	ASN	0	-0.052	-0.013	35.440	0.001	0.001	0.000	0.000	0.000	0.000
11	11	LEU	0	-0.013	-0.003	30.822	0.000	0.000	0.000	0.000	0.000	0.000
12	12	SER	0	0.044	0.021	32.604	0.000	0.000	0.000	0.000	0.000	0.000
13	13	GLU	-1	-0.845	-0.934	34.521	-0.019	-0.019	0.000	0.000	0.000	0.000
14	14	SER	0	-0.076	-0.042	33.535	-0.001	-0.001	0.000	0.000	0.000	0.000
15	15	LEU	0	0.036	0.024	28.788	-0.003	-0.003	0.000	0.000	0.000	0.000
16	16	LEU	0	0.008	0.008	32.346	-0.001	-0.001	0.000	0.000	0.000	0.000
17	17	ARG	1	0.915	0.948	35.101	0.026	0.026	0.000	0.000	0.000	0.000
18	18	GLY	0	0.044	0.032	32.457	-0.001	-0.001	0.000	0.000	0.000	0.000
19	19	ILE	0	-0.011	-0.014	30.708	-0.002	-0.002	0.000	0.000	0.000	0.000
20	20	TYR	0	-0.025	-0.025	32.803	0.000	0.000	0.000	0.000	0.000	0.000
21	21	ALA	0	-0.027	-0.017	34.929	0.000	0.000	0.000	0.000	0.000	0.000
22	22	TYR	0	-0.042	-0.012	26.891	-0.002	-0.002	0.000	0.000	0.000	0.000
23	23	GLY	0	-0.019	0.004	32.895	-0.001	-0.001	0.000	0.000	0.000	0.000
24	24	PHE	0	-0.075	-0.043	28.490	0.000	0.000	0.000	0.000	0.000	0.000
25	25	GLU	-1	-0.865	-0.923	33.223	-0.016	-0.016	0.000	0.000	0.000	0.000
26	26	LYS	1	0.831	0.903	33.713	0.009	0.009	0.000	0.000	0.000	0.000
27	27	PRO	0	-0.030	-0.003	32.140	0.000	0.000	0.000	0.000	0.000	0.000
28	28	SER	0	0.051	0.031	30.745	0.002	0.002	0.000	0.000	0.000	0.000
29	29	ALA	0	0.036	0.003	32.305	0.001	0.001	0.000	0.000	0.000	0.000
30	30	ILE	0	-0.013	0.000	26.640	0.002	0.002	0.000	0.000	0.000	0.000
31	31	GLN	0	0.021	-0.011	26.981	0.004	0.004	0.000	0.000	0.000	0.000
32	32	GLN	0	-0.034	-0.026	29.654	0.002	0.002	0.000	0.000	0.000	0.000
33	33	ARG	1	0.937	0.969	31.122	-0.018	-0.018	0.000	0.000	0.000	0.000
34	34	ALA	0	0.001	0.006	26.185	0.003	0.003	0.000	0.000	0.000	0.000
35	35	ILE	0	0.063	0.035	26.843	0.001	0.001	0.000	0.000	0.000	0.000
36	36	LEU	0	0.048	0.024	27.839	0.001	0.001	0.000	0.000	0.000	0.000
37	37	PRO	0	-0.031	-0.022	26.741	0.001	0.001	0.000	0.000	0.000	0.000
38	38	CYS	0	-0.019	-0.013	23.842	0.003	0.003	0.000	0.000	0.000	0.000
39	39	ILE	0	0.009	0.011	24.682	-0.001	-0.001	0.000	0.000	0.000	0.000
40	40	LYS	1	0.912	0.967	27.308	-0.015	-0.015	0.000	0.000	0.000	0.000
41	41	GLY	0	0.072	0.047	23.549	0.002	0.002	0.000	0.000	0.000	0.000
42	42	TYR	0	-0.045	-0.025	22.590	0.004	0.004	0.000	0.000	0.000	0.000
43	43	ASP	-1	-0.714	-0.826	18.254	0.048	0.048	0.000	0.000	0.000	0.000
44	44	VAL	0	-0.029	-0.020	20.136	-0.001	-0.001	0.000	0.000	0.000	0.000
45	45	ILE	0	0.000	0.009	19.453	0.003	0.003	0.000	0.000	0.000	0.000
46	46	ALA	0	0.022	0.001	21.742	-0.003	-0.003	0.000	0.000	0.000	0.000
47	47	GLN	0	-0.003	-0.004	22.959	0.001	0.001	0.000	0.000	0.000	0.000
48	48	ALA	0	-0.007	-0.006	24.101	-0.003	-0.003	0.000	0.000	0.000	0.000
49	49	GLN	0	0.027	0.003	24.533	-0.003	-0.003	0.000	0.000	0.000	0.000
50	50	SER	0	0.014	0.011	25.817	-0.004	-0.004	0.000	0.000	0.000	0.000
51	51	GLY	0	0.050	0.026	26.615	0.001	0.001	0.000	0.000	0.000	0.000
52	52	THR	0	-0.034	-0.022	27.302	0.000	0.000	0.000	0.000	0.000	0.000
53	53	GLY	0	0.042	0.030	26.286	0.000	0.000	0.000	0.000	0.000	0.000
54	54	LYS	1	0.807	0.891	18.990	0.018	0.018	0.000	0.000	0.000	0.000
55	55	THR	0	0.027	-0.002	19.818	-0.001	-0.001	0.000	0.000	0.000	0.000
56	56	ALA	0	0.059	0.031	21.741	-0.001	-0.001	0.000	0.000	0.000	0.000
57	57	THR	0	-0.007	-0.009	24.086	0.003	0.003	0.000	0.000	0.000	0.000
58	58	PHE	0	0.034	0.024	17.939	0.003	0.003	0.000	0.000	0.000	0.000
59	59	ALA	0	0.007	0.014	22.068	-0.001	-0.001	0.000	0.000	0.000	0.000
60	60	ILE	0	0.016	0.008	23.117	-0.001	-0.001	0.000	0.000	0.000	0.000
61	61	SER	0	-0.028	-0.035	23.082	0.003	0.003	0.000	0.000	0.000	0.000
62	62	ILE	0	-0.022	-0.010	18.596	0.003	0.003	0.000	0.000	0.000	0.000
63	63	LEU	0	0.000	-0.010	22.865	0.000	0.000	0.000	0.000	0.000	0.000
64	64	GLN	0	0.027	0.024	25.793	-0.003	-0.003	0.000	0.000	0.000	0.000
65	65	GLN	0	-0.096	-0.061	24.064	0.004	0.004	0.000	0.000	0.000	0.000
66	66	ILE	0	-0.093	-0.033	21.716	-0.001	-0.001	0.000	0.000	0.000	0.000
67	67	GLU	-1	-0.905	-0.942	25.556	-0.025	-0.025	0.000	0.000	0.000	0.000
68	68	LEU	0	0.019	-0.010	26.655	-0.006	-0.006	0.000	0.000	0.000	0.000
69	69	ASP	-1	-0.907	-0.952	28.427	-0.044	-0.044	0.000	0.000	0.000	0.000
70	70	LEU	0	-0.090	-0.027	22.856	-0.003	-0.003	0.000	0.000	0.000	0.000
71	71	LYS	1	0.953	0.974	24.136	0.068	0.068	0.000	0.000	0.000	0.000
72	72	ALA	0	-0.020	-0.024	19.518	-0.009	-0.009	0.000	0.000	0.000	0.000
73	73	THR	0	0.007	0.003	15.790	-0.001	-0.001	0.000	0.000	0.000	0.000
74	74	GLN	0	-0.051	-0.037	18.043	0.013	0.013	0.000	0.000	0.000	0.000
75	75	ALA	0	-0.013	-0.003	17.614	0.015	0.015	0.000	0.000	0.000	0.000
76	76	LEU	0	-0.018	0.000	10.037	-0.021	-0.021	0.000	0.000	0.000	0.000
77	77	VAL	0	-0.002	0.005	13.767	0.020	0.020	0.000	0.000	0.000	0.000
78	78	LEU	0	-0.016	-0.009	7.106	-0.011	-0.011	0.000	0.000	0.000	0.000
79	79	ALA	0	0.028	0.008	10.089	0.003	0.003	0.000	0.000	0.000	0.000
80	80	PRO	0	0.040	0.014	8.945	-0.037	-0.037	0.000	0.000	0.000	0.000
81	81	THR	0	-0.005	-0.015	8.784	-0.117	-0.117	0.000	0.000	0.000	0.000
82	82	ARG	1	0.887	0.913	7.668	0.868	0.868	0.000	0.000	0.000	0.000
83	83	GLU	-1	-0.774	-0.859	11.651	-0.249	-0.249	0.000	0.000	0.000	0.000
84	84	LEU	0	0.018	0.013	13.833	0.023	0.023	0.000	0.000	0.000	0.000
85	85	ALA	0	0.020	0.007	11.795	0.023	0.023	0.000	0.000	0.000	0.000
86	86	GLN	0	-0.030	-0.033	13.967	0.022	0.022	0.000	0.000	0.000	0.000
87	87	GLN	0	0.015	0.028	16.788	0.018	0.018	0.000	0.000	0.000	0.000
88	88	ILE	0	0.023	0.015	15.310	0.010	0.010	0.000	0.000	0.000	0.000
89	89	GLN	0	0.025	0.001	17.392	0.009	0.009	0.000	0.000	0.000	0.000
90	90	LYS	1	0.828	0.901	19.138	0.141	0.141	0.000	0.000	0.000	0.000
91	91	VAL	0	0.007	0.012	22.088	0.006	0.006	0.000	0.000	0.000	0.000
92	92	VAL	0	0.001	-0.008	19.743	0.006	0.006	0.000	0.000	0.000	0.000
93	93	MET	0	-0.027	-0.005	22.586	0.001	0.001	0.000	0.000	0.000	0.000
94	94	ALA	0	0.009	0.013	24.884	0.004	0.004	0.000	0.000	0.000	0.000
95	95	LEU	0	-0.025	-0.013	25.818	0.004	0.004	0.000	0.000	0.000	0.000
96	96	GLY	0	0.004	-0.001	26.959	0.004	0.004	0.000	0.000	0.000	0.000
97	97	ASP	-1	-0.935	-0.962	28.060	-0.063	-0.063	0.000	0.000	0.000	0.000
98	98	TYR	0	-0.030	-0.005	30.521	0.003	0.003	0.000	0.000	0.000	0.000
99	99	MET	0	-0.058	-0.039	29.512	0.001	0.001	0.000	0.000	0.000	0.000
100	100	GLY	0	0.020	0.031	30.395	0.001	0.001	0.000	0.000	0.000	0.000
101	101	ALA	0	-0.053	-0.017	25.695	-0.004	-0.004	0.000	0.000	0.000	0.000
102	102	SER	0	0.002	0.004	23.276	-0.005	-0.005	0.000	0.000	0.000	0.000
103	103	CYS	0	-0.051	-0.044	18.783	-0.001	-0.001	0.000	0.000	0.000	0.000
104	104	HIS	0	-0.020	-0.024	14.120	0.024	0.024	0.000	0.000	0.000	0.000
105	105	ALA	0	0.008	0.002	14.146	0.009	0.009	0.000	0.000	0.000	0.000
106	106	CYS	0	-0.047	-0.001	9.451	-0.019	-0.019	0.000	0.000	0.000	0.000
107	107	ILE	0	0.015	0.004	9.417	0.025	0.025	0.000	0.000	0.000	0.000
108	108	GLY	0	0.018	0.023	7.835	-0.001	-0.001	0.000	0.000	0.000	0.000
109	109	GLY	0	0.017	0.006	8.417	0.031	0.031	0.000	0.000	0.000	0.000
110	110	THR	0	-0.032	-0.023	10.874	0.069	0.069	0.000	0.000	0.000	0.000
111	111	ASN	0	0.008	-0.003	11.444	-0.071	-0.071	0.000	0.000	0.000	0.000
112	112	VAL	0	0.100	0.044	8.398	0.029	0.029	0.000	0.000	0.000	0.000
113	113	ARG	1	0.835	0.905	11.613	0.392	0.392	0.000	0.000	0.000	0.000
114	114	ALA	0	-0.020	-0.008	14.498	0.033	0.033	0.000	0.000	0.000	0.000
115	115	GLU	-1	-0.759	-0.862	10.799	-0.375	-0.375	0.000	0.000	0.000	0.000
116	116	VAL	0	0.003	0.000	12.581	0.029	0.029	0.000	0.000	0.000	0.000
117	117	GLN	0	-0.011	-0.017	14.946	0.035	0.035	0.000	0.000	0.000	0.000
118	118	LYS	1	0.946	0.986	17.281	0.214	0.214	0.000	0.000	0.000	0.000
119	119	LEU	0	-0.007	-0.007	11.363	0.009	0.009	0.000	0.000	0.000	0.000
120	120	GLN	0	-0.024	-0.013	13.715	-0.015	-0.015	0.000	0.000	0.000	0.000
121	121	MET	0	-0.076	-0.040	16.393	0.026	0.026	0.000	0.000	0.000	0.000
122	122	GLU	-1	-0.908	-0.954	19.849	-0.113	-0.113	0.000	0.000	0.000	0.000
123	123	ALA	0	-0.083	-0.019	19.634	0.013	0.013	0.000	0.000	0.000	0.000
124	124	PRO	0	0.010	0.026	17.740	0.014	0.014	0.000	0.000	0.000	0.000
125	125	HIS	0	0.103	0.052	19.396	-0.011	-0.011	0.000	0.000	0.000	0.000
126	126	ILE	0	-0.013	-0.006	18.065	0.009	0.009	0.000	0.000	0.000	0.000
127	127	ILE	0	0.007	0.008	12.579	-0.018	-0.018	0.000	0.000	0.000	0.000
128	128	VAL	0	0.010	0.001	13.427	0.025	0.025	0.000	0.000	0.000	0.000
129	129	GLY	0	0.033	-0.002	10.093	-0.041	-0.041	0.000	0.000	0.000	0.000
130	130	THR	0	-0.022	-0.020	6.242	0.092	0.092	0.000	0.000	0.000	0.000
138	138	LEU	0	0.015	0.017	6.037	0.131	0.131	0.000	0.000	0.000	0.000
141	141	ARG	1	0.895	0.942	6.308	0.488	0.488	0.000	0.000	0.000	0.000
142	142	TYR	0	-0.001	-0.001	8.805	0.073	0.073	0.000	0.000	0.000	0.000
143	143	LEU	0	0.066	0.041	9.681	0.070	0.070	0.000	0.000	0.000	0.000
144	144	SER	0	-0.027	-0.019	10.393	0.002	0.002	0.000	0.000	0.000	0.000
145	145	PRO	0	0.070	0.019	10.815	0.007	0.007	0.000	0.000	0.000	0.000
146	146	LYS	1	0.877	0.934	13.045	0.022	0.022	0.000	0.000	0.000	0.000
147	147	TYR	0	0.030	0.014	16.459	0.012	0.012	0.000	0.000	0.000	0.000
148	148	ILE	0	-0.030	0.010	13.362	0.001	0.001	0.000	0.000	0.000	0.000
149	149	LYS	1	0.961	0.988	17.204	0.025	0.025	0.000	0.000	0.000	0.000
150	150	MET	0	-0.031	0.006	17.477	0.008	0.008	0.000	0.000	0.000	0.000
151	151	PHE	0	0.020	-0.004	8.567	-0.020	-0.020	0.000	0.000	0.000	0.000
152	152	VAL	0	0.006	0.002	14.518	0.011	0.011	0.000	0.000	0.000	0.000
153	153	LEU	0	0.007	0.003	10.401	0.007	0.007	0.000	0.000	0.000	0.000
154	154	ASP	-1	-0.782	-0.889	13.652	-0.027	-0.027	0.000	0.000	0.000	0.000
155	155	GLU	-1	-0.834	-0.915	13.718	-0.011	-0.011	0.000	0.000	0.000	0.000
156	156	ALA	0	-0.004	-0.008	14.119	0.021	0.021	0.000	0.000	0.000	0.000
157	157	ASP	-1	-0.787	-0.846	14.166	0.073	0.073	0.000	0.000	0.000	0.000
158	158	GLU	-1	-0.877	-0.933	11.342	0.040	0.040	0.000	0.000	0.000	0.000
159	159	MET	0	-0.060	-0.006	7.498	0.044	0.044	0.000	0.000	0.000	0.000
160	160	LEU	0	-0.007	-0.012	10.026	0.102	0.102	0.000	0.000	0.000	0.000
161	161	SER	0	0.014	0.003	11.359	-0.027	-0.027	0.000	0.000	0.000	0.000
162	162	ARG	1	0.783	0.838	10.440	-0.082	-0.082	0.000	0.000	0.000	0.000
163	163	GLY	0	0.061	0.038	7.841	0.012	0.012	0.000	0.000	0.000	0.000
164	164	PHE	0	-0.021	-0.003	5.361	0.475	0.475	0.000	0.000	0.000	0.000
165	165	LYS	1	0.796	0.903	6.941	0.084	0.084	0.000	0.000	0.000	0.000
166	166	ASP	-1	-0.835	-0.911	4.914	-0.051	-0.051	0.000	0.000	0.000	0.000
169	169	TYR	0	0.025	0.011	6.312	-0.243	-0.243	0.000	0.000	0.000	0.000
172	172	PHE	0	-0.030	-0.023	5.508	0.234	0.234	0.000	0.000	0.000	0.000
173	173	GLN	0	-0.029	-0.020	7.526	0.268	0.268	0.000	0.000	0.000	0.000
174	174	LYS	1	0.863	0.960	6.117	-0.193	-0.193	0.000	0.000	0.000	0.000
175	175	LEU	0	-0.035	-0.011	8.982	-0.046	-0.046	0.000	0.000	0.000	0.000
176	176	ASN	0	0.016	0.009	11.679	0.056	0.056	0.000	0.000	0.000	0.000
177	177	SER	0	0.062	0.043	15.003	-0.018	-0.018	0.000	0.000	0.000	0.000
178	178	ASN	0	-0.062	-0.040	16.261	-0.001	-0.001	0.000	0.000	0.000	0.000
179	179	THR	0	-0.072	-0.044	13.882	-0.016	-0.016	0.000	0.000	0.000	0.000
180	180	GLN	0	-0.046	-0.025	16.449	0.001	0.001	0.000	0.000	0.000	0.000
181	181	VAL	0	-0.004	-0.009	13.692	-0.005	-0.005	0.000	0.000	0.000	0.000
182	182	VAL	0	-0.025	-0.012	16.184	-0.001	-0.001	0.000	0.000	0.000	0.000
183	183	LEU	0	0.016	0.007	14.980	0.004	0.004	0.000	0.000	0.000	0.000
184	184	LEU	0	-0.010	-0.008	17.639	-0.008	-0.008	0.000	0.000	0.000	0.000
185	185	SER	0	-0.023	-0.038	18.048	-0.003	-0.003	0.000	0.000	0.000	0.000
186	186	ALA	0	0.050	0.042	20.178	0.001	0.001	0.000	0.000	0.000	0.000
187	187	THR	0	-0.014	-0.011	19.754	-0.003	-0.003	0.000	0.000	0.000	0.000
188	188	MET	0	-0.017	-0.022	18.233	0.008	0.008	0.000	0.000	0.000	0.000
189	189	PRO	0	0.062	0.035	18.795	-0.002	-0.002	0.000	0.000	0.000	0.000
190	190	SER	0	0.015	0.004	20.829	0.003	0.003	0.000	0.000	0.000	0.000
191	191	ASP	-1	-0.859	-0.933	17.583	0.083	0.083	0.000	0.000	0.000	0.000
192	192	VAL	0	-0.006	0.004	15.696	0.007	0.007	0.000	0.000	0.000	0.000
193	193	LEU	0	-0.007	-0.006	17.436	-0.001	-0.001	0.000	0.000	0.000	0.000
194	194	GLU	-1	-0.845	-0.899	19.016	0.063	0.063	0.000	0.000	0.000	0.000
195	195	VAL	0	-0.054	-0.030	12.470	-0.004	-0.004	0.000	0.000	0.000	0.000
196	196	THR	0	0.001	-0.030	14.640	-0.008	-0.008	0.000	0.000	0.000	0.000
197	197	LYS	1	0.786	0.889	16.095	-0.070	-0.070	0.000	0.000	0.000	0.000
198	198	LYS	1	0.897	0.949	13.585	-0.082	-0.082	0.000	0.000	0.000	0.000
199	199	PHE	0	-0.023	-0.005	11.499	-0.001	-0.001	0.000	0.000	0.000	0.000
200	200	MET	0	-0.016	0.018	15.193	0.004	0.004	0.000	0.000	0.000	0.000
201	201	ARG	1	0.836	0.887	17.188	-0.046	-0.046	0.000	0.000	0.000	0.000
202	202	ASP	-1	-0.981	-0.986	20.507	0.046	0.046	0.000	0.000	0.000	0.000
203	203	PRO	0	-0.029	0.010	19.737	-0.004	-0.004	0.000	0.000	0.000	0.000
204	204	ILE	0	0.015	-0.001	22.369	-0.001	-0.001	0.000	0.000	0.000	0.000
205	205	ARG	1	0.962	0.976	22.212	-0.051	-0.051	0.000	0.000	0.000	0.000
206	206	ILE	0	-0.067	-0.028	25.703	-0.003	-0.003	0.000	0.000	0.000	0.000
207	207	LEU	0	0.002	-0.001	24.388	0.000	0.000	0.000	0.000	0.000	0.000
208	208	VAL	0	0.007	0.000	27.763	-0.003	-0.003	0.000	0.000	0.000	0.000
209	209	LYS	1	0.908	0.968	28.857	-0.011	-0.011	0.000	0.000	0.000	0.000
210	210	LYS	1	0.981	0.979	26.968	-0.033	-0.033	0.000	0.000	0.000	0.000
211	211	GLU	-1	-0.872	-0.935	30.085	0.009	0.009	0.000	0.000	0.000	0.000
212	212	GLU	-1	-0.923	-0.966	32.571	0.004	0.004	0.000	0.000	0.000	0.000
213	213	LEU	0	-0.093	-0.036	26.119	-0.001	-0.001	0.000	0.000	0.000	0.000
214	214	THR	0	-0.026	-0.011	29.494	-0.004	-0.004	0.000	0.000	0.000	0.000
215	215	LEU	0	0.034	0.021	27.359	-0.001	-0.001	0.000	0.000	0.000	0.000
216	216	GLU	-1	-0.878	-0.936	31.741	-0.012	-0.012	0.000	0.000	0.000	0.000
217	217	GLY	0	-0.064	-0.028	34.151	-0.001	-0.001	0.000	0.000	0.000	0.000
218	218	ILE	0	-0.047	-0.024	30.426	-0.002	-0.002	0.000	0.000	0.000	0.000
219	219	ARG	1	0.948	0.984	33.916	0.018	0.018	0.000	0.000	0.000	0.000
220	220	GLN	0	0.043	0.017	31.354	-0.001	-0.001	0.000	0.000	0.000	0.000
221	221	PHE	0	0.040	0.017	34.345	0.001	0.001	0.000	0.000	0.000	0.000
222	222	TYR	0	-0.050	-0.024	34.224	-0.001	-0.001	0.000	0.000	0.000	0.000
223	223	ILE	0	0.072	0.034	35.528	0.000	0.000	0.000	0.000	0.000	0.000
224	224	ASN	0	-0.007	0.000	36.090	0.001	0.001	0.000	0.000	0.000	0.000
225	225	VAL	0	0.029	0.006	34.446	-0.001	-0.001	0.000	0.000	0.000	0.000
226	226	GLU	-1	-0.861	-0.892	37.774	-0.002	-0.002	0.000	0.000	0.000	0.000
227	227	ARG	1	0.848	0.887	35.907	0.006	0.006	0.000	0.000	0.000	0.000
228	228	GLU	-1	-0.747	-0.872	29.471	-0.018	-0.018	0.000	0.000	0.000	0.000
229	229	GLU	-1	-0.979	-0.997	33.104	-0.017	-0.017	0.000	0.000	0.000	0.000
230	230	TRP	0	0.028	0.024	35.499	-0.001	-0.001	0.000	0.000	0.000	0.000
231	231	LYS	1	0.824	0.920	28.520	0.013	0.013	0.000	0.000	0.000	0.000
232	232	LEU	0	0.006	0.001	32.699	-0.002	-0.002	0.000	0.000	0.000	0.000
233	233	ASP	-1	-0.790	-0.900	34.553	-0.021	-0.021	0.000	0.000	0.000	0.000
234	234	THR	0	0.003	0.004	36.008	0.001	0.001	0.000	0.000	0.000	0.000
235	235	LEU	0	-0.040	-0.034	31.531	-0.001	-0.001	0.000	0.000	0.000	0.000
236	236	CYS	0	-0.072	-0.041	35.520	-0.003	-0.003	0.000	0.000	0.000	0.000
237	237	ASP	-1	-0.890	-0.927	38.499	-0.018	-0.018	0.000	0.000	0.000	0.000
238	238	LEU	0	-0.040	-0.022	34.956	0.000	0.000	0.000	0.000	0.000	0.000
239	239	TYR	0	0.020	0.017	34.206	-0.003	-0.003	0.000	0.000	0.000	0.000
240	240	GLU	-1	-0.882	-0.926	37.970	-0.024	-0.024	0.000	0.000	0.000	0.000
241	241	THR	0	0.002	-0.027	37.048	-0.002	-0.002	0.000	0.000	0.000	0.000
242	242	LEU	0	-0.010	-0.007	32.139	-0.002	-0.002	0.000	0.000	0.000	0.000
243	243	THR	0	-0.098	-0.048	35.856	-0.003	-0.003	0.000	0.000	0.000	0.000
244	244	ILE	0	-0.042	-0.010	38.883	-0.001	-0.001	0.000	0.000	0.000	0.000
245	245	THR	0	-0.084	-0.043	34.735	-0.001	-0.001	0.000	0.000	0.000	0.000
246	246	GLN	0	-0.047	-0.024	28.729	0.003	0.003	0.000	0.000	0.000	0.000
247	247	ALA	0	0.006	-0.008	30.482	0.003	0.003	0.000	0.000	0.000	0.000
248	248	VAL	0	-0.019	-0.009	23.836	-0.006	-0.006	0.000	0.000	0.000	0.000
249	249	ILE	0	-0.003	0.000	26.312	0.007	0.007	0.000	0.000	0.000	0.000
250	250	PHE	0	0.025	0.004	20.000	-0.007	-0.007	0.000	0.000	0.000	0.000
251	251	ILE	0	-0.050	-0.021	21.831	0.009	0.009	0.000	0.000	0.000	0.000
252	252	ASN	0	0.040	0.001	20.337	-0.010	-0.010	0.000	0.000	0.000	0.000
253	253	THR	0	-0.053	-0.016	18.688	0.003	0.003	0.000	0.000	0.000	0.000
254	254	ARG	1	0.963	0.950	12.597	0.175	0.175	0.000	0.000	0.000	0.000
255	255	ARG	1	0.972	0.996	18.599	0.018	0.018	0.000	0.000	0.000	0.000
256	256	LYS	1	0.754	0.835	21.371	0.021	0.021	0.000	0.000	0.000	0.000
257	257	VAL	0	0.046	0.025	20.362	0.003	0.003	0.000	0.000	0.000	0.000
258	258	ASP	-1	-0.822	-0.890	20.723	-0.108	-0.108	0.000	0.000	0.000	0.000
259	259	TRP	0	-0.031	-0.008	23.620	0.005	0.005	0.000	0.000	0.000	0.000
260	260	LEU	0	-0.017	-0.022	26.395	0.003	0.003	0.000	0.000	0.000	0.000
261	261	THR	0	-0.008	-0.026	25.130	0.000	0.000	0.000	0.000	0.000	0.000
262	262	GLU	-1	-0.909	-0.950	27.730	-0.051	-0.051	0.000	0.000	0.000	0.000
263	263	LYS	1	0.863	0.947	30.442	0.035	0.035	0.000	0.000	0.000	0.000
264	264	MET	0	-0.020	-0.006	30.593	0.004	0.004	0.000	0.000	0.000	0.000
265	265	HIS	0	0.007	-0.002	29.691	0.003	0.003	0.000	0.000	0.000	0.000
266	266	ALA	0	-0.040	-0.016	33.695	0.002	0.002	0.000	0.000	0.000	0.000
267	267	ARG	1	0.761	0.869	35.932	0.028	0.028	0.000	0.000	0.000	0.000
268	268	ASP	-1	-0.896	-0.935	37.537	-0.034	-0.034	0.000	0.000	0.000	0.000
269	269	PHE	0	-0.034	-0.013	34.462	-0.001	-0.001	0.000	0.000	0.000	0.000
270	270	THR	0	-0.016	-0.008	32.241	-0.002	-0.002	0.000	0.000	0.000	0.000
271	271	VAL	0	-0.064	-0.034	28.797	-0.003	-0.003	0.000	0.000	0.000	0.000
272	272	SER	0	0.031	0.018	26.120	-0.006	-0.006	0.000	0.000	0.000	0.000
273	273	ALA	0	0.032	0.010	23.447	0.006	0.006	0.000	0.000	0.000	0.000
274	274	MET	0	-0.007	-0.002	16.878	-0.013	-0.013	0.000	0.000	0.000	0.000
275	275	HIS	0	0.013	-0.017	16.523	-0.016	-0.016	0.000	0.000	0.000	0.000
276	276	GLY	0	0.001	-0.031	12.533	-0.016	-0.016	0.000	0.000	0.000	0.000
277	277	ASP	-1	-1.044	-1.012	12.581	-0.281	-0.281	0.000	0.000	0.000	0.000
278	278	MET	0	-0.004	0.037	15.177	0.033	0.033	0.000	0.000	0.000	0.000
279	279	ASP	-1	-0.847	-0.940	15.533	-0.287	-0.287	0.000	0.000	0.000	0.000
280	280	GLN	0	-0.038	-0.021	13.070	-0.046	-0.046	0.000	0.000	0.000	0.000
281	281	LYS	1	0.890	0.932	15.779	0.265	0.265	0.000	0.000	0.000	0.000
282	282	GLU	-1	-0.889	-0.941	19.230	-0.129	-0.129	0.000	0.000	0.000	0.000
283	283	ARG	1	0.785	0.839	11.450	0.425	0.425	0.000	0.000	0.000	0.000
284	284	ASP	-1	-0.886	-0.924	18.579	-0.155	-0.155	0.000	0.000	0.000	0.000
285	285	VAL	0	-0.003	0.004	20.040	0.014	0.014	0.000	0.000	0.000	0.000
286	286	ILE	0	0.038	0.023	21.832	0.012	0.012	0.000	0.000	0.000	0.000
287	287	MET	0	0.009	0.007	20.218	0.011	0.011	0.000	0.000	0.000	0.000
288	288	ARG	1	0.837	0.907	22.493	0.149	0.149	0.000	0.000	0.000	0.000
289	289	GLU	-1	-0.892	-0.937	24.968	-0.080	-0.080	0.000	0.000	0.000	0.000
290	290	PHE	0	0.003	0.020	25.436	0.008	0.008	0.000	0.000	0.000	0.000
291	291	ARG	1	0.856	0.918	23.110	0.102	0.102	0.000	0.000	0.000	0.000
292	292	SER	0	-0.102	-0.067	27.341	0.006	0.006	0.000	0.000	0.000	0.000
293	293	GLY	0	-0.004	0.005	30.223	0.004	0.004	0.000	0.000	0.000	0.000
294	294	SER	0	-0.035	0.005	30.817	0.005	0.005	0.000	0.000	0.000	0.000
295	295	SER	0	0.005	-0.001	28.028	0.003	0.003	0.000	0.000	0.000	0.000
296	296	ARG	1	0.972	0.978	31.234	0.046	0.046	0.000	0.000	0.000	0.000
297	297	VAL	0	0.025	0.004	30.136	0.002	0.002	0.000	0.000	0.000	0.000
298	298	LEU	0	-0.013	-0.005	23.050	-0.004	-0.004	0.000	0.000	0.000	0.000
299	299	ILE	0	0.008	0.015	23.606	0.005	0.005	0.000	0.000	0.000	0.000
300	300	THR	0	-0.015	-0.031	19.449	-0.018	-0.018	0.000	0.000	0.000	0.000
301	301	THR	0	0.044	0.010	15.894	0.017	0.017	0.000	0.000	0.000	0.000
302	302	ASP	-1	-0.799	-0.895	15.943	-0.036	-0.036	0.000	0.000	0.000	0.000
303	303	LEU	0	-0.024	0.019	13.048	0.001	0.001	0.000	0.000	0.000	0.000
304	304	LEU	0	0.008	-0.006	15.325	-0.001	-0.001	0.000	0.000	0.000	0.000
305	305	ALA	0	0.018	0.011	17.614	0.014	0.014	0.000	0.000	0.000	0.000
306	306	ARG	1	0.792	0.864	14.803	-0.004	-0.004	0.000	0.000	0.000	0.000
307	307	GLY	0	0.027	0.009	17.449	-0.016	-0.016	0.000	0.000	0.000	0.000
308	308	ILE	0	-0.027	-0.006	15.914	0.000	0.000	0.000	0.000	0.000	0.000
309	309	ASP	-1	-0.865	-0.923	19.973	-0.056	-0.056	0.000	0.000	0.000	0.000
310	310	VAL	0	-0.004	-0.021	23.198	-0.010	-0.010	0.000	0.000	0.000	0.000
311	311	GLN	0	0.027	-0.003	25.839	0.004	0.004	0.000	0.000	0.000	0.000
312	312	GLN	0	0.043	0.031	29.133	0.001	0.001	0.000	0.000	0.000	0.000
313	313	VAL	0	-0.040	-0.003	27.104	0.003	0.003	0.000	0.000	0.000	0.000
314	314	SER	0	-0.062	-0.040	30.339	0.003	0.003	0.000	0.000	0.000	0.000
315	315	LEU	0	0.017	0.006	32.157	0.003	0.003	0.000	0.000	0.000	0.000
316	316	VAL	0	0.011	0.000	26.617	-0.004	-0.004	0.000	0.000	0.000	0.000
317	317	ILE	0	0.006	0.007	28.620	0.004	0.004	0.000	0.000	0.000	0.000
318	318	ASN	0	-0.001	-0.006	25.458	-0.008	-0.008	0.000	0.000	0.000	0.000
319	319	TYR	0	0.048	0.018	26.995	0.003	0.003	0.000	0.000	0.000	0.000
320	320	ASP	-1	-0.806	-0.880	24.342	-0.019	-0.019	0.000	0.000	0.000	0.000
321	321	LEU	0	0.055	0.028	25.426	-0.003	-0.003	0.000	0.000	0.000	0.000
322	322	PRO	0	-0.018	0.020	21.891	0.003	0.003	0.000	0.000	0.000	0.000
323	323	THR	0	0.049	-0.003	21.662	0.002	0.002	0.000	0.000	0.000	0.000
324	324	ASN	0	-0.001	0.012	17.830	-0.003	-0.003	0.000	0.000	0.000	0.000
325	325	ARG	1	0.966	0.987	20.938	-0.038	-0.038	0.000	0.000	0.000	0.000
326	326	GLU	-1	-0.876	-0.942	20.153	0.040	0.040	0.000	0.000	0.000	0.000
327	327	ASN	0	-0.039	-0.032	17.502	-0.005	-0.005	0.000	0.000	0.000	0.000
328	328	TYR	0	0.018	-0.001	19.960	-0.011	-0.011	0.000	0.000	0.000	0.000
329	329	ILE	0	0.012	0.005	23.174	-0.006	-0.006	0.000	0.000	0.000	0.000
330	330	HIS	0	-0.045	-0.025	19.640	-0.013	-0.013	0.000	0.000	0.000	0.000
331	331	ARG	1	0.803	0.879	20.135	0.020	0.020	0.000	0.000	0.000	0.000
332	332	ILE	0	0.001	0.001	23.069	-0.005	-0.005	0.000	0.000	0.000	0.000
333	333	GLY	0	0.007	0.023	24.854	-0.001	-0.001	0.000	0.000	0.000	0.000
334	334	ARG	1	0.786	0.891	21.214	0.056	0.056	0.000	0.000	0.000	0.000
335	335	GLY	0	0.017	0.008	24.922	-0.004	-0.004	0.000	0.000	0.000	0.000
336	336	GLY	0	0.012	-0.008	28.747	0.001	0.001	0.000	0.000	0.000	0.000
337	337	ARG	1	0.741	0.898	24.923	0.050	0.050	0.000	0.000	0.000	0.000
338	338	PHE	0	-0.038	-0.033	29.718	0.001	0.001	0.000	0.000	0.000	0.000
339	339	GLY	0	0.026	0.020	31.601	0.001	0.001	0.000	0.000	0.000	0.000
340	340	ARG	1	0.849	0.928	33.585	0.036	0.036	0.000	0.000	0.000	0.000
341	341	LYS	1	0.927	0.951	34.289	0.019	0.019	0.000	0.000	0.000	0.000
342	342	GLY	0	0.104	0.055	32.810	-0.001	-0.001	0.000	0.000	0.000	0.000
343	343	VAL	0	-0.050	-0.009	33.151	0.003	0.003	0.000	0.000	0.000	0.000
344	344	ALA	0	0.012	0.008	30.244	-0.003	-0.003	0.000	0.000	0.000	0.000
345	345	ILE	0	0.021	0.013	31.638	0.003	0.003	0.000	0.000	0.000	0.000
346	346	ASN	0	-0.009	-0.011	29.560	-0.003	-0.003	0.000	0.000	0.000	0.000
347	347	MET	0	0.007	0.015	31.059	0.001	0.001	0.000	0.000	0.000	0.000
348	348	VAL	0	-0.030	-0.012	31.627	0.002	0.002	0.000	0.000	0.000	0.000
349	349	THR	0	-0.023	-0.034	32.083	0.001	0.001	0.000	0.000	0.000	0.000
350	350	GLU	-1	-0.853	-0.940	34.684	0.006	0.006	0.000	0.000	0.000	0.000
351	351	GLU	-1	-0.891	-0.928	31.170	0.017	0.017	0.000	0.000	0.000	0.000
352	352	ASP	-1	-0.855	-0.898	29.361	0.002	0.002	0.000	0.000	0.000	0.000
353	353	LYS	1	0.832	0.904	31.572	-0.002	-0.002	0.000	0.000	0.000	0.000
354	354	ARG	1	0.833	0.897	29.732	-0.018	-0.018	0.000	0.000	0.000	0.000
355	355	THR	0	0.050	0.031	26.986	0.003	0.003	0.000	0.000	0.000	0.000
356	356	LEU	0	0.018	0.013	29.895	0.001	0.001	0.000	0.000	0.000	0.000
357	357	ARG	1	0.856	0.920	31.967	-0.007	-0.007	0.000	0.000	0.000	0.000
358	358	ASP	-1	-0.878	-0.917	28.785	0.026	0.026	0.000	0.000	0.000	0.000
359	359	ILE	0	-0.058	-0.028	26.926	0.002	0.002	0.000	0.000	0.000	0.000
360	360	GLU	-1	-0.781	-0.884	29.786	0.005	0.005	0.000	0.000	0.000	0.000
361	361	THR	0	-0.047	-0.037	32.059	0.001	0.001	0.000	0.000	0.000	0.000
362	362	PHE	0	-0.077	-0.039	25.132	0.002	0.002	0.000	0.000	0.000	0.000
363	363	TYR	0	-0.042	-0.052	24.936	0.000	0.000	0.000	0.000	0.000	0.000
364	364	ASN	0	-0.093	-0.032	31.342	-0.001	-0.001	0.000	0.000	0.000	0.000
365	365	THR	0	-0.018	-0.006	34.536	-0.001	-0.001	0.000	0.000	0.000	0.000
366	366	SER	0	-0.047	-0.021	35.231	0.000	0.000	0.000	0.000	0.000	0.000
367	367	ILE	0	-0.022	-0.019	31.884	-0.001	-0.001	0.000	0.000	0.000	0.000
368	368	GLU	-1	-0.947	-0.966	36.402	-0.005	-0.005	0.000	0.000	0.000	0.000
369	369	GLU	-1	-0.950	-0.988	38.605	-0.005	-0.005	0.000	0.000	0.000	0.000
370	370	MET	0	-0.016	0.002	38.570	-0.001	-0.001	0.000	0.000	0.000	0.000
371	371	PRO	0	-0.007	0.006	40.436	0.001	0.001	0.000	0.000	0.000	0.000
372	372	LEU	0	0.016	-0.011	43.288	-0.001	-0.001	0.000	0.000	0.000	0.000
373	373	ASN	0	-0.075	-0.038	45.772	0.000	0.000	0.000	0.000	0.000	0.000
374	374	VAL	0	0.027	0.016	38.963	-0.001	-0.001	0.000	0.000	0.000	0.000
375	375	ALA	0	0.018	-0.005	41.075	-0.001	-0.001	0.000	0.000	0.000	0.000
376	376	ASP	-1	-0.870	-0.926	42.357	-0.019	-0.019	0.000	0.000	0.000	0.000
377	377	LEU	0	-0.139	-0.068	40.779	0.000	0.000	0.000	0.000	0.000	0.000
378	378	ILE	-1	-0.831	-0.868	36.724	-0.029	-0.029	0.000	0.000	0.000	0.000
379	379	A	-1	-0.516	-0.623	11.751	0.188	0.188	0.000	0.000	0.000	0.000
380	379	A	0	-0.352	-0.303	13.987	0.001	0.001	0.000	0.000	0.000	0.000
381	380	G	-1	-0.549	-0.625	15.795	0.137	0.137	0.000	0.000	0.000	0.000
382	380	G	0	-0.363	-0.310	16.945	0.011	0.011	0.000	0.000	0.000	0.000
383	381	A	-1	-0.604	-0.681	17.576	0.050	0.050	0.000	0.000	0.000	0.000
384	381	A	0	-0.384	-0.318	15.296	-0.003	-0.003	0.000	0.000	0.000	0.000
385	382	G	-1	-0.520	-0.647	15.104	-0.047	-0.047	0.000	0.000	0.000	0.000
386	382	G	0	-0.304	-0.266	12.484	0.075	0.075	0.000	0.000	0.000	0.000
387	383	A	-1	-0.448	-0.559	11.079	-0.205	-0.205	0.000	0.000	0.000	0.000
388	383	A	0	-0.349	-0.307	9.242	0.012	0.012	0.000	0.000	0.000	0.000
389	384	G	-1	-0.465	-0.572	7.003	-0.516	-0.516	0.000	0.000	0.000	0.000
390	384	G	0	-0.399	-0.332	5.342	-0.342	-0.342	0.000	0.000	0.000	0.000
395	387	A	-1	-0.537	-0.645	5.747	-0.709	-0.709	0.000	0.000	0.000	0.000
396	387	A	0	-0.332	-0.285	5.978	0.011	0.011	0.000	0.000	0.000	0.000
397	388	G	0	0.284	0.248	8.990	0.040	0.040	0.000	0.000	0.000	0.000

Top

Graph

Overview

Highlights

Manual

Support

Interactive mode: IFIE and PIEDA for fragment #399(:389:V6D)