FMO DATABASE

FMODB ID: K9J53

Calculation Name: 6XKI-A-MD433-73ns

Preferred Name:

Target Type:

Ligand Name: (3s,6z,8e,11s,15r)-15-amino-3-[(1e,3e,5e)-7-(dimethylamino)-2,5-dimethylhepta-1,3,5-trien-1-yl]-9,11-dimethyl-4,12-dioxa-20-thia-21-azabicyclo[16.2.1]henicosa-1(21),6,8,18-tetraene-5,13-dione

ligand 3-letter code: V6D

PDB ID: 6XKI

Chain ID: A

ChEMBL ID:

UniProt ID:

Base Structure: MD

Registration Date: 2023-09-19

Reference: Hironori Saito, Yuma Handa, Mingming Chen, Tilman Schneider-Poetsch, Yuichi Shichino, Mari Takahashi, Daniel Romo, Minoru Yoshida, Alois F�rstner, Takuhiro Ito, Kaori Fukuzawa, Shintaro Iwasaki Pateamine A mediates RNA sequence-selective translation repression by anchoring eIF4A and DDX3 to GNG motifs, To be published.

DOI:

IFIE MAP

IFIE Diagram

Modeling method

Optimization	AMBER14SB
Restraint	OptAll(Heavy atoms were optimized with constraints.)
Protonation	BaseStructure_original
Complement	MOE:Structure Preparation
Water	No
Procedure	Manual calculation

FMO calculation

FMO method	FMO2-MP2/6-31G(d)
Fragmentation	Manual
Number of fragment	400
LigandCharge
Software	ABINIT-MP - Open Ver. 1 Rev. 23Q2 / 20200603(SMP)

Total energy (hartree)

FMO2-HF: Electronic energy	-7629420.545289
FMO2-HF: Nuclear repulsion	7460066.683701
FMO2-HF: Total energy	-169353.861588
FMO2-MP2: Total energy	-169831.920353

3D Structure

Snapshot

Ligand structure

V6D

Ligand Interaction

Ligand binding energy (frag 399-400 : frag 1-398)

IFIE [kcal/mol]	PIEDA [kcal/mol]				Charge transfer value [e]
IFIE SUMIFIE SUM at MP2 level.	ESElectro static interaction energy.	EXExchange-repulsion energy.	CT+mixCharge transfer and mixing terms energy.	DI(MP2)Dispersion energy.	q(I=>J)Charge transfer value from I to J fragments.
-311.083438	-258.587130	50.782991	-21.837292	-81.442007	0.136113

Interactive mode: IFIE and PIEDA for fragment #399(:389:V6D)

Summations of interaction energy for fragment #399(:389:V6D)

IFIE [kcal/mol]	PIEDA [kcal/mol]				Charge transfer value [e]
IFIE SUMIFIE SUM at MP2 level.	ESElectro static interaction energy.	EXExchange-repulsion energy.	CT+mixCharge transfer and mixing terms energy.	DI(MP2)Dispersion energy.	q(I=>J)Charge transfer value from I to J fragments.
-54.967	-19.61	36.156	-14.772	-56.737	-0.088

Interaction energy analysis for fragmet #399(:389:V6D)

Snapshot

IFIE Diagram

Base fragment(s) of PIEDA/IFIE

Single fragment	Multi fragments
	Fragment list

Charge [e] FCHARGE : 0 / q_Mulliken : -0.136 / q_NPA : -0.042

Distance from base fragment(s) [Å]

Dist

Interaction energy by IFIE and PIEDA
[kcal/mol]

| Total | > | ES | > | EX | >
| CT+mix | > | DI(MP2) | >

Fragment charge [e]

FCHARGE q_Mulliken
q_NPA q(I=>J)

Residue

Res # RES

Sort

Graph Options

X Axis Label
Y Axis Max Y Axis Min
Display ES EX CT+mix DI(MP2)

frag_NumFragment number.	Res #Residue number.	RES3-letter code of amino acid residue, ligand and solvent molecule.	FCHARGEFormal charge [e].	q_MullikenFragment charge evaluated by Mulliken charge [e].	q_NPAFragment charge evaluated by natural population analysis(NPA) charge [e].	DISTDistance from Ligand [Å].	TotalIFIE at MP2 level [kcal/mol].	ESElectro static interaction energy by PIEDA [kcal/mol].	EXExchange-repulsion energy by PIEDA [kcal/mol].	CT+mixCharge transfer and mixing terms energy by PIEDA [kcal/mol].	DI(MP2)Dispersion energy by PIEDA [kcal/mol].	q(I=>J)Charge transfer value from I to J fragmens [e].
131	131	PRO	0	0.029	0.002	3.146	-1.377	-0.163	0.598	-0.367	-1.444	0.000
132	132	GLY	0	0.032	0.016	2.412	-3.792	-1.525	8.269	-4.985	-5.551	-0.010
133	133	ARG	1	0.849	0.886	2.607	2.756	-0.880	1.160	4.789	-2.313	-0.016
134	134	VAL	0	0.028	0.013	5.067	-0.312	-0.134	-0.001	-0.011	-0.167	0.000
135	135	PHE	0	0.000	-0.009	2.606	-11.570	-4.073	7.633	-3.512	-11.617	0.003
136	136	ASP	-1	-0.791	-0.863	2.589	-6.673	-3.681	1.208	-1.523	-2.677	-0.010
137	137	MET	0	-0.010	-0.008	3.299	1.101	1.030	0.040	0.388	-0.357	0.000
139	139	ASN	0	-0.056	-0.015	2.582	-0.581	0.518	1.043	-0.586	-1.556	-0.001
140	140	ARG	1	0.831	0.909	4.657	1.514	1.649	-0.001	-0.015	-0.119	0.000
166	166	ASP	-1	-0.885	-0.934	4.342	0.062	0.150	-0.001	-0.015	-0.072	0.000
167	167	GLN	0	0.010	0.006	2.552	-9.611	-4.335	5.342	-2.884	-7.734	0.006
168	168	ILE	0	0.022	0.007	3.181	-2.673	-2.529	0.114	1.032	-1.290	-0.003
170	170	ASP	-1	-0.866	-0.939	2.492	-7.031	-2.602	2.121	-2.658	-3.891	-0.032
171	171	ILE	0	-0.041	-0.014	3.481	-0.045	0.792	0.034	-0.123	-0.748	0.000
172	172	PHE	0	0.019	0.004	5.377	0.391	0.403	-0.001	-0.002	-0.009	0.000
391	385	G	0	-0.322	-0.286	2.951	-3.060	-1.689	0.089	-0.486	-0.974	-0.003
392	385	G	-1	-0.423	-0.569	2.789	-5.041	-2.996	0.346	-0.764	-1.626	-0.003
393	386	G	0	-0.361	-0.312	2.749	-8.518	-0.418	7.216	-2.304	-13.011	-0.021
394	386	G	-1	-0.542	-0.645	2.530	-1.343	0.037	0.947	-0.746	-1.581	0.002
1	1	GLU	0	-0.099	-0.066	35.672	0.002	0.002	0.000	0.000	0.000	0.000
2	2	ILE	0	-0.031	-0.026	35.016	-0.004	-0.004	0.000	0.000	0.000	0.000
3	3	VAL	0	0.023	0.032	33.724	0.002	0.002	0.000	0.000	0.000	0.000
4	4	ASP	-1	-0.898	-0.931	36.670	-0.062	-0.062	0.000	0.000	0.000	0.000
5	5	SER	0	-0.021	-0.036	37.908	-0.004	-0.004	0.000	0.000	0.000	0.000
6	6	PHE	0	0.050	-0.011	31.153	-0.002	-0.002	0.000	0.000	0.000	0.000
7	7	ASP	-1	-0.874	-0.937	35.531	-0.090	-0.090	0.000	0.000	0.000	0.000
8	8	ASP	-1	-0.863	-0.918	38.194	-0.070	-0.070	0.000	0.000	0.000	0.000
9	9	MET	0	-0.093	-0.045	31.386	-0.003	-0.003	0.000	0.000	0.000	0.000
10	10	ASN	0	-0.072	-0.033	33.892	-0.001	-0.001	0.000	0.000	0.000	0.000
11	11	LEU	0	-0.028	-0.009	30.772	-0.004	-0.004	0.000	0.000	0.000	0.000
12	12	SER	0	0.032	0.015	32.103	0.003	0.003	0.000	0.000	0.000	0.000
13	13	GLU	-1	-0.879	-0.949	34.188	-0.093	-0.093	0.000	0.000	0.000	0.000
14	14	SER	0	-0.049	-0.034	33.727	0.003	0.003	0.000	0.000	0.000	0.000
15	15	LEU	0	0.016	0.019	28.527	-0.007	-0.007	0.000	0.000	0.000	0.000
16	16	LEU	0	-0.005	-0.002	31.895	-0.004	-0.004	0.000	0.000	0.000	0.000
17	17	ARG	1	0.941	0.976	34.704	0.113	0.113	0.000	0.000	0.000	0.000
18	18	GLY	0	0.049	0.030	31.558	0.001	0.001	0.000	0.000	0.000	0.000
19	19	ILE	0	-0.052	-0.034	30.431	-0.003	-0.003	0.000	0.000	0.000	0.000
20	20	TYR	0	-0.010	-0.016	32.419	0.001	0.001	0.000	0.000	0.000	0.000
21	21	ALA	0	-0.042	0.000	33.451	0.004	0.004	0.000	0.000	0.000	0.000
22	22	TYR	0	-0.058	-0.042	26.825	-0.003	-0.003	0.000	0.000	0.000	0.000
23	23	GLY	0	0.024	0.027	32.014	-0.001	-0.001	0.000	0.000	0.000	0.000
24	24	PHE	0	-0.083	-0.037	28.667	0.004	0.004	0.000	0.000	0.000	0.000
25	25	GLU	-1	-0.898	-0.957	34.379	-0.083	-0.083	0.000	0.000	0.000	0.000
26	26	LYS	1	0.875	0.927	36.273	0.086	0.086	0.000	0.000	0.000	0.000
27	27	PRO	0	0.009	0.033	33.019	-0.004	-0.004	0.000	0.000	0.000	0.000
28	28	SER	0	0.007	-0.024	30.427	0.009	0.009	0.000	0.000	0.000	0.000
29	29	ALA	0	0.078	0.029	33.280	0.000	0.000	0.000	0.000	0.000	0.000
30	30	ILE	0	-0.032	-0.010	27.167	0.005	0.005	0.000	0.000	0.000	0.000
31	31	GLN	0	0.022	0.008	27.831	0.008	0.008	0.000	0.000	0.000	0.000
32	32	GLN	0	-0.013	-0.008	30.169	0.000	0.000	0.000	0.000	0.000	0.000
33	33	ARG	1	0.891	0.944	31.269	0.075	0.075	0.000	0.000	0.000	0.000
34	34	ALA	0	0.007	0.005	26.210	0.002	0.002	0.000	0.000	0.000	0.000
35	35	ILE	0	0.046	0.030	26.827	-0.004	-0.004	0.000	0.000	0.000	0.000
36	36	LEU	0	0.048	0.034	27.939	-0.004	-0.004	0.000	0.000	0.000	0.000
37	37	PRO	0	-0.039	-0.036	27.255	0.000	0.000	0.000	0.000	0.000	0.000
38	38	CYS	0	-0.014	-0.001	23.917	-0.004	-0.004	0.000	0.000	0.000	0.000
39	39	ILE	0	0.053	0.032	24.990	-0.006	-0.006	0.000	0.000	0.000	0.000
40	40	LYS	1	0.897	0.963	27.356	0.077	0.077	0.000	0.000	0.000	0.000
41	41	GLY	0	0.045	0.038	23.951	0.006	0.006	0.000	0.000	0.000	0.000
42	42	TYR	0	-0.049	-0.030	23.402	0.003	0.003	0.000	0.000	0.000	0.000
43	43	ASP	-1	-0.705	-0.835	19.736	-0.135	-0.135	0.000	0.000	0.000	0.000
44	44	VAL	0	-0.023	-0.018	20.839	0.016	0.016	0.000	0.000	0.000	0.000
45	45	ILE	0	0.012	0.010	20.005	-0.016	-0.016	0.000	0.000	0.000	0.000
46	46	ALA	0	0.014	-0.013	22.109	0.011	0.011	0.000	0.000	0.000	0.000
47	47	GLN	0	-0.009	0.003	23.230	-0.006	-0.006	0.000	0.000	0.000	0.000
48	48	ALA	0	-0.019	-0.015	23.566	0.006	0.006	0.000	0.000	0.000	0.000
49	49	GLN	0	0.090	0.038	24.605	-0.014	-0.014	0.000	0.000	0.000	0.000
50	50	SER	0	0.003	0.020	25.826	-0.011	-0.011	0.000	0.000	0.000	0.000
51	51	GLY	0	0.012	0.007	26.910	0.008	0.008	0.000	0.000	0.000	0.000
52	52	THR	0	-0.044	-0.034	27.870	0.006	0.006	0.000	0.000	0.000	0.000
53	53	GLY	0	0.062	0.045	27.153	0.002	0.002	0.000	0.000	0.000	0.000
54	54	LYS	1	0.805	0.888	19.292	0.208	0.208	0.000	0.000	0.000	0.000
55	55	THR	0	0.039	0.013	20.308	0.000	0.000	0.000	0.000	0.000	0.000
56	56	ALA	0	0.034	0.010	22.208	-0.007	-0.007	0.000	0.000	0.000	0.000
57	57	THR	0	-0.003	-0.010	23.878	0.008	0.008	0.000	0.000	0.000	0.000
58	58	PHE	0	0.039	0.022	18.162	0.004	0.004	0.000	0.000	0.000	0.000
59	59	ALA	0	0.003	0.007	21.651	-0.007	-0.007	0.000	0.000	0.000	0.000
60	60	ILE	0	0.012	0.007	22.988	0.000	0.000	0.000	0.000	0.000	0.000
61	61	SER	0	-0.027	-0.035	22.906	0.009	0.009	0.000	0.000	0.000	0.000
62	62	ILE	0	-0.005	0.004	18.155	-0.001	-0.001	0.000	0.000	0.000	0.000
63	63	LEU	0	-0.015	-0.005	22.509	0.003	0.003	0.000	0.000	0.000	0.000
64	64	GLN	0	0.046	0.022	25.309	0.004	0.004	0.000	0.000	0.000	0.000
65	65	GLN	0	-0.098	-0.058	23.209	0.020	0.020	0.000	0.000	0.000	0.000
66	66	ILE	0	-0.064	-0.016	21.970	-0.010	-0.010	0.000	0.000	0.000	0.000
67	67	GLU	-1	-0.869	-0.927	25.131	-0.136	-0.136	0.000	0.000	0.000	0.000
68	68	LEU	0	0.032	-0.009	25.639	-0.018	-0.018	0.000	0.000	0.000	0.000
69	69	ASP	-1	-0.898	-0.934	27.513	-0.147	-0.147	0.000	0.000	0.000	0.000
70	70	LEU	0	-0.126	-0.048	21.819	-0.001	-0.001	0.000	0.000	0.000	0.000
71	71	LYS	1	0.960	0.975	22.508	0.210	0.210	0.000	0.000	0.000	0.000
72	72	ALA	0	0.008	-0.008	18.162	-0.009	-0.009	0.000	0.000	0.000	0.000
73	73	THR	0	-0.021	-0.009	15.072	-0.006	-0.006	0.000	0.000	0.000	0.000
74	74	GLN	0	-0.049	-0.022	16.633	-0.003	-0.003	0.000	0.000	0.000	0.000
75	75	ALA	0	0.000	0.005	17.206	0.013	0.013	0.000	0.000	0.000	0.000
76	76	LEU	0	-0.012	-0.005	9.512	-0.039	-0.039	0.000	0.000	0.000	0.000
77	77	VAL	0	-0.004	-0.004	13.253	0.041	0.041	0.000	0.000	0.000	0.000
78	78	LEU	0	-0.012	-0.008	7.117	-0.078	-0.078	0.000	0.000	0.000	0.000
79	79	ALA	0	0.034	-0.003	10.032	0.089	0.089	0.000	0.000	0.000	0.000
80	80	PRO	0	0.014	0.001	9.167	-0.105	-0.105	0.000	0.000	0.000	0.000
81	81	THR	0	0.015	0.010	8.616	-0.142	-0.142	0.000	0.000	0.000	0.000
82	82	ARG	1	0.865	0.894	7.042	1.402	1.402	0.000	0.000	0.000	0.000
83	83	GLU	-1	-0.753	-0.864	11.238	-0.478	-0.478	0.000	0.000	0.000	0.000
84	84	LEU	0	-0.035	-0.008	13.715	0.055	0.055	0.000	0.000	0.000	0.000
85	85	ALA	0	0.013	0.008	11.665	0.039	0.039	0.000	0.000	0.000	0.000
86	86	GLN	0	0.053	0.019	13.781	0.042	0.042	0.000	0.000	0.000	0.000
87	87	GLN	0	-0.053	-0.005	16.366	0.040	0.040	0.000	0.000	0.000	0.000
88	88	ILE	0	0.013	-0.005	15.109	0.028	0.028	0.000	0.000	0.000	0.000
89	89	GLN	0	0.051	0.022	17.176	0.011	0.011	0.000	0.000	0.000	0.000
90	90	LYS	1	0.892	0.941	18.874	0.346	0.346	0.000	0.000	0.000	0.000
91	91	VAL	0	-0.015	0.005	21.870	0.018	0.018	0.000	0.000	0.000	0.000
92	92	VAL	0	0.027	0.006	19.781	0.017	0.017	0.000	0.000	0.000	0.000
93	93	MET	0	-0.010	0.010	22.304	0.008	0.008	0.000	0.000	0.000	0.000
94	94	ALA	0	-0.029	-0.013	24.716	0.016	0.016	0.000	0.000	0.000	0.000
95	95	LEU	0	-0.036	-0.015	25.323	0.014	0.014	0.000	0.000	0.000	0.000
96	96	GLY	0	0.021	-0.001	26.322	0.011	0.011	0.000	0.000	0.000	0.000
97	97	ASP	-1	-0.943	-0.969	27.351	-0.178	-0.178	0.000	0.000	0.000	0.000
98	98	TYR	0	-0.015	-0.005	29.409	0.011	0.011	0.000	0.000	0.000	0.000
99	99	MET	0	-0.063	-0.037	28.489	0.005	0.005	0.000	0.000	0.000	0.000
100	100	GLY	0	0.020	0.030	30.113	0.004	0.004	0.000	0.000	0.000	0.000
101	101	ALA	0	-0.042	-0.019	24.932	-0.008	-0.008	0.000	0.000	0.000	0.000
102	102	SER	0	-0.059	-0.050	22.849	-0.007	-0.007	0.000	0.000	0.000	0.000
103	103	CYS	0	-0.047	-0.029	18.679	-0.022	-0.022	0.000	0.000	0.000	0.000
104	104	HIS	0	-0.042	-0.045	12.713	0.073	0.073	0.000	0.000	0.000	0.000
105	105	ALA	0	0.027	0.018	14.248	-0.016	-0.016	0.000	0.000	0.000	0.000
106	106	CYS	0	-0.053	-0.022	9.208	-0.003	-0.003	0.000	0.000	0.000	0.000
107	107	ILE	0	-0.004	0.004	9.268	-0.093	-0.093	0.000	0.000	0.000	0.000
108	108	GLY	0	-0.006	-0.002	7.446	0.021	0.021	0.000	0.000	0.000	0.000
109	109	GLY	0	0.018	0.002	8.130	0.091	0.091	0.000	0.000	0.000	0.000
110	110	THR	0	0.002	0.006	10.290	0.130	0.130	0.000	0.000	0.000	0.000
111	111	ASN	0	0.033	0.014	10.749	-0.076	-0.076	0.000	0.000	0.000	0.000
112	112	VAL	0	0.077	0.042	7.613	0.019	0.019	0.000	0.000	0.000	0.000
113	113	ARG	1	0.892	0.944	10.903	0.313	0.313	0.000	0.000	0.000	0.000
114	114	ALA	0	0.052	0.016	13.197	0.017	0.017	0.000	0.000	0.000	0.000
115	115	GLU	-1	-0.730	-0.835	10.646	-0.843	-0.843	0.000	0.000	0.000	0.000
116	116	VAL	0	0.008	-0.009	10.923	0.023	0.023	0.000	0.000	0.000	0.000
117	117	GLN	0	-0.012	0.001	13.050	0.038	0.038	0.000	0.000	0.000	0.000
118	118	LYS	1	0.964	0.984	16.622	0.381	0.381	0.000	0.000	0.000	0.000
119	119	LEU	0	-0.003	-0.015	12.381	0.027	0.027	0.000	0.000	0.000	0.000
120	120	GLN	0	0.004	-0.005	14.821	0.048	0.048	0.000	0.000	0.000	0.000
121	121	MET	0	-0.109	-0.035	17.780	0.043	0.043	0.000	0.000	0.000	0.000
122	122	GLU	-1	-0.901	-0.928	19.871	-0.254	-0.254	0.000	0.000	0.000	0.000
123	123	ALA	0	-0.052	-0.023	18.382	0.021	0.021	0.000	0.000	0.000	0.000
124	124	PRO	0	0.001	0.021	17.162	0.019	0.019	0.000	0.000	0.000	0.000
125	125	HIS	0	0.098	0.061	18.695	-0.045	-0.045	0.000	0.000	0.000	0.000
126	126	ILE	0	-0.051	-0.027	17.775	-0.007	-0.007	0.000	0.000	0.000	0.000
127	127	ILE	0	0.006	-0.007	12.331	-0.023	-0.023	0.000	0.000	0.000	0.000
128	128	VAL	0	0.013	0.015	13.347	0.008	0.008	0.000	0.000	0.000	0.000
129	129	GLY	0	0.003	-0.012	10.037	-0.025	-0.025	0.000	0.000	0.000	0.000
130	130	THR	0	0.004	-0.011	5.840	0.190	0.190	0.000	0.000	0.000	0.000
138	138	LEU	0	-0.030	-0.013	5.194	0.345	0.345	0.000	0.000	0.000	0.000
141	141	ARG	1	0.888	0.941	7.362	0.532	0.532	0.000	0.000	0.000	0.000
142	142	TYR	0	-0.002	-0.004	9.827	0.109	0.109	0.000	0.000	0.000	0.000
143	143	LEU	0	0.036	0.036	8.779	0.097	0.097	0.000	0.000	0.000	0.000
144	144	SER	0	0.033	-0.004	10.035	-0.016	-0.016	0.000	0.000	0.000	0.000
145	145	PRO	0	0.030	0.012	11.616	0.026	0.026	0.000	0.000	0.000	0.000
146	146	LYS	1	0.856	0.930	14.474	0.232	0.232	0.000	0.000	0.000	0.000
147	147	TYR	0	0.012	-0.006	15.859	0.029	0.029	0.000	0.000	0.000	0.000
148	148	ILE	0	0.008	0.019	12.026	0.011	0.011	0.000	0.000	0.000	0.000
149	149	LYS	1	0.919	0.964	16.474	0.214	0.214	0.000	0.000	0.000	0.000
150	150	MET	0	-0.005	0.010	17.650	0.024	0.024	0.000	0.000	0.000	0.000
151	151	PHE	0	-0.002	-0.008	8.844	-0.050	-0.050	0.000	0.000	0.000	0.000
152	152	VAL	0	0.003	-0.002	14.027	0.048	0.048	0.000	0.000	0.000	0.000
153	153	LEU	0	-0.002	0.007	10.091	-0.050	-0.050	0.000	0.000	0.000	0.000
154	154	ASP	-1	-0.776	-0.881	13.759	-0.221	-0.221	0.000	0.000	0.000	0.000
155	155	GLU	-1	-0.825	-0.907	14.152	-0.230	-0.230	0.000	0.000	0.000	0.000
156	156	ALA	0	0.016	0.007	14.562	0.015	0.015	0.000	0.000	0.000	0.000
157	157	ASP	-1	-0.770	-0.818	14.716	-0.096	-0.096	0.000	0.000	0.000	0.000
158	158	GLU	-1	-0.886	-0.932	11.817	-0.132	-0.132	0.000	0.000	0.000	0.000
159	159	MET	0	-0.062	-0.006	8.235	0.022	0.022	0.000	0.000	0.000	0.000
160	160	LEU	0	-0.030	-0.019	10.197	0.062	0.062	0.000	0.000	0.000	0.000
161	161	SER	0	-0.009	-0.013	11.829	0.033	0.033	0.000	0.000	0.000	0.000
162	162	ARG	1	0.808	0.865	10.244	-0.126	-0.126	0.000	0.000	0.000	0.000
163	163	GLY	0	0.074	0.061	8.518	0.104	0.104	0.000	0.000	0.000	0.000
164	164	PHE	0	-0.026	-0.013	5.771	0.281	0.281	0.000	0.000	0.000	0.000
165	165	LYS	1	0.883	0.940	6.600	-0.158	-0.158	0.000	0.000	0.000	0.000
169	169	TYR	0	-0.008	-0.010	6.006	-0.203	-0.203	0.000	0.000	0.000	0.000
173	173	GLN	0	-0.044	-0.014	7.380	0.255	0.255	0.000	0.000	0.000	0.000
174	174	LYS	1	0.896	0.950	5.563	-0.892	-0.892	0.000	0.000	0.000	0.000
175	175	LEU	0	-0.019	0.007	9.799	0.026	0.026	0.000	0.000	0.000	0.000
176	176	ASN	0	-0.006	-0.004	12.164	0.091	0.091	0.000	0.000	0.000	0.000
177	177	SER	0	0.027	0.019	15.940	-0.017	-0.017	0.000	0.000	0.000	0.000
178	178	ASN	0	-0.047	-0.014	17.557	0.016	0.016	0.000	0.000	0.000	0.000
179	179	THR	0	-0.036	-0.036	14.551	-0.016	-0.016	0.000	0.000	0.000	0.000
180	180	GLN	0	-0.054	-0.037	17.583	0.003	0.003	0.000	0.000	0.000	0.000
181	181	VAL	0	-0.001	0.005	14.380	-0.040	-0.040	0.000	0.000	0.000	0.000
182	182	VAL	0	-0.022	-0.018	16.556	0.030	0.030	0.000	0.000	0.000	0.000
183	183	LEU	0	-0.010	-0.005	14.266	-0.025	-0.025	0.000	0.000	0.000	0.000
184	184	LEU	0	-0.002	-0.002	17.721	0.023	0.023	0.000	0.000	0.000	0.000
185	185	SER	0	-0.037	-0.061	18.359	-0.022	-0.022	0.000	0.000	0.000	0.000
186	186	ALA	0	0.020	0.020	20.456	0.013	0.013	0.000	0.000	0.000	0.000
187	187	THR	0	-0.016	-0.009	20.353	0.009	0.009	0.000	0.000	0.000	0.000
188	188	MET	0	0.000	-0.011	19.291	-0.005	-0.005	0.000	0.000	0.000	0.000
189	189	PRO	0	0.053	0.038	19.535	0.007	0.007	0.000	0.000	0.000	0.000
190	190	SER	0	0.004	-0.008	21.440	-0.002	-0.002	0.000	0.000	0.000	0.000
191	191	ASP	-1	-0.891	-0.940	20.573	0.029	0.029	0.000	0.000	0.000	0.000
192	192	VAL	0	-0.017	-0.010	15.994	0.009	0.009	0.000	0.000	0.000	0.000
193	193	LEU	0	0.003	-0.010	18.285	-0.008	-0.008	0.000	0.000	0.000	0.000
194	194	GLU	-1	-0.874	-0.907	20.739	0.009	0.009	0.000	0.000	0.000	0.000
195	195	VAL	0	-0.005	-0.001	14.307	0.004	0.004	0.000	0.000	0.000	0.000
196	196	THR	0	-0.021	-0.027	16.040	-0.008	-0.008	0.000	0.000	0.000	0.000
197	197	LYS	1	0.861	0.912	16.870	-0.022	-0.022	0.000	0.000	0.000	0.000
198	198	LYS	1	0.884	0.964	10.101	-0.028	-0.028	0.000	0.000	0.000	0.000
199	199	PHE	0	-0.026	-0.022	9.431	-0.002	-0.002	0.000	0.000	0.000	0.000
200	200	MET	0	-0.071	-0.019	14.635	-0.014	-0.014	0.000	0.000	0.000	0.000
201	201	ARG	1	0.829	0.905	18.282	0.129	0.129	0.000	0.000	0.000	0.000
202	202	ASP	-1	-0.944	-0.979	21.426	-0.021	-0.021	0.000	0.000	0.000	0.000
203	203	PRO	0	-0.029	0.003	21.314	-0.004	-0.004	0.000	0.000	0.000	0.000
204	204	ILE	0	0.014	0.009	23.494	0.010	0.010	0.000	0.000	0.000	0.000
205	205	ARG	1	0.930	0.962	23.384	0.033	0.033	0.000	0.000	0.000	0.000
206	206	ILE	0	-0.011	0.000	26.072	0.006	0.006	0.000	0.000	0.000	0.000
207	207	LEU	0	-0.002	-0.005	25.079	-0.006	-0.006	0.000	0.000	0.000	0.000
208	208	VAL	0	-0.002	-0.008	28.064	0.001	0.001	0.000	0.000	0.000	0.000
209	209	LYS	1	0.964	0.992	29.350	0.033	0.033	0.000	0.000	0.000	0.000
210	210	LYS	1	0.934	0.960	27.912	0.023	0.023	0.000	0.000	0.000	0.000
211	211	GLU	-1	-0.888	-0.949	30.304	-0.038	-0.038	0.000	0.000	0.000	0.000
212	212	GLU	-1	-0.957	-0.960	32.628	-0.061	-0.061	0.000	0.000	0.000	0.000
213	213	LEU	0	-0.063	-0.033	26.281	-0.004	-0.004	0.000	0.000	0.000	0.000
214	214	THR	0	-0.020	-0.015	29.759	-0.006	-0.006	0.000	0.000	0.000	0.000
215	215	LEU	0	0.003	0.007	28.026	-0.003	-0.003	0.000	0.000	0.000	0.000
216	216	GLU	-1	-0.807	-0.892	32.579	-0.060	-0.060	0.000	0.000	0.000	0.000
217	217	GLY	0	-0.110	-0.052	35.128	0.003	0.003	0.000	0.000	0.000	0.000
218	218	ILE	0	-0.035	-0.026	30.206	-0.001	-0.001	0.000	0.000	0.000	0.000
219	219	ARG	1	0.884	0.948	34.253	0.073	0.073	0.000	0.000	0.000	0.000
220	220	GLN	0	0.062	0.039	32.659	-0.005	-0.005	0.000	0.000	0.000	0.000
221	221	PHE	0	0.043	0.011	35.014	0.004	0.004	0.000	0.000	0.000	0.000
222	222	TYR	0	-0.030	-0.022	34.760	-0.003	-0.003	0.000	0.000	0.000	0.000
223	223	ILE	0	0.061	0.023	35.474	0.002	0.002	0.000	0.000	0.000	0.000
224	224	ASN	0	-0.031	-0.022	36.464	-0.001	-0.001	0.000	0.000	0.000	0.000
225	225	VAL	0	0.036	0.020	35.785	0.000	0.000	0.000	0.000	0.000	0.000
226	226	GLU	-1	-0.841	-0.885	38.540	-0.014	-0.014	0.000	0.000	0.000	0.000
227	227	ARG	1	0.915	0.935	36.689	0.026	0.026	0.000	0.000	0.000	0.000
228	228	GLU	-1	-0.714	-0.849	29.978	-0.046	-0.046	0.000	0.000	0.000	0.000
229	229	GLU	-1	-0.974	-0.987	34.574	-0.024	-0.024	0.000	0.000	0.000	0.000
230	230	TRP	0	-0.006	0.007	37.229	0.000	0.000	0.000	0.000	0.000	0.000
231	231	LYS	1	0.812	0.904	29.017	0.050	0.050	0.000	0.000	0.000	0.000
232	232	LEU	0	0.002	-0.003	33.263	-0.004	-0.004	0.000	0.000	0.000	0.000
233	233	ASP	-1	-0.816	-0.920	34.931	-0.043	-0.043	0.000	0.000	0.000	0.000
234	234	THR	0	-0.003	0.002	36.712	0.001	0.001	0.000	0.000	0.000	0.000
235	235	LEU	0	-0.034	-0.024	31.485	-0.002	-0.002	0.000	0.000	0.000	0.000
236	236	CYS	0	-0.039	-0.014	35.715	-0.003	-0.003	0.000	0.000	0.000	0.000
237	237	ASP	-1	-0.867	-0.916	38.396	-0.045	-0.045	0.000	0.000	0.000	0.000
238	238	LEU	0	-0.041	-0.027	34.398	-0.001	-0.001	0.000	0.000	0.000	0.000
239	239	TYR	0	0.031	0.012	34.092	-0.006	-0.006	0.000	0.000	0.000	0.000
240	240	GLU	-1	-0.895	-0.931	37.613	-0.061	-0.061	0.000	0.000	0.000	0.000
241	241	THR	0	-0.080	-0.047	36.997	-0.002	-0.002	0.000	0.000	0.000	0.000
242	242	LEU	0	-0.014	-0.019	32.239	-0.004	-0.004	0.000	0.000	0.000	0.000
243	243	THR	0	-0.048	-0.023	35.675	-0.004	-0.004	0.000	0.000	0.000	0.000
244	244	ILE	0	-0.051	-0.024	38.398	-0.002	-0.002	0.000	0.000	0.000	0.000
245	245	THR	0	-0.012	-0.004	34.112	-0.003	-0.003	0.000	0.000	0.000	0.000
246	246	GLN	0	-0.077	-0.037	28.219	0.003	0.003	0.000	0.000	0.000	0.000
247	247	ALA	0	-0.014	-0.014	30.151	0.003	0.003	0.000	0.000	0.000	0.000
248	248	VAL	0	-0.027	-0.010	23.797	-0.009	-0.009	0.000	0.000	0.000	0.000
249	249	ILE	0	0.007	0.010	26.245	0.010	0.010	0.000	0.000	0.000	0.000
250	250	PHE	0	0.033	0.014	20.140	-0.012	-0.012	0.000	0.000	0.000	0.000
251	251	ILE	0	-0.028	-0.020	22.112	0.018	0.018	0.000	0.000	0.000	0.000
252	252	ASN	0	0.030	0.008	20.572	-0.026	-0.026	0.000	0.000	0.000	0.000
253	253	THR	0	-0.019	0.006	19.077	0.001	0.001	0.000	0.000	0.000	0.000
254	254	ARG	1	0.936	0.943	13.088	0.242	0.242	0.000	0.000	0.000	0.000
255	255	ARG	1	0.959	0.975	19.309	0.038	0.038	0.000	0.000	0.000	0.000
256	256	LYS	1	0.824	0.898	22.154	0.063	0.063	0.000	0.000	0.000	0.000
257	257	VAL	0	0.019	0.011	20.955	0.004	0.004	0.000	0.000	0.000	0.000
258	258	ASP	-1	-0.926	-0.954	22.125	-0.119	-0.119	0.000	0.000	0.000	0.000
259	259	TRP	0	0.010	0.016	24.079	0.008	0.008	0.000	0.000	0.000	0.000
260	260	LEU	0	-0.020	-0.020	27.069	0.005	0.005	0.000	0.000	0.000	0.000
261	261	THR	0	-0.022	-0.029	25.683	-0.002	-0.002	0.000	0.000	0.000	0.000
262	262	GLU	-1	-0.906	-0.943	28.189	-0.090	-0.090	0.000	0.000	0.000	0.000
263	263	LYS	1	0.850	0.923	30.545	0.058	0.058	0.000	0.000	0.000	0.000
264	264	MET	0	0.005	-0.008	31.604	0.006	0.006	0.000	0.000	0.000	0.000
265	265	HIS	0	0.019	0.030	32.158	-0.001	-0.001	0.000	0.000	0.000	0.000
266	266	ALA	0	-0.052	-0.031	34.016	0.004	0.004	0.000	0.000	0.000	0.000
267	267	ARG	1	0.755	0.860	36.198	0.054	0.054	0.000	0.000	0.000	0.000
268	268	ASP	-1	-0.918	-0.944	37.444	-0.059	-0.059	0.000	0.000	0.000	0.000
269	269	PHE	0	-0.018	-0.007	35.191	-0.001	-0.001	0.000	0.000	0.000	0.000
270	270	THR	0	-0.058	-0.034	32.889	-0.004	-0.004	0.000	0.000	0.000	0.000
271	271	VAL	0	0.011	0.008	29.025	-0.002	-0.002	0.000	0.000	0.000	0.000
272	272	SER	0	-0.013	-0.004	25.842	-0.004	-0.004	0.000	0.000	0.000	0.000
273	273	ALA	0	0.039	0.019	23.282	0.004	0.004	0.000	0.000	0.000	0.000
274	274	MET	0	-0.050	-0.025	17.527	-0.031	-0.031	0.000	0.000	0.000	0.000
275	275	HIS	0	0.056	0.023	16.711	-0.012	-0.012	0.000	0.000	0.000	0.000
276	276	GLY	0	0.025	-0.022	12.554	-0.024	-0.024	0.000	0.000	0.000	0.000
277	277	ASP	-1	-1.016	-1.014	12.948	-0.352	-0.352	0.000	0.000	0.000	0.000
278	278	MET	0	-0.033	0.013	14.617	0.028	0.028	0.000	0.000	0.000	0.000
279	279	ASP	-1	-0.876	-0.946	15.439	-0.361	-0.361	0.000	0.000	0.000	0.000
280	280	GLN	0	0.016	0.008	12.549	-0.072	-0.072	0.000	0.000	0.000	0.000
281	281	LYS	1	0.919	0.952	15.270	0.251	0.251	0.000	0.000	0.000	0.000
282	282	GLU	-1	-0.886	-0.940	18.355	-0.218	-0.218	0.000	0.000	0.000	0.000
283	283	ARG	1	0.762	0.844	11.262	0.685	0.685	0.000	0.000	0.000	0.000
284	284	ASP	-1	-0.936	-0.971	17.359	-0.363	-0.363	0.000	0.000	0.000	0.000
285	285	VAL	0	-0.027	-0.009	18.657	0.024	0.024	0.000	0.000	0.000	0.000
286	286	ILE	0	0.008	0.006	20.622	0.019	0.019	0.000	0.000	0.000	0.000
287	287	MET	0	0.007	0.005	18.638	0.021	0.021	0.000	0.000	0.000	0.000
288	288	ARG	1	0.826	0.914	21.805	0.215	0.215	0.000	0.000	0.000	0.000
289	289	GLU	-1	-0.830	-0.918	24.538	-0.158	-0.158	0.000	0.000	0.000	0.000
290	290	PHE	0	0.021	0.022	24.467	0.011	0.011	0.000	0.000	0.000	0.000
291	291	ARG	1	0.840	0.911	20.244	0.272	0.272	0.000	0.000	0.000	0.000
292	292	SER	0	-0.049	-0.019	26.693	0.008	0.008	0.000	0.000	0.000	0.000
293	293	GLY	0	0.022	0.020	29.326	0.009	0.009	0.000	0.000	0.000	0.000
294	294	SER	0	-0.071	-0.029	30.338	0.009	0.009	0.000	0.000	0.000	0.000
295	295	SER	0	0.000	0.006	27.001	0.011	0.011	0.000	0.000	0.000	0.000
296	296	ARG	1	0.946	0.954	29.673	0.099	0.099	0.000	0.000	0.000	0.000
297	297	VAL	0	0.066	0.034	29.940	0.001	0.001	0.000	0.000	0.000	0.000
298	298	LEU	0	-0.011	0.010	22.049	-0.002	-0.002	0.000	0.000	0.000	0.000
299	299	ILE	0	0.014	0.001	24.071	0.003	0.003	0.000	0.000	0.000	0.000
300	300	THR	0	-0.024	-0.038	19.413	-0.029	-0.029	0.000	0.000	0.000	0.000
301	301	THR	0	0.038	0.010	16.214	0.021	0.021	0.000	0.000	0.000	0.000
302	302	ASP	-1	-0.803	-0.900	16.244	-0.149	-0.149	0.000	0.000	0.000	0.000
303	303	LEU	0	-0.022	0.010	13.103	-0.018	-0.018	0.000	0.000	0.000	0.000
304	304	LEU	0	0.000	-0.011	15.079	-0.026	-0.026	0.000	0.000	0.000	0.000
305	305	ALA	0	0.001	0.004	17.594	0.023	0.023	0.000	0.000	0.000	0.000
306	306	ARG	1	0.847	0.892	15.738	0.178	0.178	0.000	0.000	0.000	0.000
307	307	GLY	0	0.023	0.021	17.586	-0.029	-0.029	0.000	0.000	0.000	0.000
308	308	ILE	0	-0.033	-0.017	16.396	0.006	0.006	0.000	0.000	0.000	0.000
309	309	ASP	-1	-0.871	-0.929	20.043	-0.156	-0.156	0.000	0.000	0.000	0.000
310	310	VAL	0	0.024	0.000	23.632	-0.011	-0.011	0.000	0.000	0.000	0.000
311	311	GLN	0	0.046	0.020	26.435	0.016	0.016	0.000	0.000	0.000	0.000
312	312	GLN	0	0.001	-0.010	30.073	0.011	0.011	0.000	0.000	0.000	0.000
313	313	VAL	0	-0.019	0.014	26.775	0.006	0.006	0.000	0.000	0.000	0.000
314	314	SER	0	-0.014	-0.013	30.190	0.001	0.001	0.000	0.000	0.000	0.000
315	315	LEU	0	-0.010	-0.010	31.839	0.003	0.003	0.000	0.000	0.000	0.000
316	316	VAL	0	-0.005	-0.001	26.894	-0.009	-0.009	0.000	0.000	0.000	0.000
317	317	ILE	0	0.027	0.012	28.642	0.009	0.009	0.000	0.000	0.000	0.000
318	318	ASN	0	-0.018	-0.011	25.894	-0.017	-0.017	0.000	0.000	0.000	0.000
319	319	TYR	0	0.056	0.021	27.311	0.008	0.008	0.000	0.000	0.000	0.000
320	320	ASP	-1	-0.786	-0.878	24.790	-0.060	-0.060	0.000	0.000	0.000	0.000
321	321	LEU	0	0.071	0.033	25.832	-0.010	-0.010	0.000	0.000	0.000	0.000
322	322	PRO	0	-0.011	0.025	22.803	0.005	0.005	0.000	0.000	0.000	0.000
323	323	THR	0	0.016	-0.009	21.409	0.011	0.011	0.000	0.000	0.000	0.000
324	324	ASN	0	0.014	0.006	19.368	-0.004	-0.004	0.000	0.000	0.000	0.000
325	325	ARG	1	0.991	0.993	21.730	0.009	0.009	0.000	0.000	0.000	0.000
326	326	GLU	-1	-0.855	-0.923	20.815	-0.041	-0.041	0.000	0.000	0.000	0.000
327	327	ASN	0	-0.073	-0.052	18.418	-0.003	-0.003	0.000	0.000	0.000	0.000
328	328	TYR	0	0.013	0.003	21.038	-0.013	-0.013	0.000	0.000	0.000	0.000
329	329	ILE	0	0.012	0.005	24.427	-0.006	-0.006	0.000	0.000	0.000	0.000
330	330	HIS	0	-0.061	-0.033	20.652	-0.018	-0.018	0.000	0.000	0.000	0.000
331	331	ARG	1	0.848	0.905	20.646	0.105	0.105	0.000	0.000	0.000	0.000
332	332	ILE	0	0.032	0.010	23.544	-0.004	-0.004	0.000	0.000	0.000	0.000
333	333	GLY	0	0.020	0.020	25.891	0.001	0.001	0.000	0.000	0.000	0.000
334	334	ARG	1	0.743	0.859	21.616	0.175	0.175	0.000	0.000	0.000	0.000
335	335	GLY	0	0.017	0.015	25.669	-0.002	-0.002	0.000	0.000	0.000	0.000
336	336	GLY	0	-0.007	-0.001	29.526	0.000	0.000	0.000	0.000	0.000	0.000
337	337	ARG	1	0.776	0.901	25.053	0.160	0.160	0.000	0.000	0.000	0.000
338	338	PHE	0	-0.019	-0.028	29.921	0.006	0.006	0.000	0.000	0.000	0.000
339	339	GLY	0	-0.001	0.003	31.929	0.005	0.005	0.000	0.000	0.000	0.000
340	340	ARG	1	0.875	0.951	33.827	0.117	0.117	0.000	0.000	0.000	0.000
341	341	LYS	1	0.925	0.957	34.481	0.068	0.068	0.000	0.000	0.000	0.000
342	342	GLY	0	0.094	0.043	33.458	-0.004	-0.004	0.000	0.000	0.000	0.000
343	343	VAL	0	-0.042	-0.005	33.744	0.007	0.007	0.000	0.000	0.000	0.000
344	344	ALA	0	0.007	0.002	30.545	-0.008	-0.008	0.000	0.000	0.000	0.000
345	345	ILE	0	0.019	0.014	31.815	0.007	0.007	0.000	0.000	0.000	0.000
346	346	ASN	0	-0.009	-0.009	30.213	-0.009	-0.009	0.000	0.000	0.000	0.000
347	347	MET	0	-0.006	0.007	31.407	0.003	0.003	0.000	0.000	0.000	0.000
348	348	VAL	0	-0.043	-0.013	31.736	0.001	0.001	0.000	0.000	0.000	0.000
349	349	THR	0	-0.019	-0.033	32.904	0.002	0.002	0.000	0.000	0.000	0.000
350	350	GLU	-1	-0.945	-0.984	35.294	-0.003	-0.003	0.000	0.000	0.000	0.000
351	351	GLU	-1	-0.939	-0.974	32.130	0.006	0.006	0.000	0.000	0.000	0.000
352	352	ASP	-1	-0.860	-0.894	30.261	-0.029	-0.029	0.000	0.000	0.000	0.000
353	353	LYS	1	0.823	0.898	32.347	0.014	0.014	0.000	0.000	0.000	0.000
354	354	ARG	1	0.865	0.917	33.925	0.004	0.004	0.000	0.000	0.000	0.000
355	355	THR	0	0.061	0.026	27.805	0.001	0.001	0.000	0.000	0.000	0.000
356	356	LEU	0	0.028	0.017	30.627	-0.004	-0.004	0.000	0.000	0.000	0.000
357	357	ARG	1	0.860	0.929	32.555	0.018	0.018	0.000	0.000	0.000	0.000
358	358	ASP	-1	-0.856	-0.914	30.229	-0.004	-0.004	0.000	0.000	0.000	0.000
359	359	ILE	0	-0.028	-0.010	27.768	-0.001	-0.001	0.000	0.000	0.000	0.000
360	360	GLU	-1	-0.797	-0.878	30.287	-0.032	-0.032	0.000	0.000	0.000	0.000
361	361	THR	0	-0.068	-0.066	33.769	0.001	0.001	0.000	0.000	0.000	0.000
362	362	PHE	0	-0.037	-0.009	25.496	0.003	0.003	0.000	0.000	0.000	0.000
363	363	TYR	0	-0.062	-0.070	25.672	-0.004	-0.004	0.000	0.000	0.000	0.000
364	364	ASN	0	-0.107	-0.050	32.251	0.001	0.001	0.000	0.000	0.000	0.000
365	365	THR	0	-0.007	0.000	33.636	-0.002	-0.002	0.000	0.000	0.000	0.000
366	366	SER	0	-0.075	-0.068	36.653	0.005	0.005	0.000	0.000	0.000	0.000
367	367	ILE	0	-0.060	-0.023	32.585	-0.004	-0.004	0.000	0.000	0.000	0.000
368	368	GLU	-1	-0.840	-0.888	36.972	-0.035	-0.035	0.000	0.000	0.000	0.000
369	369	GLU	-1	-0.954	-0.984	39.186	-0.031	-0.031	0.000	0.000	0.000	0.000
370	370	MET	0	-0.053	-0.016	38.968	-0.003	-0.003	0.000	0.000	0.000	0.000
371	371	PRO	0	-0.008	0.003	41.005	0.003	0.003	0.000	0.000	0.000	0.000
372	372	LEU	0	0.014	0.004	43.761	-0.001	-0.001	0.000	0.000	0.000	0.000
373	373	ASN	0	-0.060	-0.038	46.064	0.001	0.001	0.000	0.000	0.000	0.000
374	374	VAL	0	0.054	0.026	39.406	-0.001	-0.001	0.000	0.000	0.000	0.000
375	375	ALA	0	0.034	0.001	41.400	-0.003	-0.003	0.000	0.000	0.000	0.000
376	376	ASP	-1	-0.919	-0.947	42.373	-0.054	-0.054	0.000	0.000	0.000	0.000
377	377	LEU	0	-0.141	-0.070	40.223	0.000	0.000	0.000	0.000	0.000	0.000
378	378	ILE	-1	-0.886	-0.907	36.683	-0.085	-0.085	0.000	0.000	0.000	0.000
379	379	A	0	-0.364	-0.302	19.458	-0.009	-0.009	0.000	0.000	0.000	0.000
380	379	A	-1	-0.530	-0.626	13.821	0.267	0.267	0.000	0.000	0.000	0.000
381	380	G	0	-0.357	-0.303	17.887	-0.019	-0.019	0.000	0.000	0.000	0.000
382	380	G	-1	-0.546	-0.639	14.724	0.268	0.268	0.000	0.000	0.000	0.000
383	381	A	0	-0.372	-0.307	17.198	-0.018	-0.018	0.000	0.000	0.000	0.000
384	381	A	-1	-0.622	-0.683	15.040	0.045	0.045	0.000	0.000	0.000	0.000
385	382	G	0	-0.326	-0.280	13.148	0.075	0.075	0.000	0.000	0.000	0.000
386	382	G	-1	-0.510	-0.673	15.689	-0.112	-0.112	0.000	0.000	0.000	0.000
387	383	A	0	-0.334	-0.296	9.865	-0.026	-0.026	0.000	0.000	0.000	0.000
388	383	A	-1	-0.492	-0.595	11.348	-0.324	-0.324	0.000	0.000	0.000	0.000
389	384	G	0	-0.394	-0.334	5.605	-0.228	-0.228	0.000	0.000	0.000	0.000
390	384	G	-1	-0.474	-0.567	6.867	-0.671	-0.671	0.000	0.000	0.000	0.000
395	387	G	0	-0.330	-0.291	5.695	0.124	0.124	0.000	0.000	0.000	0.000
396	387	G	-1	-0.711	-0.735	7.130	-0.443	-0.443	0.000	0.000	0.000	0.000
397	388	G	0	-0.366	-0.301	9.270	0.099	0.099	0.000	0.000	0.000	0.000
398	388	G	0	0.304	0.248	8.950	0.036	0.036	0.000	0.000	0.000	0.000

Top

Graph

Overview

Highlights

Manual

Support

Interactive mode: IFIE and PIEDA for fragment #399(:389:V6D)