FMO DATABASE

FMODB ID: Z6K8N

Calculation Name: 6XKI-A-MD433-82ns

Preferred Name:

Target Type:

Ligand Name: (3s,6z,8e,11s,15r)-15-amino-3-[(1e,3e,5e)-7-(dimethylamino)-2,5-dimethylhepta-1,3,5-trien-1-yl]-9,11-dimethyl-4,12-dioxa-20-thia-21-azabicyclo[16.2.1]henicosa-1(21),6,8,18-tetraene-5,13-dione

ligand 3-letter code: V6D

PDB ID: 6XKI

Chain ID: A

ChEMBL ID:

UniProt ID:

Base Structure: MD

Registration Date: 2023-09-19

Reference: Hironori Saito, Yuma Handa, Mingming Chen, Tilman Schneider-Poetsch, Yuichi Shichino, Mari Takahashi, Daniel Romo, Minoru Yoshida, Alois F�rstner, Takuhiro Ito, Kaori Fukuzawa, Shintaro Iwasaki Pateamine A mediates RNA sequence-selective translation repression by anchoring eIF4A and DDX3 to GNG motifs, To be published.

DOI:

IFIE MAP

IFIE Diagram

Modeling method

Optimization	AMBER14SB
Restraint	OptAll(Heavy atoms were optimized with constraints.)
Protonation	BaseStructure_original
Complement	MOE:Structure Preparation
Water	No
Procedure	Manual calculation

FMO calculation

FMO method	FMO2-MP2/6-31G(d)
Fragmentation	Manual
Number of fragment	400
LigandCharge	V6D=1
Software	ABINIT-MP - Open Ver. 1 Rev. 23Q2 / 20200603(SMP)

Total energy (hartree)

FMO2-HF: Electronic energy	-7601233.893166
FMO2-HF: Nuclear repulsion	7431880.057251
FMO2-HF: Total energy	-169353.835915
FMO2-MP2: Total energy	-169831.9185

3D Structure

Snapshot

Ligand structure

V6D

Ligand Interaction

Ligand binding energy (frag 399-400 : frag 1-398)

IFIE [kcal/mol]	PIEDA [kcal/mol]				Charge transfer value [e]
IFIE SUMIFIE SUM at MP2 level.	ESElectro static interaction energy.	EXExchange-repulsion energy.	CT+mixCharge transfer and mixing terms energy.	DI(MP2)Dispersion energy.	q(I=>J)Charge transfer value from I to J fragments.
-287.342009	-238.928885	46.455466	-21.028921	-73.839669	0.106834

Interactive mode: IFIE and PIEDA for fragment #399(:389:V6D)

Summations of interaction energy for fragment #399(:389:V6D)

IFIE [kcal/mol]	PIEDA [kcal/mol]				Charge transfer value [e]
IFIE SUMIFIE SUM at MP2 level.	ESElectro static interaction energy.	EXExchange-repulsion energy.	CT+mixCharge transfer and mixing terms energy.	DI(MP2)Dispersion energy.	q(I=>J)Charge transfer value from I to J fragments.
-235.786	-219.72	11.037	-6.181	-20.923	-0.026

Interaction energy analysis for fragmet #399(:389:V6D)

Snapshot

IFIE Diagram

Base fragment(s) of PIEDA/IFIE

Single fragment	Multi fragments
	Fragment list

Charge [e] FCHARGE : 1 / q_Mulliken : 1.016 / q_NPA : 1.017

Distance from base fragment(s) [Å]

Dist

Interaction energy by IFIE and PIEDA
[kcal/mol]

| Total | > | ES | > | EX | >
| CT+mix | > | DI(MP2) | >

Fragment charge [e]

FCHARGE q_Mulliken
q_NPA q(I=>J)

Residue

Res # RES

Sort

Graph Options

X Axis Label
Y Axis Max Y Axis Min
Display ES EX CT+mix DI(MP2)

frag_NumFragment number.	Res #Residue number.	RES3-letter code of amino acid residue, ligand and solvent molecule.	FCHARGEFormal charge [e].	q_MullikenFragment charge evaluated by Mulliken charge [e].	q_NPAFragment charge evaluated by natural population analysis(NPA) charge [e].	DISTDistance from Ligand [Å].	TotalIFIE at MP2 level [kcal/mol].	ESElectro static interaction energy by PIEDA [kcal/mol].	EXExchange-repulsion energy by PIEDA [kcal/mol].	CT+mixCharge transfer and mixing terms energy by PIEDA [kcal/mol].	DI(MP2)Dispersion energy by PIEDA [kcal/mol].	q(I=>J)Charge transfer value from I to J fragmens [e].
82	82	ARG	1	0.848	0.886	2.459	45.743	45.685	1.969	-0.360	-1.551	0.000
132	132	GLY	0	0.032	0.022	2.947	0.511	0.388	0.063	-0.061	0.121	0.000
133	133	ARG	1	0.821	0.857	3.759	27.873	27.987	0.002	0.013	-0.130	0.000
167	167	GLN	0	0.040	0.024	4.676	-1.388	-1.238	-0.001	-0.018	-0.132	0.000
254	254	ARG	1	0.952	0.943	3.137	47.500	47.912	0.009	-0.067	-0.353	0.000
276	276	GLY	0	0.014	-0.020	4.862	-0.801	-0.783	-0.001	-0.025	0.008	0.000
277	277	ASP	-1	-1.044	-1.011	2.500	-61.412	-58.837	0.932	-1.511	-1.996	-0.022
278	278	MET	0	-0.005	0.017	3.798	-2.320	-1.940	0.008	-0.143	-0.245	-0.001
279	279	ASP	-1	-0.798	-0.884	4.183	-37.155	-36.970	0.000	-0.029	-0.156	0.000
390	384	G	-1	-0.454	-0.556	4.095	-39.468	-39.042	0.001	-0.059	-0.367	0.000
391	385	G	0	-0.305	-0.279	2.737	-14.089	-6.899	3.584	-2.249	-8.526	-0.013
392	385	G	-1	-0.475	-0.586	2.211	-40.870	-37.098	3.392	-2.633	-4.532	0.004
393	386	G	0	-0.375	-0.322	2.901	-4.314	-3.014	0.932	-0.348	-1.883	0.007
394	386	G	-1	-0.558	-0.638	3.044	-36.306	-36.786	0.147	1.318	-0.985	-0.001
397	388	G	0	-0.360	-0.297	4.232	6.133	6.338	0.000	-0.009	-0.196	0.000
1	1	GLU	0	-0.073	-0.054	43.960	0.188	0.188	0.000	0.000	0.000	0.000
2	2	ILE	0	-0.018	-0.006	39.749	-0.105	-0.105	0.000	0.000	0.000	0.000
3	3	VAL	0	0.043	0.039	37.952	0.098	0.098	0.000	0.000	0.000	0.000
4	4	ASP	-1	-0.885	-0.945	40.519	-6.823	-6.823	0.000	0.000	0.000	0.000
5	5	SER	0	0.014	-0.012	40.441	-0.109	-0.109	0.000	0.000	0.000	0.000
6	6	PHE	0	0.006	-0.017	33.434	-0.049	-0.049	0.000	0.000	0.000	0.000
7	7	ASP	-1	-0.879	-0.940	37.773	-7.205	-7.205	0.000	0.000	0.000	0.000
8	8	ASP	-1	-0.853	-0.917	40.081	-6.734	-6.734	0.000	0.000	0.000	0.000
9	9	MET	0	-0.188	-0.092	35.260	-0.085	-0.085	0.000	0.000	0.000	0.000
10	10	ASN	0	-0.060	-0.034	36.971	-0.068	-0.068	0.000	0.000	0.000	0.000
11	11	LEU	0	-0.004	0.006	33.581	-0.146	-0.146	0.000	0.000	0.000	0.000
12	12	SER	0	0.020	0.007	35.165	0.181	0.181	0.000	0.000	0.000	0.000
13	13	GLU	-1	-0.797	-0.899	36.928	-7.250	-7.250	0.000	0.000	0.000	0.000
14	14	SER	0	-0.031	-0.019	35.500	-0.013	-0.013	0.000	0.000	0.000	0.000
15	15	LEU	0	0.031	0.010	30.356	-0.169	-0.169	0.000	0.000	0.000	0.000
16	16	LEU	0	-0.008	0.000	33.905	-0.175	-0.175	0.000	0.000	0.000	0.000
17	17	ARG	1	0.863	0.927	36.551	7.231	7.231	0.000	0.000	0.000	0.000
18	18	GLY	0	0.050	0.038	32.876	-0.029	-0.029	0.000	0.000	0.000	0.000
19	19	ILE	0	-0.046	-0.035	32.267	-0.188	-0.188	0.000	0.000	0.000	0.000
20	20	TYR	0	0.001	-0.011	33.820	-0.013	-0.013	0.000	0.000	0.000	0.000
21	21	ALA	0	-0.016	0.002	34.314	0.044	0.044	0.000	0.000	0.000	0.000
22	22	TYR	0	-0.086	-0.047	26.207	-0.274	-0.274	0.000	0.000	0.000	0.000
23	23	GLY	0	0.013	0.014	32.245	-0.147	-0.147	0.000	0.000	0.000	0.000
24	24	PHE	0	-0.091	-0.039	29.328	0.018	0.018	0.000	0.000	0.000	0.000
25	25	GLU	-1	-0.862	-0.929	35.371	-7.497	-7.497	0.000	0.000	0.000	0.000
26	26	LYS	1	0.910	0.946	37.841	7.506	7.506	0.000	0.000	0.000	0.000
27	27	PRO	0	-0.033	0.010	35.420	-0.226	-0.226	0.000	0.000	0.000	0.000
28	28	SER	0	0.001	-0.027	31.833	0.196	0.196	0.000	0.000	0.000	0.000
29	29	ALA	0	0.027	0.001	35.057	0.029	0.029	0.000	0.000	0.000	0.000
30	30	ILE	0	0.031	0.015	28.720	0.121	0.121	0.000	0.000	0.000	0.000
31	31	GLN	0	0.050	0.039	30.005	0.236	0.236	0.000	0.000	0.000	0.000
32	32	GLN	0	-0.014	-0.008	32.641	0.004	0.004	0.000	0.000	0.000	0.000
33	33	ARG	1	0.826	0.901	33.598	8.106	8.106	0.000	0.000	0.000	0.000
34	34	ALA	0	0.027	0.006	28.672	0.022	0.022	0.000	0.000	0.000	0.000
35	35	ILE	0	0.033	0.035	29.652	-0.164	-0.164	0.000	0.000	0.000	0.000
36	36	LEU	0	0.019	0.006	31.004	-0.026	-0.026	0.000	0.000	0.000	0.000
37	37	PRO	0	-0.040	-0.019	30.572	0.040	0.040	0.000	0.000	0.000	0.000
38	38	CYS	0	0.022	0.024	25.898	-0.120	-0.120	0.000	0.000	0.000	0.000
39	39	ILE	0	0.056	0.024	28.820	-0.055	-0.055	0.000	0.000	0.000	0.000
40	40	LYS	1	0.883	0.937	31.206	7.775	7.775	0.000	0.000	0.000	0.000
41	41	GLY	0	0.023	0.030	29.119	0.139	0.139	0.000	0.000	0.000	0.000
42	42	TYR	0	-0.020	-0.006	29.162	0.032	0.032	0.000	0.000	0.000	0.000
43	43	ASP	-1	-0.732	-0.835	24.976	-10.719	-10.719	0.000	0.000	0.000	0.000
44	44	VAL	0	-0.046	-0.031	25.199	0.304	0.304	0.000	0.000	0.000	0.000
45	45	ILE	0	-0.006	-0.008	23.818	-0.428	-0.428	0.000	0.000	0.000	0.000
46	46	ALA	0	0.006	-0.016	24.710	0.436	0.436	0.000	0.000	0.000	0.000
47	47	GLN	0	0.022	0.004	25.120	-0.196	-0.196	0.000	0.000	0.000	0.000
48	48	ALA	0	-0.044	-0.036	26.247	0.430	0.430	0.000	0.000	0.000	0.000
49	49	GLN	0	0.109	0.063	26.618	-0.702	-0.702	0.000	0.000	0.000	0.000
50	50	SER	0	0.009	-0.004	26.501	-0.169	-0.169	0.000	0.000	0.000	0.000
51	51	GLY	0	0.002	0.002	26.944	0.316	0.316	0.000	0.000	0.000	0.000
52	52	THR	0	-0.039	-0.017	28.773	0.172	0.172	0.000	0.000	0.000	0.000
53	53	GLY	0	0.071	0.047	27.921	0.248	0.248	0.000	0.000	0.000	0.000
54	54	LYS	1	0.807	0.898	20.536	13.363	13.363	0.000	0.000	0.000	0.000
55	55	THR	0	0.045	0.010	20.980	-0.080	-0.080	0.000	0.000	0.000	0.000
56	56	ALA	0	0.060	0.026	23.431	0.004	0.004	0.000	0.000	0.000	0.000
57	57	THR	0	-0.019	-0.010	26.435	0.338	0.338	0.000	0.000	0.000	0.000
58	58	PHE	0	0.043	0.027	19.516	0.264	0.264	0.000	0.000	0.000	0.000
59	59	ALA	0	0.003	0.013	23.811	0.085	0.085	0.000	0.000	0.000	0.000
60	60	ILE	0	0.035	0.015	24.793	0.159	0.159	0.000	0.000	0.000	0.000
61	61	SER	0	-0.028	-0.039	26.453	0.331	0.331	0.000	0.000	0.000	0.000
62	62	ILE	0	-0.016	-0.001	21.369	0.109	0.109	0.000	0.000	0.000	0.000
63	63	LEU	0	-0.004	-0.013	25.729	0.221	0.221	0.000	0.000	0.000	0.000
64	64	GLN	0	0.040	0.027	27.896	0.167	0.167	0.000	0.000	0.000	0.000
65	65	GLN	0	-0.112	-0.061	27.960	0.334	0.334	0.000	0.000	0.000	0.000
66	66	ILE	0	-0.089	-0.025	24.342	-0.018	-0.018	0.000	0.000	0.000	0.000
67	67	GLU	-1	-0.866	-0.918	28.459	-8.092	-8.092	0.000	0.000	0.000	0.000
68	68	LEU	0	0.008	-0.012	29.382	-0.312	-0.312	0.000	0.000	0.000	0.000
69	69	ASP	-1	-0.945	-0.964	30.797	-8.373	-8.373	0.000	0.000	0.000	0.000
70	70	LEU	0	-0.026	-0.009	27.027	-0.056	-0.056	0.000	0.000	0.000	0.000
71	71	LYS	1	0.965	0.981	26.845	9.340	9.340	0.000	0.000	0.000	0.000
72	72	ALA	0	0.010	-0.006	23.396	-0.115	-0.115	0.000	0.000	0.000	0.000
73	73	THR	0	-0.043	-0.015	17.665	-0.105	-0.105	0.000	0.000	0.000	0.000
74	74	GLN	0	0.000	-0.002	21.036	-0.015	-0.015	0.000	0.000	0.000	0.000
75	75	ALA	0	-0.041	-0.019	20.509	0.171	0.171	0.000	0.000	0.000	0.000
76	76	LEU	0	-0.009	-0.004	13.155	-0.274	-0.274	0.000	0.000	0.000	0.000
77	77	VAL	0	-0.004	0.002	16.030	0.110	0.110	0.000	0.000	0.000	0.000
78	78	LEU	0	0.002	-0.004	10.120	-0.875	-0.875	0.000	0.000	0.000	0.000
79	79	ALA	0	0.028	-0.006	11.359	1.071	1.071	0.000	0.000	0.000	0.000
80	80	PRO	0	0.022	0.014	10.071	-1.378	-1.378	0.000	0.000	0.000	0.000
81	81	THR	0	0.010	-0.010	7.625	-1.880	-1.880	0.000	0.000	0.000	0.000
83	83	GLU	-1	-0.729	-0.852	9.123	-25.140	-25.140	0.000	0.000	0.000	0.000
84	84	LEU	0	-0.027	-0.001	11.837	1.618	1.618	0.000	0.000	0.000	0.000
85	85	ALA	0	-0.002	-0.003	12.008	1.280	1.280	0.000	0.000	0.000	0.000
86	86	GLN	0	0.026	0.001	12.966	0.766	0.766	0.000	0.000	0.000	0.000
87	87	GLN	0	-0.001	0.015	15.526	0.703	0.703	0.000	0.000	0.000	0.000
88	88	ILE	0	-0.008	-0.003	15.723	0.875	0.875	0.000	0.000	0.000	0.000
89	89	GLN	0	0.034	0.011	17.554	0.427	0.427	0.000	0.000	0.000	0.000
90	90	LYS	1	0.954	0.979	19.476	12.080	12.080	0.000	0.000	0.000	0.000
91	91	VAL	0	-0.043	-0.019	22.110	0.535	0.535	0.000	0.000	0.000	0.000
92	92	VAL	0	0.022	0.000	20.808	0.469	0.469	0.000	0.000	0.000	0.000
93	93	MET	0	0.007	0.013	22.907	0.382	0.382	0.000	0.000	0.000	0.000
94	94	ALA	0	-0.030	-0.007	25.426	0.369	0.369	0.000	0.000	0.000	0.000
95	95	LEU	0	-0.032	-0.003	26.634	0.368	0.368	0.000	0.000	0.000	0.000
96	96	GLY	0	0.026	-0.001	27.886	0.332	0.332	0.000	0.000	0.000	0.000
97	97	ASP	-1	-0.938	-0.958	29.109	-9.302	-9.302	0.000	0.000	0.000	0.000
98	98	TYR	0	-0.029	-0.024	31.202	0.146	0.146	0.000	0.000	0.000	0.000
99	99	MET	0	-0.061	-0.028	30.902	0.122	0.122	0.000	0.000	0.000	0.000
100	100	GLY	0	0.018	0.024	31.093	0.109	0.109	0.000	0.000	0.000	0.000
101	101	ALA	0	-0.057	-0.021	26.798	-0.155	-0.155	0.000	0.000	0.000	0.000
102	102	SER	0	-0.051	-0.053	23.865	-0.320	-0.320	0.000	0.000	0.000	0.000
103	103	CYS	0	-0.040	-0.037	19.281	-0.168	-0.168	0.000	0.000	0.000	0.000
104	104	HIS	0	-0.029	-0.025	14.638	0.806	0.806	0.000	0.000	0.000	0.000
105	105	ALA	0	0.034	0.015	13.899	-0.195	-0.195	0.000	0.000	0.000	0.000
106	106	CYS	0	-0.070	-0.013	11.955	-0.372	-0.372	0.000	0.000	0.000	0.000
107	107	ILE	0	-0.020	-0.014	8.796	-0.804	-0.804	0.000	0.000	0.000	0.000
108	108	GLY	0	-0.007	-0.001	5.238	0.567	0.567	0.000	0.000	0.000	0.000
109	109	GLY	0	0.009	0.004	5.372	-0.326	-0.326	0.000	0.000	0.000	0.000
110	110	THR	0	0.028	0.019	6.114	1.718	1.718	0.000	0.000	0.000	0.000
111	111	ASN	0	0.041	0.011	9.743	-0.439	-0.439	0.000	0.000	0.000	0.000
112	112	VAL	0	0.078	0.047	10.391	1.244	1.244	0.000	0.000	0.000	0.000
113	113	ARG	1	0.915	0.949	12.414	18.717	18.717	0.000	0.000	0.000	0.000
114	114	ALA	0	0.025	0.011	15.758	0.919	0.919	0.000	0.000	0.000	0.000
115	115	GLU	-1	-0.760	-0.854	12.139	-19.638	-19.638	0.000	0.000	0.000	0.000
116	116	VAL	0	0.012	-0.003	15.494	0.707	0.707	0.000	0.000	0.000	0.000
117	117	GLN	0	-0.023	-0.020	16.976	0.653	0.653	0.000	0.000	0.000	0.000
118	118	LYS	1	0.962	0.998	18.430	13.537	13.537	0.000	0.000	0.000	0.000
119	119	LEU	0	0.017	-0.003	15.233	0.525	0.525	0.000	0.000	0.000	0.000
120	120	GLN	0	-0.016	-0.008	19.758	0.769	0.769	0.000	0.000	0.000	0.000
121	121	MET	0	-0.098	-0.036	22.589	0.485	0.485	0.000	0.000	0.000	0.000
122	122	GLU	-1	-0.901	-0.921	22.117	-11.152	-11.152	0.000	0.000	0.000	0.000
123	123	ALA	0	-0.045	-0.017	22.796	0.380	0.380	0.000	0.000	0.000	0.000
124	124	PRO	0	-0.003	0.009	19.646	0.304	0.304	0.000	0.000	0.000	0.000
125	125	HIS	0	0.065	0.040	21.860	-0.537	-0.537	0.000	0.000	0.000	0.000
126	126	ILE	0	-0.049	-0.022	19.543	-0.008	-0.008	0.000	0.000	0.000	0.000
127	127	ILE	0	0.000	-0.006	14.093	-0.323	-0.323	0.000	0.000	0.000	0.000
128	128	VAL	0	0.020	0.014	14.693	0.166	0.166	0.000	0.000	0.000	0.000
129	129	GLY	0	-0.008	-0.009	11.122	-0.284	-0.284	0.000	0.000	0.000	0.000
130	130	THR	0	0.004	-0.015	6.181	1.111	1.111	0.000	0.000	0.000	0.000
131	131	PRO	0	0.031	0.002	6.046	0.520	0.520	0.000	0.000	0.000	0.000
134	134	VAL	0	0.054	0.025	6.935	2.076	2.076	0.000	0.000	0.000	0.000
135	135	PHE	0	0.015	0.003	5.917	1.869	1.869	0.000	0.000	0.000	0.000
136	136	ASP	-1	-0.737	-0.841	6.940	-22.702	-22.702	0.000	0.000	0.000	0.000
137	137	MET	0	-0.036	-0.018	8.562	1.889	1.889	0.000	0.000	0.000	0.000
138	138	LEU	0	-0.014	-0.005	11.048	1.372	1.372	0.000	0.000	0.000	0.000
139	139	ASN	0	-0.068	-0.018	10.554	1.585	1.585	0.000	0.000	0.000	0.000
140	140	ARG	1	0.788	0.874	10.085	21.961	21.961	0.000	0.000	0.000	0.000
141	141	ARG	1	0.891	0.952	14.693	13.445	13.445	0.000	0.000	0.000	0.000
142	142	TYR	0	0.021	0.012	16.419	0.544	0.544	0.000	0.000	0.000	0.000
143	143	LEU	0	0.025	0.026	12.974	0.591	0.591	0.000	0.000	0.000	0.000
144	144	SER	0	0.017	-0.006	16.953	0.148	0.148	0.000	0.000	0.000	0.000
145	145	PRO	0	0.025	0.004	18.372	0.225	0.225	0.000	0.000	0.000	0.000
146	146	LYS	1	0.878	0.948	21.009	10.188	10.188	0.000	0.000	0.000	0.000
147	147	TYR	0	0.013	-0.004	22.528	0.484	0.484	0.000	0.000	0.000	0.000
148	148	ILE	0	0.001	0.016	17.084	0.108	0.108	0.000	0.000	0.000	0.000
149	149	LYS	1	0.965	0.983	21.413	9.585	9.585	0.000	0.000	0.000	0.000
150	150	MET	0	-0.037	-0.011	21.847	0.043	0.043	0.000	0.000	0.000	0.000
151	151	PHE	0	0.016	-0.001	12.942	-0.398	-0.398	0.000	0.000	0.000	0.000
152	152	VAL	0	0.027	0.005	17.163	0.471	0.471	0.000	0.000	0.000	0.000
153	153	LEU	0	0.014	0.009	13.992	-0.775	-0.775	0.000	0.000	0.000	0.000
154	154	ASP	-1	-0.802	-0.901	16.003	-13.411	-13.411	0.000	0.000	0.000	0.000
155	155	GLU	-1	-0.868	-0.942	15.573	-15.353	-15.353	0.000	0.000	0.000	0.000
156	156	ALA	0	0.015	-0.003	16.144	-0.516	-0.516	0.000	0.000	0.000	0.000
157	157	ASP	-1	-0.780	-0.832	16.405	-14.544	-14.544	0.000	0.000	0.000	0.000
158	158	GLU	-1	-0.876	-0.930	12.604	-19.551	-19.551	0.000	0.000	0.000	0.000
159	159	MET	0	-0.071	-0.012	10.848	-1.111	-1.111	0.000	0.000	0.000	0.000
160	160	LEU	0	-0.030	-0.020	12.779	-0.171	-0.171	0.000	0.000	0.000	0.000
161	161	SER	0	0.015	0.003	13.554	0.320	0.320	0.000	0.000	0.000	0.000
162	162	ARG	1	0.825	0.875	12.605	17.243	17.243	0.000	0.000	0.000	0.000
163	163	GLY	0	0.050	0.053	9.351	-0.362	-0.362	0.000	0.000	0.000	0.000
164	164	PHE	0	-0.035	-0.006	6.937	-2.158	-2.158	0.000	0.000	0.000	0.000
165	165	LYS	1	0.888	0.931	9.471	16.063	16.063	0.000	0.000	0.000	0.000
166	166	ASP	-1	-0.854	-0.911	9.616	-16.812	-16.812	0.000	0.000	0.000	0.000
168	168	ILE	0	-0.003	-0.003	7.350	0.484	0.484	0.000	0.000	0.000	0.000
169	169	TYR	0	0.004	-0.003	10.266	1.118	1.118	0.000	0.000	0.000	0.000
170	170	ASP	-1	-0.880	-0.943	8.788	-18.161	-18.161	0.000	0.000	0.000	0.000
171	171	ILE	0	-0.068	-0.038	7.130	0.772	0.772	0.000	0.000	0.000	0.000
172	172	PHE	0	-0.018	-0.011	10.915	0.896	0.896	0.000	0.000	0.000	0.000
173	173	GLN	0	0.000	-0.005	14.038	0.866	0.866	0.000	0.000	0.000	0.000
174	174	LYS	1	0.873	0.948	12.405	15.815	15.815	0.000	0.000	0.000	0.000
175	175	LEU	0	-0.012	0.012	15.269	0.483	0.483	0.000	0.000	0.000	0.000
176	176	ASN	0	0.026	0.021	17.702	0.447	0.447	0.000	0.000	0.000	0.000
177	177	SER	0	0.037	0.031	21.423	-0.063	-0.063	0.000	0.000	0.000	0.000
178	178	ASN	0	-0.063	-0.048	23.035	0.188	0.188	0.000	0.000	0.000	0.000
179	179	THR	0	-0.052	-0.023	19.566	0.141	0.141	0.000	0.000	0.000	0.000
180	180	GLN	0	-0.024	-0.006	22.743	-0.116	-0.116	0.000	0.000	0.000	0.000
181	181	VAL	0	-0.014	-0.016	19.554	-0.471	-0.471	0.000	0.000	0.000	0.000
182	182	VAL	0	0.007	-0.004	20.840	0.490	0.490	0.000	0.000	0.000	0.000
183	183	LEU	0	0.006	0.006	18.234	-0.616	-0.616	0.000	0.000	0.000	0.000
184	184	LEU	0	0.006	-0.002	20.076	0.617	0.617	0.000	0.000	0.000	0.000
185	185	SER	0	-0.046	-0.050	20.033	-0.670	-0.670	0.000	0.000	0.000	0.000
186	186	ALA	0	0.058	0.038	21.930	0.526	0.526	0.000	0.000	0.000	0.000
187	187	THR	0	-0.034	-0.027	21.146	0.472	0.472	0.000	0.000	0.000	0.000
188	188	MET	0	-0.029	-0.025	22.081	-0.257	-0.257	0.000	0.000	0.000	0.000
189	189	PRO	0	0.060	0.048	22.457	0.515	0.515	0.000	0.000	0.000	0.000
190	190	SER	0	0.001	-0.011	24.550	-0.117	-0.117	0.000	0.000	0.000	0.000
191	191	ASP	-1	-0.880	-0.931	22.585	-11.482	-11.482	0.000	0.000	0.000	0.000
192	192	VAL	0	-0.036	-0.016	18.913	-0.264	-0.264	0.000	0.000	0.000	0.000
193	193	LEU	0	-0.002	-0.016	21.196	-0.009	-0.009	0.000	0.000	0.000	0.000
194	194	GLU	-1	-0.876	-0.886	23.620	-10.105	-10.105	0.000	0.000	0.000	0.000
195	195	VAL	0	0.005	-0.008	18.010	0.184	0.184	0.000	0.000	0.000	0.000
196	196	THR	0	-0.035	-0.035	20.119	-0.058	-0.058	0.000	0.000	0.000	0.000
197	197	LYS	1	0.855	0.919	21.587	10.168	10.168	0.000	0.000	0.000	0.000
198	198	LYS	1	0.845	0.946	15.425	14.436	14.436	0.000	0.000	0.000	0.000
199	199	PHE	0	-0.026	-0.018	14.771	-0.215	-0.215	0.000	0.000	0.000	0.000
200	200	MET	0	-0.047	-0.017	20.157	0.052	0.052	0.000	0.000	0.000	0.000
201	201	ARG	1	0.792	0.859	22.876	10.723	10.723	0.000	0.000	0.000	0.000
202	202	ASP	-1	-0.971	-0.980	27.188	-8.221	-8.221	0.000	0.000	0.000	0.000
203	203	PRO	0	-0.001	0.010	26.414	0.080	0.080	0.000	0.000	0.000	0.000
204	204	ILE	0	0.031	0.029	28.858	0.255	0.255	0.000	0.000	0.000	0.000
205	205	ARG	1	0.929	0.951	27.728	9.234	9.234	0.000	0.000	0.000	0.000
206	206	ILE	0	-0.022	-0.004	29.019	0.338	0.338	0.000	0.000	0.000	0.000
207	207	LEU	0	-0.023	-0.014	27.677	-0.319	-0.319	0.000	0.000	0.000	0.000
208	208	VAL	0	-0.004	0.004	29.157	0.309	0.309	0.000	0.000	0.000	0.000
209	209	LYS	1	0.954	0.976	30.359	7.877	7.877	0.000	0.000	0.000	0.000
210	210	LYS	1	0.980	0.984	29.022	9.513	9.513	0.000	0.000	0.000	0.000
211	211	GLU	-1	-0.877	-0.949	30.919	-8.834	-8.834	0.000	0.000	0.000	0.000
212	212	GLU	-1	-1.018	-0.996	32.682	-8.518	-8.518	0.000	0.000	0.000	0.000
213	213	LEU	0	-0.033	-0.013	26.610	-0.099	-0.099	0.000	0.000	0.000	0.000
214	214	THR	0	0.021	0.010	28.965	-0.331	-0.331	0.000	0.000	0.000	0.000
215	215	LEU	0	-0.017	-0.003	26.913	0.160	0.160	0.000	0.000	0.000	0.000
216	216	GLU	-1	-0.921	-0.962	31.025	-8.803	-8.803	0.000	0.000	0.000	0.000
217	217	GLY	0	-0.025	-0.006	33.277	0.191	0.191	0.000	0.000	0.000	0.000
218	218	ILE	0	-0.059	-0.030	29.084	-0.023	-0.023	0.000	0.000	0.000	0.000
219	219	ARG	1	0.838	0.916	32.361	8.802	8.802	0.000	0.000	0.000	0.000
220	220	GLN	0	0.053	0.033	30.251	-0.497	-0.497	0.000	0.000	0.000	0.000
221	221	PHE	0	0.044	0.009	31.819	0.299	0.299	0.000	0.000	0.000	0.000
222	222	TYR	0	-0.008	-0.007	31.337	-0.439	-0.439	0.000	0.000	0.000	0.000
223	223	ILE	0	0.056	0.022	30.332	0.257	0.257	0.000	0.000	0.000	0.000
224	224	ASN	0	-0.034	-0.031	32.291	-0.439	-0.439	0.000	0.000	0.000	0.000
225	225	VAL	0	0.013	0.005	29.454	0.181	0.181	0.000	0.000	0.000	0.000
226	226	GLU	-1	-0.887	-0.913	32.908	-8.343	-8.343	0.000	0.000	0.000	0.000
227	227	ARG	1	0.912	0.942	31.181	8.872	8.872	0.000	0.000	0.000	0.000
228	228	GLU	-1	-0.724	-0.858	23.450	-12.678	-12.678	0.000	0.000	0.000	0.000
229	229	GLU	-1	-0.977	-1.002	27.174	-10.803	-10.803	0.000	0.000	0.000	0.000
230	230	TRP	0	-0.010	0.010	29.104	0.100	0.100	0.000	0.000	0.000	0.000
231	231	LYS	1	0.797	0.894	22.991	12.747	12.747	0.000	0.000	0.000	0.000
232	232	LEU	0	0.020	0.006	23.861	-0.109	-0.109	0.000	0.000	0.000	0.000
233	233	ASP	-1	-0.815	-0.909	26.283	-10.048	-10.048	0.000	0.000	0.000	0.000
234	234	THR	0	0.004	0.001	29.390	0.260	0.260	0.000	0.000	0.000	0.000
235	235	LEU	0	-0.020	-0.018	23.069	0.054	0.054	0.000	0.000	0.000	0.000
236	236	CYS	0	-0.111	-0.062	27.499	-0.068	-0.068	0.000	0.000	0.000	0.000
237	237	ASP	-1	-0.898	-0.934	29.176	-8.797	-8.797	0.000	0.000	0.000	0.000
238	238	LEU	0	-0.033	-0.006	27.840	0.176	0.176	0.000	0.000	0.000	0.000
239	239	TYR	0	0.042	0.011	25.294	-0.176	-0.176	0.000	0.000	0.000	0.000
240	240	GLU	-1	-0.920	-0.947	29.880	-8.510	-8.510	0.000	0.000	0.000	0.000
241	241	THR	0	-0.037	-0.035	30.202	-0.031	-0.031	0.000	0.000	0.000	0.000
242	242	LEU	0	-0.033	-0.015	25.174	-0.142	-0.142	0.000	0.000	0.000	0.000
243	243	THR	0	-0.060	-0.030	27.988	-0.181	-0.181	0.000	0.000	0.000	0.000
244	244	ILE	0	-0.023	-0.015	30.624	-0.002	-0.002	0.000	0.000	0.000	0.000
245	245	THR	0	-0.032	-0.018	29.123	0.008	0.008	0.000	0.000	0.000	0.000
246	246	GLN	0	-0.029	0.000	21.962	0.288	0.288	0.000	0.000	0.000	0.000
247	247	ALA	0	0.003	-0.010	24.153	0.179	0.179	0.000	0.000	0.000	0.000
248	248	VAL	0	-0.023	-0.014	18.103	-0.489	-0.489	0.000	0.000	0.000	0.000
249	249	ILE	0	0.003	0.003	19.600	0.520	0.520	0.000	0.000	0.000	0.000
250	250	PHE	0	0.026	0.010	16.265	-0.911	-0.911	0.000	0.000	0.000	0.000
251	251	ILE	0	-0.043	-0.023	15.437	0.878	0.878	0.000	0.000	0.000	0.000
252	252	ASN	0	0.020	-0.006	15.736	-0.961	-0.961	0.000	0.000	0.000	0.000
253	253	THR	0	-0.023	-0.007	12.976	-0.618	-0.618	0.000	0.000	0.000	0.000
255	255	ARG	1	0.939	0.970	10.880	21.408	21.408	0.000	0.000	0.000	0.000
256	256	LYS	1	0.826	0.894	12.976	15.200	15.200	0.000	0.000	0.000	0.000
257	257	VAL	0	0.053	0.036	12.495	1.027	1.027	0.000	0.000	0.000	0.000
258	258	ASP	-1	-0.807	-0.877	10.906	-23.535	-23.535	0.000	0.000	0.000	0.000
259	259	TRP	0	-0.027	-0.014	14.240	1.072	1.072	0.000	0.000	0.000	0.000
260	260	LEU	0	-0.006	-0.007	17.581	0.855	0.855	0.000	0.000	0.000	0.000
261	261	THR	0	-0.004	-0.021	16.054	0.734	0.734	0.000	0.000	0.000	0.000
262	262	GLU	-1	-0.957	-0.968	17.986	-14.688	-14.688	0.000	0.000	0.000	0.000
263	263	LYS	1	0.894	0.945	19.610	14.369	14.369	0.000	0.000	0.000	0.000
264	264	MET	0	-0.010	-0.010	21.819	0.665	0.665	0.000	0.000	0.000	0.000
265	265	HIS	0	-0.007	0.000	21.045	0.328	0.328	0.000	0.000	0.000	0.000
266	266	ALA	0	-0.006	-0.001	23.058	0.402	0.402	0.000	0.000	0.000	0.000
267	267	ARG	1	0.785	0.882	25.342	10.975	10.975	0.000	0.000	0.000	0.000
268	268	ASP	-1	-0.916	-0.938	26.715	-10.021	-10.021	0.000	0.000	0.000	0.000
269	269	PHE	0	-0.017	-0.009	25.385	0.288	0.288	0.000	0.000	0.000	0.000
270	270	THR	0	-0.058	-0.032	24.353	-0.389	-0.389	0.000	0.000	0.000	0.000
271	271	VAL	0	-0.025	-0.004	20.206	-0.133	-0.133	0.000	0.000	0.000	0.000
272	272	SER	0	0.000	0.001	16.845	-0.398	-0.398	0.000	0.000	0.000	0.000
273	273	ALA	0	0.019	0.005	13.345	0.287	0.287	0.000	0.000	0.000	0.000
274	274	MET	0	-0.006	-0.002	10.052	-1.177	-1.177	0.000	0.000	0.000	0.000
275	275	HIS	0	0.011	-0.019	7.832	-1.997	-1.997	0.000	0.000	0.000	0.000
280	280	GLN	0	0.017	0.012	5.650	-1.337	-1.337	0.000	0.000	0.000	0.000
281	281	LYS	1	0.801	0.870	6.949	29.469	29.469	0.000	0.000	0.000	0.000
282	282	GLU	-1	-0.883	-0.938	9.093	-19.273	-19.273	0.000	0.000	0.000	0.000
283	283	ARG	1	0.761	0.835	4.819	39.929	39.929	0.000	0.000	0.000	0.000
284	284	ASP	-1	-0.947	-0.963	9.909	-17.093	-17.093	0.000	0.000	0.000	0.000
285	285	VAL	0	0.040	0.026	12.788	1.510	1.510	0.000	0.000	0.000	0.000
286	286	ILE	0	0.024	0.009	12.424	1.338	1.338	0.000	0.000	0.000	0.000
287	287	MET	0	-0.007	0.007	13.765	1.774	1.774	0.000	0.000	0.000	0.000
288	288	ARG	1	0.913	0.954	15.450	16.028	16.028	0.000	0.000	0.000	0.000
289	289	GLU	-1	-0.835	-0.906	17.780	-12.973	-12.973	0.000	0.000	0.000	0.000
290	290	PHE	0	0.007	0.011	18.035	0.801	0.801	0.000	0.000	0.000	0.000
291	291	ARG	1	0.833	0.903	17.139	16.428	16.428	0.000	0.000	0.000	0.000
292	292	SER	0	-0.054	-0.040	21.425	0.630	0.630	0.000	0.000	0.000	0.000
293	293	GLY	0	-0.026	-0.005	23.331	0.490	0.490	0.000	0.000	0.000	0.000
294	294	SER	0	-0.098	-0.043	22.233	0.550	0.550	0.000	0.000	0.000	0.000
295	295	SER	0	0.024	-0.001	18.626	0.387	0.387	0.000	0.000	0.000	0.000
296	296	ARG	1	0.901	0.958	21.625	10.227	10.227	0.000	0.000	0.000	0.000
297	297	VAL	0	0.075	0.026	21.775	0.152	0.152	0.000	0.000	0.000	0.000
298	298	LEU	0	-0.014	0.009	14.879	-0.296	-0.296	0.000	0.000	0.000	0.000
299	299	ILE	0	0.004	0.001	16.064	0.450	0.450	0.000	0.000	0.000	0.000
300	300	THR	0	-0.020	-0.033	13.372	-1.477	-1.477	0.000	0.000	0.000	0.000
301	301	THR	0	0.034	0.011	9.577	1.320	1.320	0.000	0.000	0.000	0.000
302	302	ASP	-1	-0.781	-0.874	12.792	-17.487	-17.487	0.000	0.000	0.000	0.000
303	303	LEU	0	-0.018	0.017	7.870	0.248	0.248	0.000	0.000	0.000	0.000
304	304	LEU	0	-0.003	-0.013	11.221	0.629	0.629	0.000	0.000	0.000	0.000
305	305	ALA	0	0.027	0.012	14.429	1.332	1.332	0.000	0.000	0.000	0.000
306	306	ARG	1	0.822	0.890	14.213	16.621	16.621	0.000	0.000	0.000	0.000
307	307	GLY	0	0.040	0.013	15.731	-0.579	-0.579	0.000	0.000	0.000	0.000
308	308	ILE	0	-0.038	-0.009	14.217	0.669	0.669	0.000	0.000	0.000	0.000
309	309	ASP	-1	-0.884	-0.930	18.308	-11.521	-11.521	0.000	0.000	0.000	0.000
310	310	VAL	0	0.002	-0.010	20.720	-0.197	-0.197	0.000	0.000	0.000	0.000
311	311	GLN	0	-0.042	-0.015	23.560	0.163	0.163	0.000	0.000	0.000	0.000
312	312	GLN	0	-0.037	-0.044	25.159	0.581	0.581	0.000	0.000	0.000	0.000
313	313	VAL	0	-0.002	0.020	22.844	0.136	0.136	0.000	0.000	0.000	0.000
314	314	SER	0	-0.023	-0.013	26.118	0.140	0.140	0.000	0.000	0.000	0.000
315	315	LEU	0	0.028	0.007	26.631	0.105	0.105	0.000	0.000	0.000	0.000
316	316	VAL	0	-0.006	0.000	22.277	-0.447	-0.447	0.000	0.000	0.000	0.000
317	317	ILE	0	-0.002	0.002	23.422	0.433	0.433	0.000	0.000	0.000	0.000
318	318	ASN	0	0.000	-0.001	22.314	-1.314	-1.314	0.000	0.000	0.000	0.000
319	319	TYR	0	0.066	0.018	21.017	0.557	0.557	0.000	0.000	0.000	0.000
320	320	ASP	-1	-0.772	-0.871	19.361	-14.440	-14.440	0.000	0.000	0.000	0.000
321	321	LEU	0	0.026	0.011	21.908	-0.222	-0.222	0.000	0.000	0.000	0.000
322	322	PRO	0	-0.036	0.019	19.914	-0.212	-0.212	0.000	0.000	0.000	0.000
323	323	THR	0	0.039	-0.003	21.288	0.466	0.466	0.000	0.000	0.000	0.000
324	324	ASN	0	-0.063	-0.036	17.215	0.898	0.898	0.000	0.000	0.000	0.000
325	325	ARG	1	0.985	0.995	21.276	11.542	11.542	0.000	0.000	0.000	0.000
326	326	GLU	-1	-0.823	-0.919	21.178	-12.225	-12.225	0.000	0.000	0.000	0.000
327	327	ASN	0	-0.083	-0.061	16.878	0.413	0.413	0.000	0.000	0.000	0.000
328	328	TYR	0	0.023	0.007	19.962	-0.309	-0.309	0.000	0.000	0.000	0.000
329	329	ILE	0	0.010	0.004	23.118	0.045	0.045	0.000	0.000	0.000	0.000
330	330	HIS	0	-0.082	-0.033	19.005	0.043	0.043	0.000	0.000	0.000	0.000
331	331	ARG	1	0.824	0.877	17.087	15.895	15.895	0.000	0.000	0.000	0.000
332	332	ILE	0	0.028	0.009	20.734	0.014	0.014	0.000	0.000	0.000	0.000
333	333	GLY	0	0.001	0.020	23.240	0.344	0.344	0.000	0.000	0.000	0.000
334	334	ARG	1	0.788	0.892	18.495	14.602	14.602	0.000	0.000	0.000	0.000
335	335	GLY	0	0.008	0.016	22.421	-0.011	-0.011	0.000	0.000	0.000	0.000
336	336	GLY	0	0.001	-0.018	25.956	0.093	0.093	0.000	0.000	0.000	0.000
337	337	ARG	1	0.802	0.920	24.016	12.083	12.083	0.000	0.000	0.000	0.000
338	338	PHE	0	-0.015	-0.026	27.888	0.377	0.377	0.000	0.000	0.000	0.000
339	339	GLY	0	0.011	0.013	30.216	0.300	0.300	0.000	0.000	0.000	0.000
340	340	ARG	1	0.909	0.969	31.742	9.831	9.831	0.000	0.000	0.000	0.000
341	341	LYS	1	0.995	0.990	32.763	7.848	7.848	0.000	0.000	0.000	0.000
342	342	GLY	0	0.107	0.055	30.933	-0.243	-0.243	0.000	0.000	0.000	0.000
343	343	VAL	0	-0.063	-0.008	30.054	0.345	0.345	0.000	0.000	0.000	0.000
344	344	ALA	0	0.033	0.018	27.628	-0.414	-0.414	0.000	0.000	0.000	0.000
345	345	ILE	0	0.017	0.013	27.506	0.393	0.393	0.000	0.000	0.000	0.000
346	346	ASN	0	0.005	-0.003	26.864	-0.925	-0.925	0.000	0.000	0.000	0.000
347	347	MET	0	-0.011	0.000	26.192	0.245	0.245	0.000	0.000	0.000	0.000
348	348	VAL	0	-0.014	0.000	27.713	-0.259	-0.259	0.000	0.000	0.000	0.000
349	349	THR	0	-0.037	-0.034	28.150	0.375	0.375	0.000	0.000	0.000	0.000
350	350	GLU	-1	-0.945	-0.998	30.773	-8.525	-8.525	0.000	0.000	0.000	0.000
351	351	GLU	-1	-0.908	-0.960	28.713	-9.869	-9.869	0.000	0.000	0.000	0.000
352	352	ASP	-1	-0.857	-0.896	26.796	-11.472	-11.472	0.000	0.000	0.000	0.000
353	353	LYS	1	0.917	0.963	29.307	8.537	8.537	0.000	0.000	0.000	0.000
354	354	ARG	1	0.847	0.919	31.213	9.411	9.411	0.000	0.000	0.000	0.000
355	355	THR	0	0.039	0.013	25.577	-0.088	-0.088	0.000	0.000	0.000	0.000
356	356	LEU	0	0.031	0.016	28.945	-0.099	-0.099	0.000	0.000	0.000	0.000
357	357	ARG	1	0.887	0.944	30.783	8.495	8.495	0.000	0.000	0.000	0.000
358	358	ASP	-1	-0.841	-0.908	29.772	-9.653	-9.653	0.000	0.000	0.000	0.000
359	359	ILE	0	-0.037	-0.012	25.940	-0.117	-0.117	0.000	0.000	0.000	0.000
360	360	GLU	-1	-0.808	-0.889	29.816	-8.665	-8.665	0.000	0.000	0.000	0.000
361	361	THR	0	-0.105	-0.081	33.366	0.121	0.121	0.000	0.000	0.000	0.000
362	362	PHE	0	-0.048	-0.009	26.641	0.120	0.120	0.000	0.000	0.000	0.000
363	363	TYR	0	-0.033	-0.055	24.980	0.012	0.012	0.000	0.000	0.000	0.000
364	364	ASN	0	-0.077	-0.026	31.635	0.256	0.256	0.000	0.000	0.000	0.000
365	365	THR	0	-0.008	0.006	31.946	0.169	0.169	0.000	0.000	0.000	0.000
366	366	SER	0	-0.078	-0.071	35.183	0.029	0.029	0.000	0.000	0.000	0.000
367	367	ILE	0	-0.062	-0.023	30.869	-0.161	-0.161	0.000	0.000	0.000	0.000
368	368	GLU	-1	-0.834	-0.879	35.150	-7.898	-7.898	0.000	0.000	0.000	0.000
369	369	GLU	-1	-0.971	-0.997	35.919	-8.222	-8.222	0.000	0.000	0.000	0.000
370	370	MET	0	-0.047	-0.023	33.214	-0.020	-0.020	0.000	0.000	0.000	0.000
371	371	PRO	0	-0.047	-0.028	36.186	0.153	0.153	0.000	0.000	0.000	0.000
372	372	LEU	0	0.009	0.004	38.163	-0.104	-0.104	0.000	0.000	0.000	0.000
373	373	ASN	0	0.015	0.011	39.657	-0.114	-0.114	0.000	0.000	0.000	0.000
374	374	VAL	0	0.017	0.011	34.560	0.075	0.075	0.000	0.000	0.000	0.000
375	375	ALA	0	0.043	0.010	36.149	-0.079	-0.079	0.000	0.000	0.000	0.000
376	376	ASP	-1	-0.896	-0.930	37.187	-7.337	-7.337	0.000	0.000	0.000	0.000
377	377	LEU	0	-0.151	-0.068	36.460	0.141	0.141	0.000	0.000	0.000	0.000
378	378	ILE	-1	-0.941	-0.966	32.601	-8.705	-8.705	0.000	0.000	0.000	0.000
379	379	A	0	-0.358	-0.296	20.890	-0.045	-0.045	0.000	0.000	0.000	0.000
380	379	A	-1	-0.560	-0.641	16.635	-15.102	-15.102	0.000	0.000	0.000	0.000
381	380	G	0	-0.360	-0.314	18.181	-0.452	-0.452	0.000	0.000	0.000	0.000
382	380	G	-1	-0.495	-0.605	15.233	-17.324	-17.324	0.000	0.000	0.000	0.000
383	381	A	0	-0.349	-0.292	15.915	-0.306	-0.306	0.000	0.000	0.000	0.000
384	381	A	-1	-0.610	-0.677	13.818	-19.362	-19.362	0.000	0.000	0.000	0.000
385	382	G	0	-0.358	-0.313	12.721	-0.692	-0.692	0.000	0.000	0.000	0.000
386	382	G	-1	-0.527	-0.651	10.203	-25.247	-25.247	0.000	0.000	0.000	0.000
387	383	A	0	-0.321	-0.293	9.397	-0.422	-0.422	0.000	0.000	0.000	0.000
388	383	A	-1	-0.471	-0.585	6.162	-34.007	-34.007	0.000	0.000	0.000	0.000
389	384	G	0	-0.395	-0.333	6.205	-3.308	-3.308	0.000	0.000	0.000	0.000
395	387	G	0	-0.338	-0.286	5.410	-5.134	-5.134	0.000	0.000	0.000	0.000
396	387	G	-1	-0.694	-0.732	8.123	-21.984	-21.984	0.000	0.000	0.000	0.000
398	388	G	0	0.282	0.224	5.282	-4.047	-4.047	0.000	0.000	0.000	0.000

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Interactive mode: IFIE and PIEDA for fragment #399(:389:V6D)